"Casein Kinase II" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitous casein kinase that is comprised of two distinct catalytic subunits and dimeric regulatory subunit. Casein kinase II has been shown to phosphorylate a large number of substrates, many of which are proteins involved in the regulation of gene expression.
| Descriptor ID |
D047390
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.140.600 D12.776.476.150.600
|
| Concept/Terms |
Casein Kinase II- Casein Kinase II
- Protein Kinase CKII
- Kinase CKII, Protein
- Casein Kinase-2
- Protein Kinase CK2
- Casein Kinase 2
- Casein Kinase TS
|
Below are MeSH descriptors whose meaning is more general than "Casein Kinase II".
Below are MeSH descriptors whose meaning is more specific than "Casein Kinase II".
This graph shows the total number of publications written about "Casein Kinase II" by people in this website by year, and whether "Casein Kinase II" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 1 | 1 | 2 |
| 2015 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Casein Kinase II" by people in Profiles.
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Sato K, Padgaonkar AA, Baker SJ, Cosenza SC, Rechkoblit O, Subbaiah DRCV, Domingo-Domenech J, Bartkowski A, Port ER, Aggarwal AK, Ramana Reddy MV, Irie HY, Reddy EP. Simultaneous CK2/TNIK/DYRK1 inhibition by 108600 suppresses triple negative breast cancer stem cells and chemotherapy-resistant disease. Nat Commun. 2021 08 03; 12(1):4671.
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Pathak HB, Zhou Y, Sethi G, Hirst J, Schilder RJ, Golemis EA, Godwin AK. A Synthetic Lethality Screen Using a Focused siRNA Library to Identify Sensitizers to Dasatinib Therapy for the Treatment of Epithelial Ovarian Cancer. PLoS One. 2015; 10(12):e0144126.
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Akkiraju H, Bonor J, Olli K, Bowen C, Bragdon B, Coombs H, Donahue LR, Duncan R, Nohe A. Systemic injection of CK2.3, a novel peptide acting downstream of bone morphogenetic protein receptor BMPRIa, leads to increased trabecular bone mass. J Orthop Res. 2015 Feb; 33(2):208-15.
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Zhang M, Meng XY, Cui M, Pascal JM, Logothetis DE, Zhang JF. Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex. Nat Chem Biol. 2014 Sep; 10(9):753-9.
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Schumann M, Armen RS. Identification of distant drug off-targets by direct superposition of binding pocket surfaces. PLoS One. 2013; 8(12):e83533.
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Cohen JC, Killeen E, Chander A, Takemaru K, Larson JE, Treharne KJ, Mehta A. Small interfering peptide (siP) for in vivo examination of the developing lung interactonome. Dev Dyn. 2009 Feb; 238(2):386-93.
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Chen-Roetling J, Li Z, Regan RF. Hemoglobin neurotoxicity is attenuated by inhibitors of the protein kinase CK2 independent of heme oxygenase activity. Curr Neurovasc Res. 2008 Aug; 5(3):193-8.
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Alvarez-Arias DA, Campbell KS. Protein kinase C regulates expression and function of inhibitory killer cell Ig-like receptors in NK cells. J Immunol. 2007 Oct 15; 179(8):5281-90.
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Claudio PP, Cui J, Ghafouri M, Mariano C, White MK, Safak M, Sheffield JB, Giordano A, Khalili K, Amini S, Sawaya BE. Cdk9 phosphorylates p53 on serine 392 independently of CKII. J Cell Physiol. 2006 Sep; 208(3):602-12.
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Kim YM, Barak LS, Caron MG, Benovic JL. Regulation of arrestin-3 phosphorylation by casein kinase II. J Biol Chem. 2002 May 10; 277(19):16837-46.