Dual Specificity Phosphatase 1
"Dual Specificity Phosphatase 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dual specificity phosphatase subtype that plays a role in intracellular signal transduction by inactivating MITOGEN-ACTIVATED PROTEIN KINASES. It has specificity for P38 MITOGEN-ACTIVATED PROTEIN KINASES and JNK MITOGEN-ACTIVATED PROTEIN KINASES.
| Descriptor ID |
D054638
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| MeSH Number(s) |
D08.811.277.352.650.587.200 D08.811.277.352.650.625.225.200 D08.811.277.352.650.775.250.200 D08.811.641.755.200 D12.644.360.268.200 D12.644.360.445.100 D12.776.476.268.200 D12.776.476.445.200
|
| Concept/Terms |
Dual Specificity Phosphatase 1- Dual Specificity Phosphatase 1
- CL100 Phosphatase
- Phosphatase, CL100
- Externally Regulated Phosphatase (ERP)
- MKP-1 Phosphatase
- MKP 1 Phosphatase
- Phosphatase, MKP-1
- MAP Phosphatase-1
- MAP Phosphatase 1
- Phosphatase-1, MAP
- MAPK Phosphatase
- Phosphatase, MAPK
- Mitogen-Activated Protein Phosphatase-1
- Mitogen Activated Protein Phosphatase 1
- Phosphatase-1, Mitogen-Activated Protein
- Protein Phosphatase-1, Mitogen-Activated
- 3CH134 Phosphatase
- Phosphatase, 3CH134
- Map Kinase Phosphatase 1
|
Below are MeSH descriptors whose meaning is more general than "Dual Specificity Phosphatase 1".
Below are MeSH descriptors whose meaning is more specific than "Dual Specificity Phosphatase 1".
This graph shows the total number of publications written about "Dual Specificity Phosphatase 1" by people in this website by year, and whether "Dual Specificity Phosphatase 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Dual Specificity Phosphatase 1" by people in Profiles.
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de Leeuw R, McNair C, Schiewer MJ, Neupane NP, Brand LJ, Augello MA, Li Z, Cheng LC, Yoshida A, Courtney SM, Hazard ES, Hardiman G, Hussain MH, Diehl JA, Drake JM, Kelly WK, Knudsen KE. MAPK Reliance via Acquired CDK4/6 Inhibitor Resistance in Cancer. Clin Cancer Res. 2018 09 01; 24(17):4201-4214.
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Farwell SL, Kanyi D, Hamel M, Slee JB, Miller EA, Cipolle MD, Lowe-Krentz LJ. Heparin Decreases in Tumor Necrosis Factor a (TNFa)-induced Endothelial Stress Responses Require Transmembrane Protein 184A and Induction of Dual Specificity Phosphatase 1. J Biol Chem. 2016 Mar 04; 291(10):5342-54.
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Gavrila A, Chachi L, Tliba O, Brightling C, Amrani Y. Effect of the plant derivative Compound A on the production of corticosteroid-resistant chemokines in airway smooth muscle cells. Am J Respir Cell Mol Biol. 2015 Nov; 53(5):728-37.
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Codony-Servat J, Tapia MA, Bosch M, Oliva C, Domingo-Domenech J, Mellado B, Rolfe M, Ross JS, Gascon P, Rovira A, Albanell J. Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells. Mol Cancer Ther. 2006 Mar; 5(3):665-75.
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Abrams MT, Robertson NM, Litwack G, Wickstrom E. Evaluation of glucocorticoid sensitivity in 697 pre-B acute lymphoblastic leukemia cells after overexpression or silencing of MAP kinase phosphatase-1. J Cancer Res Clin Oncol. 2005 Jun; 131(6):347-54.