HEK293 Cells

"HEK293 Cells" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A cell line generated from human embryonic kidney cells that were transformed with human adenovirus type 5.

Descriptor ID	D057809
MeSH Number(s)	A11.251.210.172.750 A11.436.334
Concept/Terms	HEK293 Cells HEK293 Cells Cell, HEK293 Cells, HEK293 HEK293 Cell 293T Cells 293T Cell Cell, 293T Cells, 293T HEK 293 Cells 293 Cell, HEK 293 Cells, HEK Cell, HEK 293 Cells, HEK 293 HEK 293 Cell Human Kidney Cell Line 293 Human Embryonic Kidney Cell Line 293 HEK 293 Cell Line

Below are MeSH descriptors whose meaning is more general than "HEK293 Cells".

Anatomy [A]
Cells [A11]
Cells, Cultured [A11.251]
Cell Line [A11.251.210]
Cell Line, Transformed [A11.251.210.172]
HEK293 Cells [A11.251.210.172.750]
Epithelial Cells [A11.436]
HEK293 Cells [A11.436.334]

Below are MeSH descriptors whose meaning is more specific than "HEK293 Cells".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "HEK293 Cells" by people in this website by year, and whether "HEK293 Cells" was a major or minor topic of these publications.

Bar chart showing 320 publications over 16 distinct years, with a maximum of 35 publications in 2014

To see the data from this visualization as text, click here.

Year	Minor Topic	Total
2010	12	12
2011	29	29
2012	20	20
2013	31	31
2014	35	35
2015	33	33
2016	22	22
2017	23	23
2018	25	25
2019	21	21
2020	27	27
2021	21	21
2022	3	3
2023	5	5
2024	10	10
2025	3	3

Below are the most recent publications written about "HEK293 Cells" by people in Profiles.

Chahdi A, Jorgez C, Rosenfeld JA, Neetu N, Seth A. Androgen receptor ubiquitination links KCTD13 to genitourinary tract defects. FASEB J. 2025 Feb 28; 39(4):e70406.

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Hanselman EC, Harmon CP, Deng D, Sywanycz SM, Caronia L, Jiang P, Breslin PAS. Ibuprofen inhibits human sweet taste and glucose detection implicating an additional mechanism of metabolic disease risk reduction. Br J Pharmacol. 2025 Jun; 182(12):2682-2693.

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Kim KM, Girdhar A, Cicardi ME, Kankate V, Hayashi M, Yang R, Carey JL, Fare CM, Shorter J, Cingolani G, Trotti D, Guo L. NLS-binding deficient Kap?2 reduces neurotoxicity via selective interaction with C9orf72-ALS/FTD dipeptide repeats. Commun Biol. 2025 Jan 02; 8(1):2.

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Valerie NCK, Sanjiv K, Mortusewicz O, Zhang SM, Alam S, Pires MJ, Stigsdotter H, Rasti A, Langelier MF, Rehling D, Throup A, Purewal-Sidhu O, Desroses M, Onireti J, Wakchaure P, Alml?f I, Bostr?m J, Bevc L, Benzi G, Stenmark P, Pascal JM, Helleday T, Page BDG, Altun M. Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM. Nat Commun. 2024 12 06; 15(1):10347.

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Sharma AL, Tyagi P, Khumallambam M, Tyagi M. Cocaine-Induced DNA-Dependent Protein Kinase Relieves RNAP II Pausing by Promoting TRIM28 Phosphorylation and RNAP II Hyperphosphorylation to Enhance HIV Transcription. Cells. 2024 11 23; 13(23).

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Langelier MF, Mirhasan M, Gilbert K, Sverzhinksy A, Furtos A, Pascal JM. PARP enzyme de novo synthesis of protein-free poly(ADP-ribose). Mol Cell. 2024 Dec 19; 84(24):4758-4773.e6.

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Maharjan S, Gamper H, Yamaki Y, Christian T, Henley RY, Li NS, Suzuki T, Suzuki T, Piccirilli JA, Wanunu M, Seifert E, Wallace DC, Hou YM. Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology. Nat Commun. 2024 10 18; 15(1):9008.

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De Pascali F, Inoue A, Benovic JL. Diverse pathways in GPCR-mediated activation of Ca2+ mobilization in HEK293 cells. J Biol Chem. 2024 11; 300(11):107882.

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Hayashi M, Girdhar A, Ko YH, Kim KM, DePierro JA, Buchler JR, Arunprakash N, Bajaj A, Cingolani G, Guo L. Engineered NLS-chimera downregulates expression of aggregation-prone endogenous FUS. Nat Commun. 2024 09 10; 15(1):7887.

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Vukovic I, Barnada SM, Ruffin JW, Karlin J, Lokareddy RK, Cingolani G, McMahon SB. Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b. Life Sci Alliance. 2024 11; 7(11).

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