"Integrin alpha2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integrin alpha subunit that primarily combines with INTEGRIN BETA1 to form the INTEGRIN ALPHA2BETA1 heterodimer. It contains a domain which has homology to collagen-binding domains found in von Willebrand factor.
| Descriptor ID |
D039421
|
| MeSH Number(s) |
D12.776.543.750.705.408.100.350
|
| Concept/Terms |
Integrin alpha2- Integrin alpha2
- alpha2, Integrin
- GPIa
- alpha2 Integrin
- Integrin, alpha2
- Platelet Glycoprotein Ia
- Glycoprotein Ia, Platelet
- Antigens, CD49b
- CD49b Antigens
- VLA-2 alpha Chain
- VLA 2 alpha Chain
- alpha Chain, VLA-2
- CD49b Antigen
- Antigen, CD49b
|
Below are MeSH descriptors whose meaning is more general than "Integrin alpha2".
Below are MeSH descriptors whose meaning is more specific than "Integrin alpha2".
This graph shows the total number of publications written about "Integrin alpha2" by people in this website by year, and whether "Integrin alpha2" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 2 | 2 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Integrin alpha2" by people in Profiles.
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Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS. Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets. Blood. 2016 Apr 07; 127(14):1743-51.
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Callan MB, Werner P, Mason NJ, Meny GM, Raducha MG, Henthorn PS. Polymorphisms in canine platelet glycoproteins identify potential platelet antigens. Comp Med. 2013 Aug; 63(4):348-54.
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Balasubramaniam S, Comstock CE, Ertel A, Jeong KW, Stallcup MR, Addya S, McCue PA, Ostrander WF, Augello MA, Knudsen KE. Aberrant BAF57 signaling facilitates prometastatic phenotypes. Clin Cancer Res. 2013 May 15; 19(10):2657-67.
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Liu Q, Limthongkul W, Sidhu G, Zhang J, Vaccaro A, Shenck R, Hickok N, Shapiro I, Freeman T. Covalent attachment of P15 peptide to titanium surfaces enhances cell attachment, spreading, and osteogenic gene expression. J Orthop Res. 2012 Oct; 30(10):1626-33.
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Zhang W, Alt-Holland A, Margulis A, Shamis Y, Fusenig NE, Rodeck U, Garlick JA. E-cadherin loss promotes the initiation of squamous cell carcinoma invasion through modulation of integrin-mediated adhesion. J Cell Sci. 2006 Jan 15; 119(Pt 2):283-91.
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Risbud MV, Guttapalli A, Albert TJ, Shapiro IM. Hypoxia activates MAPK activity in rat nucleus pulposus cells: regulation of integrin expression and cell survival. Spine (Phila Pa 1976). 2005 Nov 15; 30(22):2503-9.
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Li TT, Larrucea S, Souza S, Leal SM, L?pez JA, Rubin EM, Nieswandt B, Bray PF. Genetic variation responsible for mouse strain differences in integrin alpha 2 expression is associated with altered platelet responses to collagen. Blood. 2004 May 01; 103(9):3396-402.
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Aplin AE, Short SM, Juliano RL. Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains. J Biol Chem. 1999 Oct 29; 274(44):31223-8.