STAT1 Transcription Factor

"STAT1 Transcription Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A signal transducer and activator of transcription that mediates cellular responses to INTERFERONS. Stat1 interacts with P53 TUMOR SUPPRESSOR PROTEIN and regulates expression of GENES involved in growth control and APOPTOSIS.

Descriptor ID	D050794
MeSH Number(s)	D12.644.360.024.303.500.500 D12.644.360.024.342.100 D12.776.157.057.061.500.500 D12.776.157.057.186.100 D12.776.260.513.249.500 D12.776.476.024.386.500.500 D12.776.476.024.430.100 D12.776.930.354.249.500 D12.776.930.840.100
Concept/Terms	STAT1 Transcription Factor STAT1 Transcription Factor Transcription Factor, STAT1 Transcription Factor STAT91 Gamma-Activated Factor, 91 kDa Gamma Activated Factor, 91 kDa STAT-91 Transcription Factor STAT 91 Transcription Factor Transcription Factor, STAT-91 STAT-91 Protein STAT 91 Protein STAT91 Transcription Factor Transcription Factor, STAT91 STAT1 Protein Signal Transducer and Activator of Transcription 1

Below are MeSH descriptors whose meaning is more general than "STAT1 Transcription Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Adaptor Proteins, Signal Transducing [D12.644.360.024]
Interferon-Stimulated Gene Factor 3 [D12.644.360.024.303]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.644.360.024.303.500]
STAT1 Transcription Factor [D12.644.360.024.303.500.500]
STAT Transcription Factors [D12.644.360.024.342]
STAT1 Transcription Factor [D12.644.360.024.342.100]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
Adaptor Proteins, Signal Transducing [D12.776.157.057]
Interferon-Stimulated Gene Factor 3 [D12.776.157.057.061]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.157.057.061.500]
STAT1 Transcription Factor [D12.776.157.057.061.500.500]
STAT Transcription Factors [D12.776.157.057.186]
STAT1 Transcription Factor [D12.776.157.057.186.100]
DNA-Binding Proteins [D12.776.260]
Interferon-Stimulated Gene Factor 3 [D12.776.260.513]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.260.513.249]
STAT1 Transcription Factor [D12.776.260.513.249.500]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Adaptor Proteins, Signal Transducing [D12.776.476.024]
Interferon-Stimulated Gene Factor 3 [D12.776.476.024.386]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.476.024.386.500]
STAT1 Transcription Factor [D12.776.476.024.386.500.500]
STAT Transcription Factors [D12.776.476.024.430]
STAT1 Transcription Factor [D12.776.476.024.430.100]
Transcription Factors [D12.776.930]
Interferon-Stimulated Gene Factor 3 [D12.776.930.354]
Interferon-Stimulated Gene Factor 3, alpha Subunit [D12.776.930.354.249]
STAT1 Transcription Factor [D12.776.930.354.249.500]
STAT Transcription Factors [D12.776.930.840]
STAT1 Transcription Factor [D12.776.930.840.100]

Below are MeSH descriptors whose meaning is related to "STAT1 Transcription Factor".

Below are MeSH descriptors whose meaning is more specific than "STAT1 Transcription Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "STAT1 Transcription Factor" by people in this website by year, and whether "STAT1 Transcription Factor" was a major or minor topic of these publications.

Bar chart showing 40 publications over 20 distinct years, with a maximum of 4 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	1	1
1998	0	1	1
2000	0	2	2
2004	0	2	2
2005	0	1	1
2007	1	2	3
2008	1	1	2
2009	1	3	4
2010	1	1	2
2011	1	2	3
2012	2	1	3
2013	0	2	2
2014	0	1	1
2015	3	0	3
2016	2	1	3
2017	0	1	1
2018	2	0	2
2020	2	0	2
2021	1	0	1
2022	0	1	1

Below are the most recent publications written about "STAT1 Transcription Factor" by people in Profiles.

Dong Z, Zhan T, Sun H, Wang J, Duan G, Zhang Y, Chen Y, Huang Y, Xu S. Astrocytic ERK/STAT1 Signaling Contributes to Maintenance of Stress-Related Visceral Hypersensitivity in Rats. J Pain. 2022 11; 23(11):1973-1988.

View in: PubMed
Naranjo NM, Salem I, Harris MA, Languino LR. IFIT3 (interferon induced protein with tetratricopeptide repeats 3) modulates STAT1 expression in small extracellular vesicles. Biochem J. 2021 11 12; 478(21):3905-3921.

View in: PubMed
Chodisetti SB, Fike AJ, Domeier PP, Schell SL, Mockus TE, Choi NM, Corradetti C, Hou B, Atkins HM, Caricchio R, Decker T, Lukacher AE, Olsen N, Rahman ZSM. Serine Phosphorylation of the STAT1 Transactivation Domain Promotes Autoreactive B Cell and Systemic Autoimmunity Development. J Immunol. 2020 05 15; 204(10):2641-2650.

View in: PubMed
Safavi F, Thome R, Li Z, Wang L, Rasouli J, Ciric B, Zhang GX, Rostami A. A serine protease inhibitor induces type 1 regulatory T cells through IFN-?/STAT1 signaling. Cell Mol Immunol. 2020 09; 17(9):1004-1006.

View in: PubMed
Thome R, Bonfanti AP, Rasouli J, Mari ER, Zhang GX, Rostami A, Verinaud L. Chloroquine-treated dendritic cells require STAT1 signaling for their tolerogenic activity. Eur J Immunol. 2018 07; 48(7):1228-1234.

View in: PubMed
Lu H, Bowler N, Harshyne LA, Craig Hooper D, Krishn SR, Kurtoglu S, Fedele C, Liu Q, Tang HY, Kossenkov AV, Kelly WK, Wang K, Kean RB, Weinreb PH, Yu L, Dutta A, Fortina P, Ertel A, Stanczak M, Forsberg F, Gabrilovich DI, Speicher DW, Altieri DC, Languino LR. Exosomal av?6 integrin is required for monocyte M2 polarization in prostate cancer. Matrix Biol. 2018 09; 70:20-35.

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Miller KD, Rall GF. What Kaplan-Meier survival curves don't tell us about CNS disease. J Neuroimmunol. 2017 07 15; 308:25-29.

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Tao Y, Zhang X, Markovic-Plese S. Toll-like receptor (TLR)7 and TLR9 agonists enhance interferon (IFN) beta-1a's immunoregulatory effects on B cells in patients with relapsing-remitting multiple sclerosis (RRMS). J Neuroimmunol. 2016 09 15; 298:181-8.

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Lerchenm?ller C, Hei?enberg J, Damilano F, Bezzeridis VJ, Kr?mer I, Bochaton-Piallat ML, Hirschberg K, Busch M, Katus HA, Peppel K, Rosenzweig A, Busch H, Boerries M, Most P. S100A6 Regulates Endothelial Cell Cycle Progression by Attenuating Antiproliferative Signal Transducers and Activators of Transcription 1 Signaling. Arterioscler Thromb Vasc Biol. 2016 09; 36(9):1854-67.

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Domeier PP, Chodisetti SB, Soni C, Schell SL, Elias MJ, Wong EB, Cooper TK, Kitamura D, Rahman ZS. IFN-? receptor and STAT1 signaling in B cells are central to spontaneous germinal center formation and autoimmunity. J Exp Med. 2016 05 02; 213(5):715-32.

View in: PubMed

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