"Shal Potassium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A shaker subfamily of potassium channels that participate in transient outward potassium currents by activating at subthreshold MEMBRANE POTENTIALS, inactivating rapidly, and recovering from inactivation quickly.
| Descriptor ID |
D051672
|
| MeSH Number(s) |
D12.776.157.530.400.600.900.500.625 D12.776.543.550.450.750.900.500.625 D12.776.543.585.400.750.900.624.625
|
| Concept/Terms |
Shal Potassium Channels- Shal Potassium Channels
- Potassium Channels, Shal
- Kv4 Potassium Channels
- Potassium Channels, Kv4
Kv4.3 Potassium Channel- Kv4.3 Potassium Channel
- Potassium Channel, Kv4.3
- KCND3 Potassium Channel
- Potassium Channel, KCND3
Kv4.1 Potassium Channel- Kv4.1 Potassium Channel
- Potassium Channel, Kv4.1
- KCND1 Potassium Channel
- Potassium Channel, KCND1
Kv4.2 Potassium Channel- Kv4.2 Potassium Channel
- Potassium Channel, Kv4.2
- KCND2 Potassium Channel
- Potassium Channel, KCND2
|
Below are MeSH descriptors whose meaning is more general than "Shal Potassium Channels".
Below are MeSH descriptors whose meaning is more specific than "Shal Potassium Channels".
This graph shows the total number of publications written about "Shal Potassium Channels" by people in this website by year, and whether "Shal Potassium Channels" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 2 | 2 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2006 | 2 | 0 | 2 |
| 2007 | 2 | 0 | 2 |
| 2008 | 4 | 0 | 4 |
| 2009 | 3 | 2 | 5 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 2 | 0 | 2 |
| 2013 | 1 | 1 | 2 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Shal Potassium Channels" by people in Profiles.
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Ye D, Zhou W, Hamrick SK, Tester DJ, Kim CSJ, Barajas-Martinez H, Hu D, Giudicessi JR, Antzelevitch C, Ackerman MJ. Acacetin, a Potent Transient Outward Current Blocker, May Be a Novel Therapeutic for KCND3-Encoded Kv4.3 Gain-of-Function-Associated J-Wave Syndromes. Circ Genom Precis Med. 2022 Oct; 15(5):e003238.
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Clatot J, Neyroud N, Cox R, Souil C, Huang J, Guicheney P, Antzelevitch C. Inter-Regulation of Kv4.3 and Voltage-Gated Sodium Channels Underlies Predisposition to Cardiac and Neuronal Channelopathies. Int J Mol Sci. 2020 Jul 17; 21(14).
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Fineberg JD, Szanto TG, Panyi G, Covarrubias M. Closed-state inactivation involving an internal gate in Kv4.1 channels modulates pore blockade by intracellular quaternary ammonium ions. Sci Rep. 2016 08 09; 6:31131.
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Covarrubias M. Dipeptidyl-peptidase-like proteins cast in a new role: enabling scorpion toxin block of A-type K+ channels. J Physiol. 2013 May 15; 591(10):2373-4.
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Cordeiro JM, Nesterenko VV, Sicouri S, Goodrow RJ, Treat JA, Desai M, Wu Y, Doss MX, Antzelevitch C, Di Diego JM. Identification and characterization of a transient outward K+ current in human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2013 Jul; 60:36-46.
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Fineberg JD, Ritter DM, Covarrubias M. Modeling-independent elucidation of inactivation pathways in recombinant and native A-type Kv channels. J Gen Physiol. 2012 Nov; 140(5):513-27.
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Giudicessi JR, Ye D, Kritzberger CJ, Nesterenko VV, Tester DJ, Antzelevitch C, Ackerman MJ. Novel mutations in the KCND3-encoded Kv4.3 K+ channel associated with autopsy-negative sudden unexplained death. Hum Mutat. 2012 Jun; 33(6):989-97.
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Giudicessi JR, Ye D, Tester DJ, Crotti L, Mugione A, Nesterenko VV, Albertson RM, Antzelevitch C, Schwartz PJ, Ackerman MJ. Transient outward current (I(to)) gain-of-function mutations in the KCND3-encoded Kv4.3 potassium channel and Brugada syndrome. Heart Rhythm. 2011 Jul; 8(7):1024-32.
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B?hring R, Covarrubias M. Mechanisms of closed-state inactivation in voltage-gated ion channels. J Physiol. 2011 Feb 01; 589(Pt 3):461-79.
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Jerng HH, Dougherty K, Covarrubias M, Pfaffinger PJ. A novel N-terminal motif of dipeptidyl peptidase-like proteins produces rapid inactivation of KV4.2 channels by a pore-blocking mechanism. Channels (Austin). 2009 Nov; 3(6):448-61.