"Cyclin A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A cyclin subtype that has specificity for CDC2 PROTEIN KINASE and CYCLIN-DEPENDENT KINASE 2. It plays a role in progression of the CELL CYCLE through G1/S and G2/M phase transitions.
| Descriptor ID |
D019925
|
| MeSH Number(s) |
D12.644.360.262.100 D12.776.167.218.100 D12.776.476.262.100
|
| Concept/Terms |
Cyclin A- Cyclin A
- Type A Cyclin
- Cyclin, Type A
- Type A Cyclins
- Cyclins, Type A
- Adenovirus E1A-Associated Protein p60
- Adenovirus E1A Associated Protein p60
- E1A p60
|
Below are MeSH descriptors whose meaning is more general than "Cyclin A".
Below are MeSH descriptors whose meaning is more specific than "Cyclin A".
This graph shows the total number of publications written about "Cyclin A" by people in this website by year, and whether "Cyclin A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2006 | 0 | 2 | 2 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 2 | 0 | 2 |
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Below are the most recent publications written about "Cyclin A" by people in Profiles.
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Afonso DJ, Liu D, Machado DR, Pan H, Jepson JE, Rogulja D, Koh K. TARANIS Functions with Cyclin A and Cdk1 in a Novel Arousal Center to Control Sleep in Drosophila. Curr Biol. 2015 Jun 29; 25(13):1717-26.
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Afonso DJ, Machado DR, Koh K. Control of sleep by a network of cell cycle genes. Fly (Austin). 2015; 9(4):165-72.
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Wei Z, Hurtt R, Gu T, Bodzin AS, Koch WJ, Doria C. GRK2 negatively regulates IGF-1R signaling pathway and cyclins' expression in HepG2 cells. J Cell Physiol. 2013 Sep; 228(9):1897-901.
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Lee CT, Chen J, Hayashi T, Tsai SY, Sanchez JF, Errico SL, Amable R, Su TP, Lowe RH, Huestis MA, Shen J, Becker KG, Geller HM, Freed WJ. A mechanism for the inhibition of neural progenitor cell proliferation by cocaine. PLoS Med. 2008 Jun 10; 5(6):e117.
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Giordano A, Bellacchio E, Bagella L, Paggi MG. Interaction between the Cdk2/cyclin A complex and a small molecule derived from the pRb2/p130 spacer domain: a theoretical model. Cell Cycle. 2007 Nov 01; 6(21):2591-3.
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Tong WG, Ding XZ, Talamonti MS, Bell RH, Adrian TE. Leukotriene B4 receptor antagonist LY293111 induces S-phase cell cycle arrest and apoptosis in human pancreatic cancer cells. Anticancer Drugs. 2007 Jun; 18(5):535-41.
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Ujiki MB, Ding XZ, Salabat MR, Bentrem DJ, Golkar L, Milam B, Talamonti MS, Bell RH, Iwamura T, Adrian TE. Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. Mol Cancer. 2006 Dec 29; 5:76.
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Salabat MR, Ding XZ, Flesche JB, Ujiki MB, Robin TP, Talamonti MS, Bell RH, Adrian TE. On the mechanisms of 12-O-tetradecanoylphorbol-13-acetate-induced growth arrest in pancreatic cancer cells. Pancreas. 2006 Aug; 33(2):148-55.
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Tonini T, Bagella L, D'Andrilli G, Claudio PP, Giordano A. Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A. Oncogene. 2004 Jun 17; 23(28):4930-7.
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Cesi V, Tanno B, Vitali R, Mancini C, Giuffrida ML, Calabretta B, Raschell? G. Cyclin D1-dependent regulation of B-myb activity in early stages of neuroblastoma differentiation. Cell Death Differ. 2002 Nov; 9(11):1232-9.