"Scleroderma, Diffuse" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A rapid onset form of SYSTEMIC SCLERODERMA with progressive widespread SKIN thickening over the arms, the legs and the trunk, resulting in stiffness and disability.
| Descriptor ID |
D045743
|
| MeSH Number(s) |
C17.300.799.602 C17.800.784.602
|
| Concept/Terms |
Scleroderma, Diffuse- Scleroderma, Diffuse
- Scleroderma, Progressive
- Progressive Scleroderma
- Diffuse Cutaneous Systemic Sclerosis
- Sudden Onset Scleroderma
- Scleroderma, Sudden Onset
- Sclerodermas, Sudden Onset
- Sudden Onset Sclerodermas
- Diffuse Systemic Sclerosis
- Diffuse Systemic Scleroses
- Scleroses, Diffuse Systemic
- Sclerosis, Diffuse Systemic
- Systemic Scleroses, Diffuse
- Systemic Sclerosis, Diffuse
- Diffuse Scleroderma
- Sclerosis, Progressive Systemic
- Progressive Systemic Sclerosis
- Systemic Sclerosis, Progressive
|
Below are MeSH descriptors whose meaning is more general than "Scleroderma, Diffuse".
Below are MeSH descriptors whose meaning is more specific than "Scleroderma, Diffuse".
This graph shows the total number of publications written about "Scleroderma, Diffuse" by people in this website by year, and whether "Scleroderma, Diffuse" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Scleroderma, Diffuse" by people in Profiles.
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Mendoza FA, Lee-Ching C, Jimenez SA. Recurrence of progressive skin involvement following discontinuation or dose reduction of Mycophenolate Mofetil treatment in patients with diffuse Systemic Sclerosis. Semin Arthritis Rheum. 2020 02; 50(1):135-139.
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Piera-Velazquez S, Jimenez SA. Simultaneous inhibition of c-Abl and Src kinases abrogates the exaggerated expression of profibrotic genes in cultured systemic sclerosis dermal fibroblasts. Clin Exp Rheumatol. 2018 Jul-Aug; 36 Suppl 113(4):36-44.
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Kampylafka EI, Alexopoulos H, Dalakas MC, Tzioufas AG. Immunotherapies for Neurological Manifestations in the Context of Systemic Autoimmunity. Neurotherapeutics. 2016 Jan; 13(1):163-78.
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Mendoza FA, Nagle SJ, Lee JB, Jimenez SA. A prospective observational study of mycophenolate mofetil treatment in progressive diffuse cutaneous systemic sclerosis of recent onset. J Rheumatol. 2012 Jun; 39(6):1241-7.
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Hou Y, Rabquer BJ, Gerber ML, Del Galdo F, Jimenez SA, Haines GK, Barr WG, Massa MC, Seibold JR, Koch AE. Junctional adhesion molecule-A is abnormally expressed in diffuse cutaneous systemic sclerosis skin and mediates myeloid cell adhesion. Ann Rheum Dis. 2010 Jan; 69(1):249-54.
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Derk CT, Huaman G, Jimenez SA. A retrospective randomly selected cohort study of D-penicillamine treatment in rapidly progressive diffuse cutaneous systemic sclerosis of recent onset. Br J Dermatol. 2008 May; 158(5):1063-8.
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Verrecchia F, Laboureau J, Verola O, Roos N, Porcher R, Bruneval P, Ertault M, Tiev K, Michel L, Mauviel A, Farge D. Skin involvement in scleroderma--where histological and clinical scores meet. Rheumatology (Oxford). 2007 May; 46(5):833-41.
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Derk CT, Artlett CM, Jimenez SA. Morbidity and mortality of patients diagnosed with systemic sclerosis after the age of 75: a nested case-control study. Clin Rheumatol. 2006 Nov; 25(6):831-4.
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Louneva N, Saitta B, Herrick DJ, Jimenez SA. Transcriptional inhibition of type I collagen gene expression in scleroderma fibroblasts by the antineoplastic drug ecteinascidin 743. J Biol Chem. 2003 Oct 10; 278(41):40400-7.