"Claudin-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An integral membrane protein that is localized to TIGHT JUNCTIONS, where it plays a role in controlling the paracellular permeability of polarized cells. Mutations in the gene for claudin-1 are associated with Neonatal Ichthyosis-Sclerosing Cholangitis (NISCH) Syndrome.
| Descriptor ID |
D062445
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| MeSH Number(s) |
D12.776.543.940.200.100
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Claudin-1".
Below are MeSH descriptors whose meaning is more specific than "Claudin-1".
This graph shows the total number of publications written about "Claudin-1" by people in this website by year, and whether "Claudin-1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2020 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Claudin-1" by people in Profiles.
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Salik D, Hadj-Rabia S, Hohl D, Vahidnezhad H, Youssefian L, Rakosi A, Dangoisse C, Marangoni M, Vilain C, Smits G. Evaluation of neurodevelopmental symptoms in 10 cases of neonatal ichthyosis and sclerosing cholangitis syndrome. Pediatr Dermatol. 2022 Jul; 39(4):590-593.
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Uitto J, Youssefian L, Saeidian AH, Vahidnezhad H. Molecular Genetics of Keratinization Disorders - What's New About Ichthyosis. Acta Derm Venereol. 2020 Mar 25; 100(7):adv00095.
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Youssefian L, Vahidnezhad H, Saeidian AH, Sotoudeh S, Zeinali S, Uitto J. Gene-Targeted Next-Generation Sequencing Identifies a Novel CLDN1 Mutation in a Consanguineous Family With NISCH Syndrome. Am J Gastroenterol. 2017 Feb; 112(2):396-398.
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Lai-Cheong JE, Arita K, McGrath JA. Genetic diseases of junctions. J Invest Dermatol. 2007 Dec; 127(12):2713-25.
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Mullin JM, Valenzano MC, Trembeth S, Allegretti PD, Verrecchio JJ, Schmidt JD, Jain V, Meddings JB, Mercogliano G, Thornton JJ. Transepithelial leak in Barrett's esophagus. Dig Dis Sci. 2006 Dec; 51(12):2326-36.
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Rendon-Huerta E, Valenzano MC, Mullin JM, Trembeth SE, Kothari R, Hameed B, Mercogliano G, Thornton JJ. Comparison of three integral tight junction barrier proteins in Barrett's epithelium versus normal esophageal epithelium. Am J Gastroenterol. 2003 Aug; 98(8):1901-3.