"Aryldialkylphosphatase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme which catalyzes the hydrolysis of an aryl-dialkyl phosphate to form dialkyl phosphate and an aryl alcohol. It can hydrolyze a broad spectrum of organophosphate substrates and a number of aromatic carboxylic acid esters. It may also mediate an enzymatic protection of LOW DENSITY LIPOPROTEINS against oxidative modification and the consequent series of events leading to ATHEROMA formation. The enzyme was previously regarded to be identical with Arylesterase (EC 3.1.1.2).
Descriptor ID |
D043303
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MeSH Number(s) |
D08.811.277.352.660.500
|
Concept/Terms |
Aryldialkylphosphatase- Aryldialkylphosphatase
- Arylalkylphosphatase
- Homocysteine Thiolactone Hydrolase
- Hydrolase, Homocysteine Thiolactone
- Thiolactone Hydrolase, Homocysteine
- OPA Anhydrase
- Anhydrase, OPA
- Paraoxonase
- Organophosphorus Acid Anhydrase
- Acid Anhydrase, Organophosphorus
- Anhydrase, Organophosphorus Acid
- Organophosphorus Acid Anhydrolase
- Acid Anhydrolase, Organophosphorus
- Anhydrolase, Organophosphorus Acid
- Organophosphorus Acid Hydrolase
- Acid Hydrolase, Organophosphorus
- Hydrolase, Organophosphorus Acid
- Organophosphorus Hydrolase
- Hydrolase, Organophosphorus
- Aryl-dialkyl Phosphatase
- Aryl dialkyl Phosphatase
- Phosphatase, Aryl-dialkyl
- OPH Enzyme
- Enzyme, OPH
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Below are MeSH descriptors whose meaning is more general than "Aryldialkylphosphatase".
Below are MeSH descriptors whose meaning is more specific than "Aryldialkylphosphatase".
This graph shows the total number of publications written about "Aryldialkylphosphatase" by people in this website by year, and whether "Aryldialkylphosphatase" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2001 | 0 | 1 | 1 |
2004 | 1 | 0 | 1 |
2005 | 0 | 1 | 1 |
2006 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Aryldialkylphosphatase" by people in Profiles.
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Trieb M, Kornej J, Knuplez E, Hindricks G, Thiele H, Sommer P, Scharnagl H, Dagres N, Dinov B, Bollmann A, Husser D, Marsche G, Buettner P. Atrial fibrillation is associated with alterations in HDL function, metabolism, and particle number. Basic Res Cardiol. 2019 05 08; 114(4):27.
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Manning PJ, Jong SA, Ryalls AR, Sutherland WH. Paraoxonase 1 activity in chylomicrons and VLDL: the effect of type 2 diabetes and meals rich in saturated fat and oleic acid. Lipids. 2012 Mar; 47(3):259-67.
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Capri M, Salvioli S, Sevini F, Valensin S, Celani L, Monti D, Pawelec G, De Benedictis G, Gonos ES, Franceschi C. The genetics of human longevity. Ann N Y Acad Sci. 2006 May; 1067:252-63.
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Franceschi C, Olivieri F, Marchegiani F, Cardelli M, Cavallone L, Capri M, Salvioli S, Valensin S, De Benedictis G, Di Iorio A, Caruso C, Paolisso G, Monti D. Genes involved in immune response/inflammation, IGF1/insulin pathway and response to oxidative stress play a major role in the genetics of human longevity: the lesson of centenarians. Mech Ageing Dev. 2005 Feb; 126(2):351-61.
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Yeung DT, Josse D, Nicholson JD, Khanal A, McAndrew CW, Bahnson BJ, Lenz DE, Cerasoli DM. Structure/function analyses of human serum paraoxonase (HuPON1) mutants designed from a DFPase-like homology model. Biochim Biophys Acta. 2004 Oct 1; 1702(1):67-77.
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Sutherland WH, Manning PJ, de Jong SA, Allum AR, Jones SD, Williams SM. Hormone-replacement therapy increases serum paraoxonase arylesterase activity in diabetic postmenopausal women. Metabolism. 2001 Mar; 50(3):319-24.