"Myofibroblasts" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Spindle-shaped cells with characteristic CONTRACTILE PROTEINS and structures that contribute to the WOUND HEALING process. They occur in GRANULATION TISSUE and also in pathological processes such as FIBROSIS.
| Descriptor ID |
D058628
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| MeSH Number(s) |
A11.329.228.975 A11.620.520.500
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Myofibroblasts".
Below are MeSH descriptors whose meaning is more specific than "Myofibroblasts".
This graph shows the total number of publications written about "Myofibroblasts" by people in this website by year, and whether "Myofibroblasts" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2010 | 1 | 0 | 1 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 1 | 1 | 2 |
| 2016 | 0 | 2 | 2 |
| 2017 | 0 | 3 | 3 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 1 | 1 | 2 |
| 2021 | 1 | 3 | 4 |
| 2022 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Myofibroblasts" by people in Profiles.
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Jimenez SA, Piera-Velazquez S. Cellular Transdifferentiation: A Crucial Mechanism of Fibrosis in Systemic Sclerosis. Curr Rheumatol Rev. 2024; 20(4):388-404.
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Song J, Gao H, Zhang H, George OJ, Hillman AS, Fox JM, Jia X. Matrix Adhesiveness Regulates Myofibroblast Differentiation from Vocal Fold Fibroblasts in a Bio-orthogonally Cross-linked Hydrogel. ACS Appl Mater Interfaces. 2022 Nov 23; 14(46):51669-51682.
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Basta MD, Paulson H, Walker JL. The local wound environment is a key determinant of the outcome of TGF? signaling on the fibrotic response of CD44+ leader cells in an ex vivo post-cataract-surgery model. Exp Eye Res. 2021 12; 213:108829.
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Abignano G, Hermes H, Piera-Velazquez S, Addya S, Del Galdo F, Jimenez SA. Global gene expression analysis of systemic sclerosis myofibroblasts demonstrates a marked increase in the expression of multiple NBPF genes. Sci Rep. 2021 10 14; 11(1):20435.
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D'Agostino I, Tacconelli S, Bruno A, Contursi A, Mucci L, Hu X, Xie Y, Chakraborty R, Jain K, Sacco A, Zucchelli M, Landolfi R, Dovizio M, Falcone L, Ballerini P, Hwa J, Patrignani P. Low-dose Aspirin prevents hypertension and cardiac fibrosis when thromboxane A2 is unrestrained. Pharmacol Res. 2021 08; 170:105744.
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Menko AS, DeDreu J, Logan CM, Paulson H, Levin AV, Walker JL. Resident immune cells of the avascular lens: Mediators of the injury and fibrotic response of the lens. FASEB J. 2021 04; 35(4):e21341.
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Macarak EJ, Wermuth PJ, Rosenbloom J, Uitto J. Keloid disorder: Fibroblast differentiation and gene expression profile in fibrotic skin diseases. Exp Dermatol. 2021 01; 30(1):132-145.
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Wasson CW, Abignano G, Hermes H, Malaab M, Ross RL, Jimenez SA, Chang HY, Feghali-Bostwick CA, Del Galdo F. Long non-coding RNA HOTAIR drives EZH2-dependent myofibroblast activation in systemic sclerosis through miRNA 34a-dependent activation of NOTCH. Ann Rheum Dis. 2020 04; 79(4):507-517.
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Schnieder J, Mamazhakypov A, Birnhuber A, Wilhelm J, Kwapiszewska G, Ruppert C, Markart P, Wujak L, Rubio K, Barreto G, Schaefer L, Wygrecka M. Loss of LRP1 promotes acquisition of contractile-myofibroblast phenotype and release of active TGF-?1 from ECM stores. Matrix Biol. 2020 06; 88:69-88.
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Piera-Velazquez S, Jimenez SA. Simultaneous inhibition of c-Abl and Src kinases abrogates the exaggerated expression of profibrotic genes in cultured systemic sclerosis dermal fibroblasts. Clin Exp Rheumatol. 2018 Jul-Aug; 36 Suppl 113(4):36-44.