"Topotecan" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antineoplastic agent used to treat ovarian cancer. It works by inhibiting DNA TOPOISOMERASES, TYPE I.
| Descriptor ID |
D019772
|
| MeSH Number(s) |
D03.132.151.850
|
| Concept/Terms |
Topotecan- Topotecan
- 9-Dimethylaminomethyl-10-hydroxycamptothecin
- 9 Dimethylaminomethyl 10 hydroxycamptothecin
Topotecan Hydrochloride- Topotecan Hydrochloride
- Hydrochloride, Topotecan
- Nogitecan Hydrochloride
- Hydrochloride, Nogitecan
- Topotecan Monohydrochloride, (S)-Isomer
SK&F-104864-A- SK&F-104864-A
- SK&F 104864 A
- SK&F104864A
- SKF-104864-A
- SKF 104864 A
- SKF104864A
|
Below are MeSH descriptors whose meaning is more general than "Topotecan".
Below are MeSH descriptors whose meaning is more specific than "Topotecan".
This graph shows the total number of publications written about "Topotecan" by people in this website by year, and whether "Topotecan" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 2 | 2 |
| 2001 | 1 | 1 | 2 |
| 2002 | 1 | 2 | 3 |
| 2003 | 0 | 2 | 2 |
| 2004 | 2 | 1 | 3 |
| 2006 | 2 | 0 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 2 | 0 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 2 | 4 | 6 |
| 2015 | 0 | 2 | 2 |
| 2016 | 1 | 3 | 4 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 2 | 3 |
| 2020 | 1 | 0 | 1 |
| 2025 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Topotecan" by people in Profiles.
-
Shields CL, Medina R, Evans H, Valdes-Perez N, Acar AB, Bansal R, Lally SE, Shields JA. HIGH-DOSE INTRAVITREAL TOPOTECAN FOR RECURRENT RETINOBLASTOMA, SUBRETINAL SEEDS, AND VITREOUS SEEDS. Retina. 2025 01 01; 45(1):1-6.
-
Sweid A, Hammoud B, Weinberg JH, Texakalidis P, Xu V, Shivashankar K, Baldassari MP, Das S, Ramesh S, Tjoumakaris S, Shields CL, Ancona-Lezama D, Lim LS, Dalvin LA, Jabbour P. Intra-Arterial Chemotherapy for Retinoblastoma in Infants =10 kg: 74 Treated Eyes with 222 IAC Sessions. AJNR Am J Neuroradiol. 2020 07; 41(7):1286-1292.
-
Ancona-Lezama D, Dalvin LA, Lucio-Alvarez JA, Jabbour P, Shields CL. OPHTHALMIC VASCULAR EVENTS AFTER INTRA-ARTERIAL CHEMOTHERAPY FOR RETINOBLASTOMA: Real-World Comparison Between Primary and Secondary Treatments. Retina. 2019 Dec; 39(12):2264-2272.
-
Selzer EB, Welch RJ, Jabbour P, Leahey AM, Shields CL. Management of retinoblastoma in older children (>5 years) using intra-arterial chemotherapy: Comparison of outcomes to prechemotherapy and intravenous chemotherapy eras. Indian J Ophthalmol. 2019 12; 67(12):2005-2011.
-
Camp DA, Lally SE, Shields CL. Heterochromia following intravitreal chemotherapy in two cases. J AAPOS. 2019 08; 23(4):241-243.
-
Dalvin LA, Ancona-Lezama D, Lucio-Alvarez JA, Masoomian B, Jabbour P, Shields CL. Ophthalmic Vascular Events after Primary Unilateral Intra-arterial Chemotherapy for Retinoblastoma in Early and Recent Eras. Ophthalmology. 2018 11; 125(11):1803-1811.
-
Federico SM, McCarville MB, Shulkin BL, Sondel PM, Hank JA, Hutson P, Meagher M, Shafer A, Ng CY, Leung W, Janssen WE, Wu J, Mao S, Brennan RC, Santana VM, Pappo AS, Furman WL. A Pilot Trial of Humanized Anti-GD2 Monoclonal Antibody (hu14.18K322A) with Chemotherapy and Natural Killer Cells in Children with Recurrent/Refractory Neuroblastoma. Clin Cancer Res. 2017 Nov 01; 23(21):6441-6449.
-
Shields CL, Alset AE, Say EA, Caywood E, Jabbour P, Shields JA. Retinoblastoma Control With Primary Intra-arterial Chemotherapy: Outcomes Before and During the Intravitreal Chemotherapy Era. J Pediatr Ophthalmol Strabismus. 2016 Sep 01; 53(5):275-84.
-
Magan T, Khoo CT, Jabbour PM, Fuller DG, Shields CL. Intra-arterial Chemotherapy for Adult Onset Retinoblastoma in a 32-Year-Old Man. J Pediatr Ophthalmol Strabismus. 2016 Jul 30; 53:e43-6.
-
Say EA, Iyer PG, Hasanreisoglu M, Lally SE, Jabbour P, Shields JA, Shields CL. Secondary and tertiary intra-arterial chemotherapy for massive persistent or recurrent subretinal retinoblastoma seeds following previous chemotherapy exposure: long-term tumor control and globe salvage in 30 eyes. J AAPOS. 2016 08; 20(4):337-42.