"Saposins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of four homologous sphingolipid activator proteins that are formed from proteolytic cleavage of a common protein precursor molecule referred to as prosaposin.
| Descriptor ID |
D049231
|
| MeSH Number(s) |
D08.211.790.500
|
| Concept/Terms |
Saposin B- Saposin B
- Sphingolipid Activator Protein 1
- Sphingolipid Activator Protein-1
- SAP-1 Sphingolipid Activator
- SAP 1 Sphingolipid Activator
- Sphingolipid Activator, SAP-1
Saposin C- Saposin C
- beta-Glucosidase Stimulating Protein
- beta Glucosidase Stimulating Protein
- Co-beta-Glucosidase
- Co beta Glucosidase
- Sphingolipid Activator Protein 2
- Gaucher Activator Protein
- Glucosylceramidase Activator
- SAP-C Protein
- SAP C Protein
- beta-Glucosidase Activator Protein
- beta Glucosidase Activator Protein
- Coglucosidase
|
Below are MeSH descriptors whose meaning is more general than "Saposins".
Below are MeSH descriptors whose meaning is more specific than "Saposins".
This graph shows the total number of publications written about "Saposins" by people in this website by year, and whether "Saposins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Saposins" by people in Profiles.
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Calderwood L, Wenger DA, Matern D, Dahmoush H, Watiker V, Lee C. Rare Saposin A deficiency: Novel variant and psychosine analysis. Mol Genet Metab. 2020 02; 129(2):161-164.
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Rafi MA, de Gala G, Zhang XL, Wenger DA. Mutational analysis in a patient with a variant form of Gaucher disease caused by SAP-2 deficiency. Somat Cell Mol Genet. 1993 Jan; 19(1):1-7.
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Rafi MA, Amini S, Zhang XL, Wenger DA. Correction of sulfatide metabolism after transfer of prosaposin cDNA to cultured cells from a patient with SAP-1 deficiency. Am J Hum Genet. 1992 Jun; 50(6):1252-8.
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Zhang XL, Rafi MA, DeGala G, Wenger DA. The mechanism for a 33-nucleotide insertion in mRNA causing sphingolipid activator protein (SAP-1)-deficient metachromatic leukodystrophy. Hum Genet. 1991 Jun; 87(2):211-5.
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Zhang XL, Rafi MA, DeGala G, Wenger DA. Insertion in the mRNA of a metachromatic leukodystrophy patient with sphingolipid activator protein-1 deficiency. Proc Natl Acad Sci U S A. 1990 Feb; 87(4):1426-30.
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Rafi MA, Zhang XL, DeGala G, Wenger DA. Detection of a point mutation in sphingolipid activator protein-1 mRNA in patients with a variant form of metachromatic leukodystrophy. Biochem Biophys Res Commun. 1990 Jan 30; 166(2):1017-23.