Receptors, Prostaglandin E, EP2 Subtype
"Receptors, Prostaglandin E, EP2 Subtype" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subtype of prostaglandin E receptors that specifically couples to GS ALPHA GTP-BINDING PROTEIN SUBUNITS and subsequently activates ADENYLYL CYCLASES.
| Descriptor ID |
D058307
|
| MeSH Number(s) |
D12.776.543.750.695.200.700.600.200
|
| Concept/Terms |
Receptors, Prostaglandin E, EP2 Subtype- Receptors, Prostaglandin E, EP2 Subtype
- Prostaglandin E Receptor 2
- Prostanoid Receptor EP2
- EP2, Prostanoid Receptor
- Receptor EP2, Prostanoid
- PGE Receptor, EP2 Subtype
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Prostaglandin E, EP2 Subtype".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Prostaglandin E, EP2 Subtype".
This graph shows the total number of publications written about "Receptors, Prostaglandin E, EP2 Subtype" by people in this website by year, and whether "Receptors, Prostaglandin E, EP2 Subtype" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 0 | 2 | 2 |
| 2005 | 0 | 1 | 1 |
| 2019 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
| 2025 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptors, Prostaglandin E, EP2 Subtype" by people in Profiles.
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Javed E, Nayak AP, Jannu AK, Cohen AH, Dewes I, Wang R, Tang DD, Deshpande DA, Penn RB. A-Kinase-Anchoring Protein Subtypes Differentially Regulate GPCR Signaling and Function in Human Airway Smooth Muscle. Am J Respir Cell Mol Biol. 2025 02; 72(2):133-144.
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De Pascali F, Inoue A, Benovic JL. Diverse pathways in GPCR-mediated activation of Ca2+ mobilization in HEK293 cells. J Biol Chem. 2024 11; 300(11):107882.
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Nayak AP, Javed E, Villalba DR, Wang Y, Morelli HP, Shah SD, Kim N, Ostrom RS, Panettieri RA, An SS, Tang DD, Penn RB. Prorelaxant E-type Prostanoid Receptors Functionally Partition to Different Procontractile Receptors in Airway Smooth Muscle. Am J Respir Cell Mol Biol. 2023 11; 69(5):584-591.
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Nunez FJ, Schulte NA, Fogel DM, Michalski J, Rennard SI, Penn RB, Toews ML, Ostrom RS. Agonist-specific desensitization of PGE2-stimulated cAMP signaling due to upregulated phosphodiesterase expression in human lung fibroblasts. Naunyn Schmiedebergs Arch Pharmacol. 2020 05; 393(5):843-856.
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Michael JV, Gavrila A, Nayak AP, Pera T, Liberato JR, Polischak SR, Shah SD, Deshpande DA, Penn RB. Cooperativity of E-prostanoid receptor subtypes in regulating signaling and growth inhibition in human airway smooth muscle. FASEB J. 2019 04; 33(4):4780-4789.
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Guo M, Pascual RM, Wang S, Fontana MF, Valancius CA, Panettieri RA, Tilley SL, Penn RB. Cytokines regulate beta-2-adrenergic receptor responsiveness in airway smooth muscle via multiple PKA- and EP2 receptor-dependent mechanisms. Biochemistry. 2005 Oct 25; 44(42):13771-82.
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Genetos DC, Geist DJ, Liu D, Donahue HJ, Duncan RL. Fluid shear-induced ATP secretion mediates prostaglandin release in MC3T3-E1 osteoblasts. J Bone Miner Res. 2005 Jan; 20(1):41-9.
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Han S, Roman J. Suppression of prostaglandin E2 receptor subtype EP2 by PPARgamma ligands inhibits human lung carcinoma cell growth. Biochem Biophys Res Commun. 2004 Feb 20; 314(4):1093-9.
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Penn RB, Pascual RM, Kim YM, Mundell SJ, Krymskaya VP, Panettieri RA, Benovic JL. Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. J Biol Chem. 2001 Aug 31; 276(35):32648-56.