"Phospholipase C beta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphoinositide phospholipase C subtype that is primarily regulated by its association with HETEROTRIMERIC G-PROTEINS. It is structurally related to PHOSPHOLIPASE C DELTA with the addition of C-terminal extension of 400 residues.
| Descriptor ID |
D054799
|
| MeSH Number(s) |
D08.811.277.352.640.700.700.562.500 D12.644.360.571.500 D12.776.476.556.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phospholipase C beta".
Below are MeSH descriptors whose meaning is more specific than "Phospholipase C beta".
This graph shows the total number of publications written about "Phospholipase C beta" by people in this website by year, and whether "Phospholipase C beta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Phospholipase C beta" by people in Profiles.
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De Pascali F, Inoue A, Benovic JL. Diverse pathways in GPCR-mediated activation of Ca2+ mobilization in HEK293 cells. J Biol Chem. 2024 11; 300(11):107882.
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Zhu M, Shahbazi M, Martin A, Zhang C, Sozen B, Borsos M, Mandelbaum RS, Paulson RJ, Mole MA, Esbert M, Titus S, Scott RT, Campbell A, Fishel S, Gradinaru V, Zhao H, Wu K, Chen ZJ, Seli E, de Los Santos MJ, Zernicka Goetz M. Human embryo polarization requires PLC signaling to mediate trophectoderm specification. Elife. 2021 09 27; 10.
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Day PW, Tesmer JJ, Sterne-Marr R, Freeman LC, Benovic JL, Wedegaertner PB. Characterization of the GRK2 binding site of Galphaq. J Biol Chem. 2004 Dec 17; 279(51):53643-52.
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Carman CV, Parent JL, Day PW, Pronin AN, Sternweis PM, Wedegaertner PB, Gilman AG, Benovic JL, Kozasa T. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. J Biol Chem. 1999 Nov 26; 274(48):34483-92.