"alpha-Defensins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DEFENSINS found in azurophilic granules of neutrophils and in the secretory granules of intestinal PANETH CELLS.
| Descriptor ID |
D023084
|
| MeSH Number(s) |
D12.644.050.200.050 D12.776.543.695.054.200.050
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "alpha-Defensins".
Below are MeSH descriptors whose meaning is more specific than "alpha-Defensins".
This graph shows the total number of publications written about "alpha-Defensins" by people in this website by year, and whether "alpha-Defensins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 0 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 0 | 1 | 1 |
| 2018 | 2 | 1 | 3 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "alpha-Defensins" by people in Profiles.
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Shohat N, Yacovelli S, Chisari E, Clarkson S, Mann D, Parvizi J. Alpha-defensin does not provide additional benefit over leukocyte esterase in the diagnosis of periprosthetic joint infection. Expert Rev Mol Diagn. 2021 08; 21(8):845-849.
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Carender CN, DeMik DE, Otero JE, Noiseux NO, Brown TS, Bedard NA. What is the Clinical Utility of Synovial Alpha Defensin Testing of Antibiotic Spacers Before Reimplantation? J Arthroplasty. 2021 06; 36(6):2150-2157.
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Deirmengian C, Madigan J, Kallur Mallikarjuna S, Conway J, Higuera C, Patel R. Validation of the Alpha Defensin Lateral Flow Test for Periprosthetic Joint Infection. J Bone Joint Surg Am. 2021 Jan 20; 103(2):115-122.
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Deirmengian C, Feeley S, Kazarian GS, Kardos K. Synovial Fluid Aspirates Diluted with Saline or Blood Reduce the Sensitivity of Traditional and Contemporary Synovial Fluid Biomarkers. Clin Orthop Relat Res. 2020 08; 478(8):1805-1813.
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Samuel LT, Sultan AA, Kheir M, Villa J, Patel P, Parvizi J, Higuera CA. Positive Alpha-defensin at Reimplantation of a Two-stage Revision Arthroplasty Is Not Associated with Infection at 1 Year. Clin Orthop Relat Res. 2019 07; 477(7):1615-1621.
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Kelly MP, Darrith B, Hannon CP, Nam D, Courtney PM, Della Valle CJ. Synovial Fluid Alpha-Defensin Is an Adjunctive Tool in the Equivocal Diagnosis of Periprosthetic Joint Infection. J Arthroplasty. 2018 11; 33(11):3537-3540.
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Tarabichi M, Shohat N, Goswami K, Parvizi J. Can next generation sequencing play a role in detecting pathogens in synovial fluid? Bone Joint J. 2018 02; 100-B(2):127-133.
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Okroj KT, Calkins TE, Kayupov E, Kheir MM, Bingham JS, Beauchamp CP, Parvizi J, Della Valle CJ. The Alpha-Defensin Test for Diagnosing Periprosthetic Joint Infection in the Setting of an Adverse Local Tissue Reaction Secondary to a Failed Metal-on-Metal Bearing or Corrosion at the Head-Neck Junction. J Arthroplasty. 2018 06; 33(6):1896-1898.
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Mitchell D, Perez J, Grau L, Summers S, Rosas S, Ong A, Schneiderbauer MM, Hernandez VH. Systematic Review of Novel Synovial Fluid Markers and Polymerase Chain Reaction in the Diagnosis of Prosthetic Joint Infection. Am J Orthop (Belle Mead NJ). 2017 Jul/Aug; 46(4):190-198.
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Shahi A, Parvizi J, Kazarian GS, Higuera C, Frangiamore S, Bingham J, Beauchamp C, Valle CD, Deirmengian C. The Alpha-defensin Test for Periprosthetic Joint Infections Is Not Affected by Prior Antibiotic Administration. Clin Orthop Relat Res. 2016 Jul; 474(7):1610-5.