Sterol Regulatory Element Binding Protein 1
"Sterol Regulatory Element Binding Protein 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sterol regulatory element binding protein that regulates expression of GENES involved in FATTY ACIDS metabolism and LIPOGENESIS. Two major isoforms of the protein exist due to ALTERNATIVE SPLICING.
| Descriptor ID |
D051780
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| MeSH Number(s) |
D12.776.260.103.500.750.500 D12.776.260.108.092.750.500 D12.776.930.125.500.750.500 D12.776.930.127.092.750.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Sterol Regulatory Element Binding Protein 1".
Below are MeSH descriptors whose meaning is more specific than "Sterol Regulatory Element Binding Protein 1".
This graph shows the total number of publications written about "Sterol Regulatory Element Binding Protein 1" by people in this website by year, and whether "Sterol Regulatory Element Binding Protein 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2012 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sterol Regulatory Element Binding Protein 1" by people in Profiles.
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Al-Zoubi M, Chipitsyna G, Saxena S, Sarosiek K, Gandhi A, Kang CY, Relles D, Andrelsendecki J, Hyslop T, Yeo CJ, Arafat HA. Overexpressing TNF-alpha in pancreatic ductal adenocarcinoma cells and fibroblasts modifies cell survival and reduces fatty acid synthesis via downregulation of sterol regulatory element binding protein-1 and activation of acetyl CoA carboxylase. J Gastrointest Surg. 2014 Feb; 18(2):257-68; discussion 268.
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Li W, Tai Y, Zhou J, Gu W, Bai Z, Zhou T, Zhong Z, McCue PA, Sang N, Ji JY, Kong B, Jiang J, Wang C. Repression of endometrial tumor growth by targeting SREBP1 and lipogenesis. Cell Cycle. 2012 Jun 15; 11(12):2348-58.
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Le Hellard S, Theisen FM, Haberhausen M, Raeder MB, Fern? J, Gebhardt S, Hinney A, Remschmidt H, Krieg JC, Mehler-Wex C, N?then MM, Hebebrand J, Steen VM. Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects? Mol Psychiatry. 2009 Mar; 14(3):308-17.
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Zhou RH, Pesant S, Cohn HI, Eckhart AD. Enhanced sterol response element-binding protein in postintervention restenotic blood vessels plays an important role in vascular smooth muscle proliferation. Life Sci. 2008 Jan 16; 82(3-4):174-81.
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Frank PG, Cheung MW, Pavlides S, Llaverias G, Park DS, Lisanti MP. Caveolin-1 and regulation of cellular cholesterol homeostasis. Am J Physiol Heart Circ Physiol. 2006 Aug; 291(2):H677-86.
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Frank PG, Galbiati F, Volonte D, Razani B, Cohen DE, Marcel YL, Lisanti MP. Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins. Am J Physiol Cell Physiol. 2001 May; 280(5):C1204-14.