Transcription Factors, TFII
"Transcription Factors, TFII" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The so-called general transcription factors that bind to RNA POLYMERASE II and that are required to initiate transcription. They include TFIIA; TFIIB; TFIID; TFIIE; TFIIF; TFIIH; TFII-I; and TFIIJ. In vivo they apparently bind in an ordered multi-step process and/or may form a large preinitiation complex called RNA polymerase II holoenzyme.
| Descriptor ID |
D019473
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| MeSH Number(s) |
D12.776.260.775.875 D12.776.930.930.875
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Transcription Factors, TFII".
Below are MeSH descriptors whose meaning is more specific than "Transcription Factors, TFII".
This graph shows the total number of publications written about "Transcription Factors, TFII" by people in this website by year, and whether "Transcription Factors, TFII" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Transcription Factors, TFII" by people in Profiles.
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Iwata-Otsubo A, Skraban CM, Yoshimura A, Sakata T, Alves CAP, Fiordaliso SK, Kuroda Y, Vengoechea J, Grochowsky A, Ernste P, Lulis L, Nesbitt A, Tayoun AA, Gray C, Towne MC, Radtke K, Normand EA, Rhodes L, Seiler C, Shirahige K, Izumi K. Biallelic variants in GTF3C5, a regulator of RNA polymerase III-mediated transcription, cause a multisystem developmental disorder. Hum Genet. 2024 Mar; 143(3):437-453.
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Petrini I, Meltzer PS, Kim IK, Lucchi M, Park KS, Fontanini G, Gao J, Zucali PA, Calabrese F, Favaretto A, Rea F, Rodriguez-Canales J, Walker RL, Pineda M, Zhu YJ, Lau C, Killian KJ, Bilke S, Voeller D, Dakshanamurthy S, Wang Y, Giaccone G. A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. Nat Genet. 2014 Aug; 46(8):844-9.
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Hoo RL, Chu JY, Yuan Y, Yeung CM, Chan KY, Chow BK. Functional identification of an intronic promoter of the human glucose-dependent insulinotropic polypeptide gene. Gene. 2010 Sep 01; 463(1-2):29-40.
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De Falco G, Giordano A. CDK9: from basal transcription to cancer and AIDS. Cancer Biol Ther. 2002 Jul-Aug; 1(4):342-7.
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Lee BS, Bi L, Garfinkel DJ, Bailis AM. Nucleotide excision repair/TFIIH helicases RAD3 and SSL2 inhibit short-sequence recombination and Ty1 retrotransposition by similar mechanisms. Mol Cell Biol. 2000 Apr; 20(7):2436-45.
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Bregman DB, Pestell RG, Kidd VJ. Cell cycle regulation and RNA polymerase II. Front Biosci. 2000 Feb 01; 5:D244-57.