Hydrophobic and Hydrophilic Interactions

"Hydrophobic and Hydrophilic Interactions" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The thermodynamic interaction between a substance and WATER.

Descriptor ID	D057927
MeSH Number(s)	G02.409
Concept/Terms	Hydrophobic and Hydrophilic Interactions Hydrophobic and Hydrophilic Interactions Hydrophilic and Hydrophobic Interactions Hydrophobicity Hydrophobicity Hydrophobicities Hydrophobic Interactions Hydrophobic Interactions Hydrophobic Interaction Interaction, Hydrophobic Interactions, Hydrophobic Hydrophilic Interactions Hydrophilic Interactions Hydrophilic Interaction Interaction, Hydrophilic Interactions, Hydrophilic Hydrophilicity Hydrophilicity Hydrophilicities

Below are MeSH descriptors whose meaning is more general than "Hydrophobic and Hydrophilic Interactions".

Biological Sciences [G]
Chemical Phenomena [G02]
Hydrophobic and Hydrophilic Interactions [G02.409]

Below are MeSH descriptors whose meaning is more specific than "Hydrophobic and Hydrophilic Interactions".

Hydrophobic and Hydrophilic Interactions
Wettability

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Hydrophobic and Hydrophilic Interactions" by people in this website by year, and whether "Hydrophobic and Hydrophilic Interactions" was a major or minor topic of these publications.

Bar chart showing 35 publications over 19 distinct years, with a maximum of 5 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	2	2
2003	0	1	1
2004	0	2	2
2005	0	3	3
2006	0	2	2
2007	0	2	2
2008	0	2	2
2009	0	1	1
2010	0	3	3
2011	1	4	5
2012	1	1	2
2014	2	0	2
2015	0	1	1
2016	0	1	1
2018	0	1	1
2019	0	2	2
2022	0	1	1
2024	0	1	1
2025	0	1	1

Below are the most recent publications written about "Hydrophobic and Hydrophilic Interactions" by people in Profiles.

Yang DB, Zhang T, Blum JE, Kloxin CJ, Pochan DJ, Saven JG. Complementary Peptide Interactions Support the Ultra-Rigidity of Polymers of De Novo Designed Click-Functionalized Bundlemers. J Phys Chem B. 2025 02 06; 129(5):1462-1474.

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Lee J, Tang Y, Cure?o Hernandez KE, Kim S, Lee R, Cartwright Z, Pochan DJ, Herrera-Alonso M. Ultrastable and Redispersible Zwitterionic Bottlebrush Micelles for Drug Delivery. ACS Appl Mater Interfaces. 2024 10 16; 16(41):55118-55129.

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Guo R, Sinha NJ, Misra R, Tang Y, Langenstein M, Kim K, Fagan JA, Kloxin CJ, Jensen G, Pochan DJ, Saven JG. Computational Design of Homotetrameric Peptide Bundle Variants Spanning a Wide Range of Charge States. Biomacromolecules. 2022 04 11; 23(4):1652-1661.

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Gelenter MD, Smith KJ, Liao SY, Mandala VS, Dregni AJ, Lamm MS, Tian Y, Xu W, Pochan DJ, Tucker TJ, Su Y, Hong M. The peptide hormone glucagon forms amyloid fibrils with two coexisting ?-strand conformations. Nat Struct Mol Biol. 2019 07; 26(7):592-598.

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R?ter A, Kuczera S, Pochan DJ, Olsson U. Twisted Ribbon Aggregates in a Model Peptide System. Langmuir. 2019 04 30; 35(17):5802-5808.

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Haider MJ, Zhang HV, Sinha N, Fagan JA, Kiick KL, Saven JG, Pochan DJ. Self-assembly and soluble aggregate behavior of computationally designed coiled-coil peptide bundles. Soft Matter. 2018 Jul 04; 14(26):5488-5496.

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Sun JE, Stewart B, Litan A, Lee SJ, Schneider JP, Langhans SA, Pochan DJ. Sustained release of active chemotherapeutics from injectable-solid ?-hairpin peptide hydrogel. Biomater Sci. 2016 May 26; 4(5):839-48.

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Albala L, Ercan UK, Joshi SG, Eisenbrey JR, Teraphongphom N, Wheatley MA. Preservation of imaging capability in sensitive ultrasound contrast agents after indirect plasma sterilization. Int J Pharm. 2015 Oct 15; 494(1):146-51.

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Sathaye S, Zhang H, Sonmez C, Schneider JP, MacDermaid CM, Von Bargen CD, Saven JG, Pochan DJ. Engineering complementary hydrophobic interactions to control ?-hairpin peptide self-assembly, network branching, and hydrogel properties. Biomacromolecules. 2014 Nov 10; 15(11):3891-900.

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Juurinen I, Pylkk?nen T, Sahle CJ, Simonelli L, H?m?l?inen K, Huotari S, Hakala M. Effect of the hydrophobic alcohol chain length on the hydrogen-bond network of water. J Phys Chem B. 2014 Jul 24; 118(29):8750-5.

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