Interleukin-4 Receptor alpha Subunit
"Interleukin-4 Receptor alpha Subunit" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A receptor subunit that is a component of the TYPE I INTERLEUKIN-4 RECEPTOR and the TYPE II INTERLEUKIN-4 RECEPTOR. It signals through interaction of its cytoplasmic domain with JANUS KINASES such as JANUS KINASE 1.
| Descriptor ID |
D053662
|
| MeSH Number(s) |
D12.776.543.750.705.852.420.360.300.200 D12.776.543.750.705.852.420.360.600.200 D12.776.543.750.705.852.420.600.800.200
|
| Concept/Terms |
Interleukin-4 Receptor alpha Subunit- Interleukin-4 Receptor alpha Subunit
- Interleukin 4 Receptor alpha Subunit
- Antigens, CD124
- CD124 Antigens
- Interleukin-4 Receptor alpha Chain
- Interleukin 4 Receptor alpha Chain
- alpha-subunit, Receptor, Interleukin-4
- Interleukin-4 Receptors alpha
- Interleukin 4 Receptors alpha
- Receptors alpha, Interleukin-4
- Receptor, Interleukin-4, alpha Subunit
- CD124 Antigen
- Antigen, CD124
|
Below are MeSH descriptors whose meaning is more general than "Interleukin-4 Receptor alpha Subunit".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Interleukin [D12.776.543.750.705.852.420]
- Receptors, Interleukin-4 [D12.776.543.750.705.852.420.360]
- Receptors, Interleukin-4, Type I [D12.776.543.750.705.852.420.360.300]
- Interleukin-4 Receptor alpha Subunit [D12.776.543.750.705.852.420.360.300.200]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.360.600]
- Interleukin-4 Receptor alpha Subunit [D12.776.543.750.705.852.420.360.600.200]
- Receptors, Interleukin-13 [D12.776.543.750.705.852.420.600]
- Receptors, Interleukin-4, Type II [D12.776.543.750.705.852.420.600.800]
- Interleukin-4 Receptor alpha Subunit [D12.776.543.750.705.852.420.600.800.200]
Below are MeSH descriptors whose meaning is more specific than "Interleukin-4 Receptor alpha Subunit".
This graph shows the total number of publications written about "Interleukin-4 Receptor alpha Subunit" by people in this website by year, and whether "Interleukin-4 Receptor alpha Subunit" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Interleukin-4 Receptor alpha Subunit" by people in Profiles.
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Li Z, Radin A, Li M, Hamilton JD, Kajiwara M, Davis JD, Takahashi Y, Hasegawa S, Ming JE, DiCioccio AT, Li Y, Kovalenko P, Lu Q, Ortemann-Renon C, Ardeleanu M, Swanson BN. Pharmacokinetics, Pharmacodynamics, Safety, and Tolerability of Dupilumab in Healthy Adult Subjects. Clin Pharmacol Drug Dev. 2020 08; 9(6):742-755.
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Hirano I, Dellon ES, Hamilton JD, Collins MH, Peterson K, Chehade M, Schoepfer AM, Safroneeva E, Rothenberg ME, Falk GW, Assouline-Dayan Y, Zhao Q, Chen Z, Swanson BN, Pirozzi G, Mannent L, Graham NMH, Akinlade B, Stahl N, Yancopoulos GD, Radin A. Efficacy of Dupilumab in a Phase 2 Randomized Trial of Adults With Active Eosinophilic Esophagitis. Gastroenterology. 2020 01; 158(1):111-122.e10.
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Wermeling F, Anthony RM, Brombacher F, Ravetch JV. Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13487-91.
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Karras JG, Crosby JR, Guha M, Tung D, Miller DA, Gaarde WA, Geary RS, Monia BP, Gregory SA. Anti-inflammatory activity of inhaled IL-4 receptor-alpha antisense oligonucleotide in mice. Am J Respir Cell Mol Biol. 2007 Mar; 36(3):276-85.