"Adherens Junctions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Anchoring points where the CYTOSKELETON of neighboring cells are connected to each other. They are composed of specialized areas of the plasma membrane where bundles of the ACTIN CYTOSKELETON attach to the membrane through the transmembrane linkers, CADHERINS, which in turn attach through their extracellular domains to cadherins in the neighboring cell membranes. In sheets of cells, they form into adhesion belts (zonula adherens) that go all the way around a cell.
| Descriptor ID |
D022005
|
| MeSH Number(s) |
A11.284.149.165.420.020
|
| Concept/Terms |
Adherens Junctions- Adherens Junctions
- Adherens Junction
- Junction, Adherens
- Junctions, Adherens
|
Below are MeSH descriptors whose meaning is more general than "Adherens Junctions".
Below are MeSH descriptors whose meaning is more specific than "Adherens Junctions".
This graph shows the total number of publications written about "Adherens Junctions" by people in this website by year, and whether "Adherens Junctions" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 1 | 2 |
| 2017 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Adherens Junctions" by people in Profiles.
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Simonneau C, Yang J, Kong X, Kilker R, Edelstein L, Fortina P, Londin E, Horowitz A. Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen. Sci Rep. 2019 Oct 02; 9(1):14238.
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Horowitz A. Letter by Horowitz Regarding Article, "Protein Interactions at Endothelial Junctions and Signaling Mechanisms Regulating Endothelial Permeability". Circ Res. 2017 03 03; 120(5):e27.
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Leonard M, Zhang L, Zhai N, Cader A, Chan Y, Nowak RB, Fowler VM, Menko AS. Modulation of N-cadherin junctions and their role as epicenters of differentiation-specific actin regulation in the developing lens. Dev Biol. 2011 Jan 15; 349(2):363-77.
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Tsygankova OM, Ma C, Tang W, Korch C, Feldman MD, Lv Y, Brose MS, Meinkoth JL. Downregulation of Rap1GAP in human tumor cells alters cell/matrix and cell/cell adhesion. Mol Cell Biol. 2010 Jul; 30(13):3262-74.
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Nita-Lazar M, Noonan V, Rebustini I, Walker J, Menko AS, Kukuruzinska MA. Overexpression of DPAGT1 leads to aberrant N-glycosylation of E-cadherin and cellular discohesion in oral cancer. Cancer Res. 2009 Jul 15; 69(14):5673-80.