Deoxyribonuclease IV (Phage T4-Induced)
"Deoxyribonuclease IV (Phage T4-Induced)" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the endonucleolytic cleavage of phosphodiester bonds at purinic or apyrimidinic sites (AP-sites) to produce 5'-Phosphooligonucleotide end products. The enzyme prefers single-stranded DNA (ssDNA) and was formerly classified as EC 3.1.4.30.
| Descriptor ID |
D043223
|
| MeSH Number(s) |
D08.811.277.352.335.350.275
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Deoxyribonuclease IV (Phage T4-Induced)".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonuclease IV (Phage T4-Induced)".
This graph shows the total number of publications written about "Deoxyribonuclease IV (Phage T4-Induced)" by people in this website by year, and whether "Deoxyribonuclease IV (Phage T4-Induced)" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2000 | 0 | 3 | 3 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Deoxyribonuclease IV (Phage T4-Induced)" by people in Profiles.
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Puri RV, Singh N, Gupta RK, Tyagi AK. Endonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damage. PLoS One. 2013; 8(8):e71535.
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Nicolas E, Beggs JM, Taraschi TF. Gelonin is an unusual DNA glycosylase that removes adenine from single-stranded DNA, normal base pairs and mismatches. J Biol Chem. 2000 Oct 06; 275(40):31399-406.
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Haltiwanger BM, Matsumoto Y, Nicolas E, Dianov GL, Bohr VA, Taraschi TF. DNA base excision repair in human malaria parasites is predominantly by a long-patch pathway. Biochemistry. 2000 Feb 01; 39(4):763-72.
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Haltiwanger BM, Karpinich NO, Taraschi TF. Characterization of class II apurinic/apyrimidinic endonuclease activities in the human malaria parasite, Plasmodium falciparum. Biochem J. 2000 Jan 01; 345 Pt 1:85-9.
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Nicolas E, Beggs JM, Haltiwanger BM, Taraschi TF. A new class of DNA glycosylase/apurinic/apyrimidinic lyases that act on specific adenines in single-stranded DNA. J Biol Chem. 1998 Jul 03; 273(27):17216-20.