Protein Interaction Domains and Motifs

"Protein Interaction Domains and Motifs" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Protein modules with conserved ligand-binding surfaces which mediate specific interaction functions in SIGNAL TRANSDUCTION PATHWAYS and the specific BINDING SITES of their cognate protein LIGANDS.

Descriptor ID	D054730
MeSH Number(s)	G02.111.570.820.709.275.750.500
Concept/Terms	Protein Interaction Domains and Motifs Protein Interaction Domains and Motifs Protein Interaction Motifs Protein Interaction Motifs Motif, Protein Interaction Motifs, Protein Interaction Protein Interaction Motif Binding Motifs, Protein Interaction Protein Interaction Binding Motifs Protein Interaction Domains Protein Interaction Domains Domain, Protein Interaction Domains, Protein Interaction Protein Interaction Domain Protein-Protein Interaction Domains Domain, Protein-Protein Interaction Domains, Protein-Protein Interaction Protein Protein Interaction Domains Protein-Protein Interaction Domain

Below are MeSH descriptors whose meaning is more general than "Protein Interaction Domains and Motifs".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Molecular Structure [G02.111.570]
Molecular Conformation [G02.111.570.820]
Protein Conformation [G02.111.570.820.709]
Protein Structural Elements [G02.111.570.820.709.275]
Protein Domains [G02.111.570.820.709.275.750]
Protein Interaction Domains and Motifs [G02.111.570.820.709.275.750.500]

Below are MeSH descriptors whose meaning is related to "Protein Interaction Domains and Motifs".

Below are MeSH descriptors whose meaning is more specific than "Protein Interaction Domains and Motifs".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Protein Interaction Domains and Motifs" by people in this website by year, and whether "Protein Interaction Domains and Motifs" was a major or minor topic of these publications.

Bar chart showing 60 publications over 15 distinct years, with a maximum of 9 publications in 2013 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2007	0	1	1
2008	0	1	1
2009	0	3	3
2010	1	4	5
2011	2	2	4
2012	1	2	3
2013	2	7	9
2014	0	9	9
2015	1	4	5
2016	1	4	5
2017	0	3	3
2018	0	2	2
2019	1	2	3
2020	1	4	5
2021	0	2	2

Below are the most recent publications written about "Protein Interaction Domains and Motifs" by people in Profiles.

Taftaf R, Liu X, Singh S, Jia Y, Dashzeveg NK, Hoffmann AD, El-Shennawy L, Ramos EK, Adorno-Cruz V, Schuster EJ, Scholten D, Patel D, Zhang Y, Davis AA, Reduzzi C, Cao Y, D'Amico P, Shen Y, Cristofanilli M, Muller WA, Varadan V, Liu H. ICAM1 initiates CTC cluster formation and trans-endothelial migration in lung metastasis of breast cancer. Nat Commun. 2021 08 11; 12(1):4867.

View in: PubMed
Miciaccia M, Belviso BD, Iaselli M, Cingolani G, Ferorelli S, Cappellari M, Loguercio Polosa P, Perrone MG, Caliandro R, Scilimati A. Three-dimensional structure of human cyclooxygenase (hCOX)-1. Sci Rep. 2021 02 22; 11(1):4312.

View in: PubMed
Komolov KE, Sulon SM, Bhardwaj A, van Keulen SC, Duc NM, Laurinavichyute DK, Lou HJ, Turk BE, Chung KY, Dror RO, Benovic JL. Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting. Mol Cell. 2021 01 21; 81(2):323-339.e11.

View in: PubMed
Ripperger TJ, Uhrlaub JL, Watanabe M, Wong R, Castaneda Y, Pizzato HA, Thompson MR, Bradshaw C, Weinkauf CC, Bime C, Erickson HL, Knox K, Bixby B, Parthasarathy S, Chaudhary S, Natt B, Cristan E, El Aini T, Rischard F, Campion J, Chopra M, Insel M, Sam A, Knepler JL, Capaldi AP, Spier CM, Dake MD, Edwards T, Kaplan ME, Scott SJ, Hypes C, Mosier J, Harris DT, LaFleur BJ, Sprissler R, Nikolich-?ugich J, Bhattacharya D. Orthogonal SARS-CoV-2 Serological Assays Enable Surveillance of Low-Prevalence Communities and Reveal Durable Humoral Immunity. Immunity. 2020 11 17; 53(5):925-933.e4.

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Kikuchi M, Sekiya M, Hara N, Miyashita A, Kuwano R, Ikeuchi T, Iijima KM, Nakaya A. Disruption of a RAC1-centred network is associated with Alzheimer's disease pathology and causes age-dependent neurodegeneration. Hum Mol Genet. 2020 03 27; 29(5):817-833.

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Garry CE, Garry RF. Proteomics Computational Analyses Suggest That the Envelope Glycoproteins of Segmented Jingmen Flavi-Like Viruses are Class II Viral Fusion Proteins (b-Penetrenes) with Mucin-Like Domains. Viruses. 2020 02 27; 12(3).

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Washburn HR, Xia NL, Zhou W, Mao YT, Dalva MB. Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility. Nat Commun. 2020 Jan 29; 11(1):570.

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Bournazos S, DiLillo DJ, Goff AJ, Glass PJ, Ravetch JV. Differential requirements for Fc?R engagement by protective antibodies against Ebola virus. Proc Natl Acad Sci U S A. 2019 10 01; 116(40):20054-20062.

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Mercier R, Wolmarans A, Schubert J, Neuweiler H, Johnson JL, LaPointe P. The conserved NxNNWHW motif in Aha-type co-chaperones modulates the kinetics of Hsp90 ATPase stimulation. Nat Commun. 2019 03 20; 10(1):1273.

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Woldeyes MA, Calero-Rubio C, Furst EM, Roberts CJ. Light Scattering to Quantify Protein-Protein Interactions at High Protein Concentrations. Methods Mol Biol. 2019; 2039:23-37.

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