Caspase Inhibitors

"Caspase Inhibitors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Endogenous and exogenous compounds and that either inhibit CASPASES or prevent their activation.

Descriptor ID	D061945
MeSH Number(s)	D27.505.519.389.745.325.500
Concept/Terms	Caspase Inhibitors Caspase Inhibitors Inhibitors, Caspase Caspase Blockers Blockers, Caspase Caspase Activation Inhibitors Caspase Activation Inhibitors Activation Inhibitors, Caspase Inhibitors, Caspase Activation Caspase Activation Blockers Activation Blockers, Caspase Blockers, Caspase Activation Capase Activation Inhibitors Activation Inhibitors, Capase Inhibitors, Capase Activation

Below are MeSH descriptors whose meaning is more general than "Caspase Inhibitors".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Molecular Mechanisms of Pharmacological Action [D27.505.519]
Enzyme Inhibitors [D27.505.519.389]
Protease Inhibitors [D27.505.519.389.745]
Cysteine Proteinase Inhibitors [D27.505.519.389.745.325]
Caspase Inhibitors [D27.505.519.389.745.325.500]

Below are MeSH descriptors whose meaning is related to "Caspase Inhibitors".

Below are MeSH descriptors whose meaning is more specific than "Caspase Inhibitors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Caspase Inhibitors" by people in this website by year, and whether "Caspase Inhibitors" was a major or minor topic of these publications.

Bar chart showing 12 publications over 8 distinct years, with a maximum of 2 publications in 2004 and 2006 and 2012 and 2015

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2002	0	1	1
2004	0	2	2
2006	0	2	2
2009	0	1	1
2012	1	1	2
2015	1	1	2
2016	0	1	1

Below are the most recent publications written about "Caspase Inhibitors" by people in Profiles.

Nastase MV, Zeng-Brouwers J, Frey H, Hsieh LT, Poluzzi C, Beckmann J, Schroeder N, Pfeilschifter J, Lopez-Mosqueda J, Mersmann J, Ikeda F, Iozzo RV, Dikic I, Schaefer L. An Essential Role for SHARPIN in the Regulation of Caspase 1 Activity in Sepsis. Am J Pathol. 2016 05; 186(5):1206-20.

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Stammler D, Eigenbrod T, Menz S, Frick JS, Sweet MJ, Shakespear MR, Jantsch J, Siegert I, W?lfle S, Langer JD, Oehme I, Schaefer L, Fischer A, Knievel J, Heeg K, Dalpke AH, Bode KA. Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1? via a Caspase-1-Independent Mechanism. J Immunol. 2015 Dec 01; 195(11):5421-31.

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Terlizzi M, Di Crescenzo VG, Perillo G, Galderisi A, Pinto A, Sorrentino R. Pharmacological inhibition of caspase-8 limits lung tumour outgrowth. Br J Pharmacol. 2015 Aug; 172(15):3917-28.

View in: PubMed
Ghavami S, Yeganeh B, Stelmack GL, Kashani HH, Sharma P, Cunnington R, Rattan S, Bathe K, Klonisch T, Dixon IM, Freed DH, Halayko AJ. Apoptosis, autophagy and ER stress in mevalonate cascade inhibition-induced cell death of human atrial fibroblasts. Cell Death Dis. 2012 Jun 21; 3:e330.

View in: PubMed
Louboutin JP, Agrawal L, Reyes BA, van Bockstaele EJ, Strayer DS. Gene delivery of antioxidant enzymes inhibits human immunodeficiency virus type 1 gp120-induced expression of caspases. Neuroscience. 2012 Jul 12; 214:68-77.

View in: PubMed
Showalter SL, Wang Z, Costantino CL, Witkiewicz AK, Yeo CJ, Brody JR, Carr BI. Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway. J Gastroenterol Hepatol. 2010 Apr; 25(4):738-44.

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Tafani M, Karpinich NO, Serroni A, Russo MA, Farber JL. Re-evaluation of the distinction between type I and type II cells: the necessary role of the mitochondria in both the extrinsic and intrinsic signaling pathways upon Fas receptor activation. J Cell Physiol. 2006 Sep; 208(3):556-65.

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Karpinich NO, Tafani M, Schneider T, Russo MA, Farber JL. The course of etoposide-induced apoptosis in Jurkat cells lacking p53 and Bax. J Cell Physiol. 2006 Jul; 208(1):55-63.

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Liu HR, Gao E, Hu A, Tao L, Qu Y, Most P, Koch WJ, Christopher TA, Lopez BL, Alnemri ES, Zervos AS, Ma XL. Role of Omi/HtrA2 in apoptotic cell death after myocardial ischemia and reperfusion. Circulation. 2005 Jan 04; 111(1):90-6.

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Liu HR, Gao F, Tao L, Yan WL, Gao E, Christopher TA, Lopez BL, Hu A, Ma XL. Antiapoptotic mechanisms of benidipine in the ischemic/reperfused heart. Br J Pharmacol. 2004 Jun; 142(4):627-34.

View in: PubMed

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