"Receptor, Adenosine A3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of ADENOSINE RECEPTOR that is found expressed in a variety of locations including the BRAIN and endocrine tissues. The receptor is generally considered to be coupled to the GI, INHIBITORY G-PROTEIN which causes down regulation of CYCLIC AMP.
| Descriptor ID |
D043684
|
| MeSH Number(s) |
D12.776.543.750.695.700.700.300 D12.776.543.750.720.700.700.300
|
| Concept/Terms |
Receptor, Adenosine A3- Receptor, Adenosine A3
- A3 Receptor, Adenosine
- Adenosine A3 Receptor
- Adenosine A3 Receptors
- A3 Receptors, Adenosine
- Receptors, Adenosine A3
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Adenosine A3".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Purinergic [D12.776.543.750.695.700]
- Receptors, Purinergic P1 [D12.776.543.750.695.700.700]
- Receptor, Adenosine A3 [D12.776.543.750.695.700.700.300]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Purinergic [D12.776.543.750.720.700]
- Receptors, Purinergic P1 [D12.776.543.750.720.700.700]
- Receptor, Adenosine A3 [D12.776.543.750.720.700.700.300]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Adenosine A3".
This graph shows the total number of publications written about "Receptor, Adenosine A3" by people in this website by year, and whether "Receptor, Adenosine A3" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Receptor, Adenosine A3" by people in Profiles.
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Naik SD, Kim M, Choi J, Kim G, Woo Kim S, Aswar VR, Tripathi SK, Gaikwad V, Yu J, Shin Jeong L. Exploring C2 and N6 Substituent Effects on Truncated 4'-Thioadenosine Derivatives as Dual A2A and A3 Adenosine Receptor Ligands. ChemMedChem. 2025 Feb 16; 20(4):e202400575.
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Kim M, Naik SD, Jarhad DB, Aswar VR, Tripathi SK, Aslam MA, Huh JY, Jeong LS. Stereochemical influence of 4'-methyl substitutions on truncated 4'-thioadenosine derivatives: Impact on A3 adenosine receptor binding and antagonism. Bioorg Chem. 2024 12; 153:107901.
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Pak ES, Jeong LS, Hou X, Tripathi SK, Lee J, Ha H. Dual Actions of A2A and A3 Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice. Int J Mol Sci. 2021 May 26; 22(11).
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Minacapelli CD, Bajpai M, Geng X, Van Gurp J, Poplin E, Amenta PS, Brant SR, Das KM. miR-206 as a Biomarker for Response to Mesalamine Treatment in Ulcerative Colitis. Inflamm Bowel Dis. 2019 01 01; 25(1):78-84.
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Hua X, Chason KD, Fredholm BB, Deshpande DA, Penn RB, Tilley SL. Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells. J Allergy Clin Immunol. 2008 Jul; 122(1):107-13, 113.e1-7.
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Berger BW, Garc?a RY, Lenhoff AM, Kaler EW, Robinson CR. Relating surfactant properties to activity and solubilization of the human adenosine a3 receptor. Biophys J. 2005 Jul; 89(1):452-64.
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Santini F, Penn RB, Gagnon AW, Benovic JL, Keen JH. Selective recruitment of arrestin-3 to clathrin coated pits upon stimulation of G protein-coupled receptors. J Cell Sci. 2000 Jul; 113 ( Pt 13):2463-70.