High-Throughput Nucleotide Sequencing

"High-Throughput Nucleotide Sequencing" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Techniques of nucleotide sequence analysis that increase the range, complexity, sensitivity, and accuracy of results by greatly increasing the scale of operations and thus the number of nucleotides, and the number of copies of each nucleotide sequenced. The sequencing may be done by analysis of the synthesis or ligation products, hybridization to preexisting sequences, etc.

Descriptor ID	D059014
MeSH Number(s)	E05.393.760.319
Concept/Terms	High-Throughput Nucleotide Sequencing High-Throughput Nucleotide Sequencing High Throughput Nucleotide Sequencing Nucleotide Sequencing, High-Throughput Sequencing, High-Throughput Nucleotide Massively-Parallel Sequencing Massively-Parallel Sequencing Massively Parallel Sequencing Sequencing, Massively-Parallel Sequencings, Massively-Parallel High-Throughput RNA Sequencing High-Throughput RNA Sequencing High Throughput RNA Sequencing RNA Sequencing, High-Throughput Sequencing, High-Throughput RNA Deep Sequencing Deep Sequencing Deep Sequencings Sequencing, Deep Sequencings, Deep High-Throughput DNA Sequencing High-Throughput DNA Sequencing DNA Sequencing, High-Throughput High Throughput DNA Sequencing High-Throughput DNA Sequencings Sequencing, High-Throughput DNA

Below are MeSH descriptors whose meaning is more general than "High-Throughput Nucleotide Sequencing".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Genetic Techniques [E05.393]
Sequence Analysis [E05.393.760]
High-Throughput Nucleotide Sequencing [E05.393.760.319]

Below are MeSH descriptors whose meaning is related to "High-Throughput Nucleotide Sequencing".

Below are MeSH descriptors whose meaning is more specific than "High-Throughput Nucleotide Sequencing".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "High-Throughput Nucleotide Sequencing" by people in this website by year, and whether "High-Throughput Nucleotide Sequencing" was a major or minor topic of these publications.

Bar chart showing 149 publications over 13 distinct years, with a maximum of 24 publications in 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2013	2	5	7
2014	8	5	13
2015	5	8	13
2016	4	13	17
2017	4	11	15
2018	9	7	16
2019	2	16	18
2020	9	15	24
2021	4	8	12
2022	0	5	5
2023	2	2	4
2024	1	3	4
2025	0	1	1

Below are the most recent publications written about "High-Throughput Nucleotide Sequencing" by people in Profiles.

Lasota J, Kaczorowski M, Chlopek M, Milek-Krupa J, Szczepaniak M, Ylaya K, Chodyna M, Izycka-Swieszewska E, Scherping A, Czapiewski P, Dziuba I, Kato Y, Halon A, Kowalik A, Miettinen M. An immunohistochemical and molecular genetic study of 60 colorectal carcinoma brain metastases in pursuit of predictive biomarkers for cancer therapy. Hum Pathol. 2025 Jan; 155:105717.

View in: PubMed
Gilstrop Thompson M, Xu W, Moore B, Wang T, Sun N, Pewar H, Avent ND, Vernaza A, Acosta F, Saben JL, Souter V, Parmar S, Sengupta U, Altug Y, EmBree J, Cantos C, Kotwaliwale C, Babiarz J, Zimmermann B, Swenerton R, Meltzer JT. Clinical Validation of a Prenatal Cell-Free DNA Screening Test for Fetal RHD in a Large U.S. Cohort. Obstet Gynecol. 2025 02 01; 145(2):211-216.

View in: PubMed
Volovsky M, Scott RT, Seli E. Non-invasive preimplantation genetic testing for aneuploidy: is the promise real? Hum Reprod. 2024 09 01; 39(9):1899-1908.

View in: PubMed
Piera-Velazquez S, Fortina P, Jimenez SA. Comparison of serum exosome miRNA from patients with Raynaud's phenomenon with positive and negative serum antinuclear antibodies. Clin Exp Rheumatol. 2024 Aug; 42(8):1629-1634.

View in: PubMed
Shah D, Wells A, Cox M, Dawravoo K, Abad J, D'Souza A, Suh G, Bayer R, Chaudhry S, Zhang Q, Cristofanilli M, Bentrem D, Chawla A. Prospective Evaluation of Circulating Tumor DNA Using Next-generation Sequencing as a Biomarker During Neoadjuvant Chemotherapy in Localized Pancreatic Cancer. Ann Surg. 2025 06 01; 281(6):997-1005.

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Wang F, Xu Y, Wang R, Zhang B, Smith N, Notaro A, Gaerlan S, Kutschera E, Kadash-Edmondson KE, Xing Y, Lin L. TEQUILA-seq: a versatile and low-cost method for targeted long-read RNA sequencing. Nat Commun. 2023 08 08; 14(1):4760.

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Fern?ndez-Rodr?guez D, Cho J, Parvizi N, Khan AZ, Parvizi J, Namdari S. Next-generation Sequencing Results Require Higher Inoculum for Cutibacterium acnes Detection Than Conventional Anaerobic Culture. Clin Orthop Relat Res. 2023 12 01; 481(12):2484-2491.

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Riman S, Ghemrawi M, Borsuk LA, Mahfouz R, Walsh S, Vallone PM. Sequence-based allelic variations and frequencies for 22 autosomal STR loci in the Lebanese population. Forensic Sci Int Genet. 2023 07; 65:102872.

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Kullar R, Chisari E, Snyder J, Cooper C, Parvizi J, Sniffen J. Next-Generation Sequencing Supports Targeted Antibiotic Treatment for Culture Negative Orthopedic Infections. Clin Infect Dis. 2023 01 13; 76(2):359-364.

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Ghemrawi M, Tejero NF, Duncan G, McCord B. Pyrosequencing: Current forensic methodology and future applications-a review. Electrophoresis. 2023 01; 44(1-2):298-312.

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