Receptor, Serotonin, 5-HT2A
"Receptor, Serotonin, 5-HT2A" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.
| Descriptor ID |
D044402
|
| MeSH Number(s) |
D12.776.543.750.670.800.200.100 D12.776.543.750.695.800.200.100 D12.776.543.750.720.850.200.100
|
| Concept/Terms |
Receptor, Serotonin, 5-HT2A- Receptor, Serotonin, 5-HT2A
- 5-HT2A Receptor
- 5 HT2A Receptor
- Receptor, 5-HT2A
- Serotonin 2A Receptors
- Receptors, Serotonin 2A
- Serotonin 2A Receptor
- 5-HT(2A) Receptor
- Receptor, Serotonin 2A
|
Below are MeSH descriptors whose meaning is more general than "Receptor, Serotonin, 5-HT2A".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Biogenic Amine [D12.776.543.750.670]
- Receptors, Serotonin [D12.776.543.750.670.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.670.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.670.800.200.100]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Serotonin [D12.776.543.750.695.800]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.695.800.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.695.800.200.100]
- Receptors, Neurotransmitter [D12.776.543.750.720]
- Receptors, Serotonin [D12.776.543.750.720.850]
- Receptors, Serotonin, 5-HT2 [D12.776.543.750.720.850.200]
- Receptor, Serotonin, 5-HT2A [D12.776.543.750.720.850.200.100]
Below are MeSH descriptors whose meaning is more specific than "Receptor, Serotonin, 5-HT2A".
This graph shows the total number of publications written about "Receptor, Serotonin, 5-HT2A" by people in this website by year, and whether "Receptor, Serotonin, 5-HT2A" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Receptor, Serotonin, 5-HT2A" by people in Profiles.
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Sun-Edelstein C, Tepper SJ, Shapiro RE. Drug-induced serotonin syndrome: a review. Expert Opin Drug Saf. 2008 Sep; 7(5):587-96.
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Oquendo MA, Russo SA, Underwood MD, Kassir SA, Ellis SP, Mann JJ, Arango V. Higher postmortem prefrontal 5-HT2A receptor binding correlates with lifetime aggression in suicide. Biol Psychiatry. 2006 Feb 01; 59(3):235-43.
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Gray JA, Sheffler DJ, Bhatnagar A, Woods JA, Hufeisen SJ, Benovic JL, Roth BL. Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells. Mol Pharmacol. 2001 Nov; 60(5):1020-30.
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Bhatnagar A, Willins DL, Gray JA, Woods J, Benovic JL, Roth BL. The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis. J Biol Chem. 2001 Mar 16; 276(11):8269-77.