High-Throughput Screening Assays

"High-Throughput Screening Assays" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Rapid methods of measuring the effects of an agent in a biological or chemical assay. The assay usually involves some form of automation or a way to conduct multiple assays at the same time using sample arrays.

Descriptor ID	D057166
MeSH Number(s)	E05.916.680
Concept/Terms	High-Throughput Screening Assays High-Throughput Screening Assays Assay, High-Throughput Screening High Throughput Screening Assays High-Throughput Screening Assay Screening Assay, High-Throughput Screening Assays, High-Throughput High-Throughput Screening Methods High-Throughput Screening Methods High Throughput Screening Methods High-Throughput Screening Method Methods, High-Throughput Screening Screening Method, High-Throughput Screening Methods, High-Throughput High-Throughput Biological Assays High-Throughput Biological Assays Assay, High-Throughput Biological Assays, High-Throughput Biological Biological Assay, High-Throughput Biological Assays, High-Throughput High Throughput Biological Assays High-Throughput Biological Assay High-Throughput Chemical Assays High-Throughput Chemical Assays Assay, High-Throughput Chemical Assays, High-Throughput Chemical Chemical Assay, High-Throughput Chemical Assays, High-Throughput High Throughput Chemical Assays High-Throughput Chemical Assay

Below are MeSH descriptors whose meaning is more general than "High-Throughput Screening Assays".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Technology, Pharmaceutical [E05.916]
High-Throughput Screening Assays [E05.916.680]

Below are MeSH descriptors whose meaning is related to "High-Throughput Screening Assays".

Below are MeSH descriptors whose meaning is more specific than "High-Throughput Screening Assays".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "High-Throughput Screening Assays" by people in this website by year, and whether "High-Throughput Screening Assays" was a major or minor topic of these publications.

Bar chart showing 53 publications over 16 distinct years, with a maximum of 8 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2009	0	2	2
2010	2	2	4
2011	5	2	7
2012	0	2	2
2013	3	5	8
2014	3	2	5
2015	2	2	4
2016	1	3	4
2017	1	1	2
2018	1	1	2
2019	3	1	4
2020	0	2	2
2021	1	0	1
2023	0	1	1
2024	0	4	4
2025	1	0	1

Below are the most recent publications written about "High-Throughput Screening Assays" by people in Profiles.

Welsh JP, Altern SH, Lyall JY, Burgess S, Rauscher MA, Lenhoff AM, Cramer SM, Williams C. Coupling high-throughput and modeling approaches to streamline early-stage process development for biologics. Biotechnol Prog. 2025 May-Jun; 41(3):e3523.

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Valerie NCK, Sanjiv K, Mortusewicz O, Zhang SM, Alam S, Pires MJ, Stigsdotter H, Rasti A, Langelier MF, Rehling D, Throup A, Purewal-Sidhu O, Desroses M, Onireti J, Wakchaure P, Alml?f I, Bostr?m J, Bevc L, Benzi G, Stenmark P, Pascal JM, Helleday T, Page BDG, Altun M. Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM. Nat Commun. 2024 12 06; 15(1):10347.

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Altern SH, Lyall JY, Welsh JP, Burgess S, Kumar V, Williams C, Lenhoff AM, Cramer SM. High-throughput in silico workflow for optimization and characterization of multimodal chromatographic processes. Biotechnol Prog. 2024 Nov-Dec; 40(6):e3483.

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Reichel F, Goswami R, Girardo S, Guck J. High-throughput viscoelastic characterization of cells in hyperbolic microchannels. Lab Chip. 2024 04 30; 24(9):2440-2453.

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Stueckle TA, Jensen J, Coyle JP, Derk R, Wagner A, Dinu CZ, Kornberg TG, Friend SA, Dozier A, Agarwal S, Gupta RK, Rojanasakul LW. In vitro inflammation and toxicity assessment of pre- and post-incinerated organomodified nanoclays to macrophages using high-throughput screening approaches. Part Fibre Toxicol. 2024 03 21; 21(1):16.

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Sperle K, Pochan DJ, Langhans SA. 3D Hydrogel Cultures for High-Throughput Drug Discovery. Methods Mol Biol. 2023; 2614:369-381.

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Streett H, Charubin K, Papoutsakis ET. Anaerobic fluorescent reporters for cell identification, microbial cell biology and high-throughput screening of microbiota and genomic libraries. Curr Opin Biotechnol. 2021 10; 71:151-163.

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Chua V, Mattei J, Han A, Johnston L, LiPira K, Selig SM, Carvajal RD, Aplin AE, Patel SP. The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019). Clin Cancer Res. 2021 01 01; 27(1):28-33.

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Monnahan PJ, Michno JM, O'Connor C, Brohammer AB, Springer NM, McGaugh SE, Hirsch CN. Using multiple reference genomes to identify and resolve annotation inconsistencies. BMC Genomics. 2020 Apr 08; 21(1):281.

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Farhy C, Hariharan S, Ylanko J, Orozco L, Zeng FY, Pass I, Ugarte F, Forsberg EC, Huang CT, Andrews DW, Terskikh AV. Improving drug discovery using image-based multiparametric analysis of the epigenetic landscape. Elife. 2019 10 22; 8.

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