Thomas Jefferson University

Shengwen Li

TitleVolunteer Faculty
InstitutionThomas Jefferson University
DepartmentFaculty Records and Publicatio - Thomas Jefferson University
Address833 Chestnut Street
Philadelphia PA 19023
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xu Y, Li SC, Xiao J, Liu Q, Cherukuri D, Liu Y, Mirshahidi S, Xu J, Chen X, Homa D, Olea J, Wu K, Kelly KR, Sun F, Huang R, Wang X, Wen Q, Zhang X, Ghiuzeli CM, Chong E, Abdel-Azim H, Reeves ME, Baylink DJ, Cao H, Zhong JF. Exploring treatment-driven subclonal evolution of prognostic triple biomarkers: Dual gene fusions and chimeric RNA variants in novel subtypes of acute myeloid leukemia patients with KMT2A rearrangement. Drug Resist Updat. 2025 Mar; 79:101199. PMID: 39823827.
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    2. Stucky A, Viet CT, Aouizerat BE, Ye Y, Doan C, Mundluru T, Sedhiazadeh P, Sinha UK, Chen X, Zhang X, Li SC, Cai J, Zhong JF. Single-Cell Molecular Profiling of Head and Neck Squamous Cell Carcinoma Reveals Five Dysregulated Signaling Pathways Associated With Circulating Tumor Cells. Cancer Control. 2024 Jan-Dec; 31:10732748241251571. PMID: 38869038.
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    3. Li SC. Mastering the craft: Creating an insightful and widely-cited literature review. World J Stem Cells. 2023 Aug 26; 15(8):781-786. PMID: 37700820.
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    4. Chai C, Sui K, Tang J, Yu H, Yang C, Zhang H, Li SC, Zhong JF, Wang Z, Zhang X. BCR-ABL1-driven exosome-miR130b-3p-mediated gap-junction Cx43 MSC intercellular communications imply therapies of leukemic subclonal evolution. Theranostics. 2023; 13(12):3943-3963. PMID: 37554265.
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    5. Wang J, Li X, Zhou J, Qiu D, Zhang M, Sun L, Li SC. Long-term survival with anlotinib as a front-line treatment in an elderly NSCLC patient: A case report. Front Oncol. 2023; 13:1043244. PMID: 37091182.
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    6. Zhang J, Su Q, Li SC. Qigong Exercise Balances Oxygen Supply and Acid-Base to Modulate Hypoxia: A Perspective Platform toward Preemptive Health & Medicine. Med Sci (Basel). 2023 02 28; 11(1). PMID: 36976529.
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    7. Sun L, Li X, Tu L, Stucky A, Huang C, Chen X, Cai J, Li SC. RNA-Sequencing Combined With Genome-Wide Allele-Specific Expression Patterning Identifies ZNF44 Variants as a Potential New Driver Gene for Pediatric Neuroblastoma. Cancer Control. 2023 Jan-Dec; 30:10732748231175017. PMID: 37161925.
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    8. Li SC, Kabeer MH. Caveolae-Mediated Extracellular Vesicle (CMEV) Signaling of Polyvalent Polysaccharide Vaccination: A Host-Pathogen Interface Hypothesis. Pharmaceutics. 2022 Nov 30; 14(12). PMID: 36559147.
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    9. Li SC, He JG. A generalizable and tunable engineered ecosystem provides a clear route to prosperity and well-being to harness the world's aquatic "blue" food systems to help end hunger: A perspective. Front Food Sci Technol. 2022; 2. PMID: 36312446.
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    10. Li X, Wang X, Huang R, Stucky A, Chen X, Sun L, Wen Q, Zeng Y, Fletcher H, Wang C, Xu Y, Cao H, Sun F, Li SC, Zhang X, Zhong JF. The Machine-Learning-Mediated Interface of Microbiome and Genetic Risk Stratification in Neuroblastoma Reveals Molecular Pathways Related to Patient Survival. Cancers (Basel). 2022 Jun 10; 14(12). PMID: 35740540.
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    11. Stucky A, Gao L, Li SC, Tu L, Luo J, Huang X, Chen X, Li X, Park TH, Cai J, Kabeer MH, Plant AS, Sun L, Zhang X, Zhong JF. Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes. Front Cell Dev Biol. 2022; 10:699144. PMID: 35356283.
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    12. Li X, Sun L, Stucky A, Tu L, Cai J, Chen X, Wu Z, Jiang X, Li SC. Reply to Schramm, L. Comment on "Li et al. BDP1 Variants I1264M and V1347M Significantly Associated with Clinical Outcomes of Pediatric Neuroblastoma Patients Imply a New Prognostic Biomarker: A 121-Patient Cancer Genome Study. Diagnostics 2021, 11, 2364". Diagnostics (Basel). 2022 Mar 02; 12(3). PMID: 35328170.
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    13. Zhang X, Hou L, Li F, Zhang W, Wu C, Xiang L, Li J, Zhou L, Wang X, Xiang Y, Xiao Y, Li SC, Chen L, Ran Q, Li Z. Piezo1-mediated mechanosensation in bone marrow macrophages promotes vascular niche regeneration after irradiation injury. Theranostics. 2022; 12(4):1621-1638. PMID: 35198061.
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    14. Li X, Sun L, Stucky A, Tu L, Cai J, Chen X, Wu Z, Jiang X, Li SC. BDP1 Variants I1264M and V1347M Significantly Associated with Clinical Outcomes of Pediatric Neuroblastoma Patients Imply a New Prognostic Biomarker: A 121-Patient Cancer Genome Study. Diagnostics (Basel). 2021 Dec 15; 11(12). PMID: 34943600.
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    15. Wang M, Chen Y, Zhao Z, Weng S, Yang J, Liu S, Liu C, Yuan F, Ai B, Zhang H, Zhang M, Lu L, Yuan K, Yu Z, Mo B, Liu X, Gai C, Li Y, Lu R, Zhong Z, Zheng L, Feng G, Li SC, He J. A convenient polyculture system that controls a shrimp viral disease with a high transmission rate. Commun Biol. 2021 11 11; 4(1):1276. PMID: 34764419.
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    16. Sun M, Xue X, Li L, Xu D, Li S, Li SC, Su Q. Ectosome biogenesis and release processes observed by using live-cell dynamic imaging in mammalian glial cells. Quant Imaging Med Surg. 2021 Nov; 11(11):4604-4616. PMID: 34737927.
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    17. Li F, Zhang R, Hu C, Ran Q, Xiang Y, Xiang L, Chen L, Yang Y, Li SC, Zhang G, Li Z. Irradiation Haematopoiesis Recovery Orchestrated by IL-12/IL-12R?1/TYK2/STAT3-Initiated Osteogenic Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells. Front Cell Dev Biol. 2021; 9:729293. PMID: 34540843.
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    18. Zhang XM, Chen DG, Li SC, Zhu B, Li ZJ. Embryonic Origin and Subclonal Evolution of Tumor-Associated Macrophages Imply Preventive Care for Cancer. Cells. 2021 04 14; 10(4). PMID: 33919979.
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    19. Stucky A, Gao L, Sun L, Li SC, Chen X, Park TH, Cai J, Kabeer MH, Zhang X, Sinha UK, Zhong JF. Evidence for AJUBA-catenin-CDH4-linked differentiation resistance of mesenchymal stem cells implies tumorigenesis and progression of head and neck squamous cell carcinoma: a single-cell transcriptome approach. Blood Genom. 2021; 5(1):29-39. PMID: 34368804.
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    20. Lee LX, Li SC. Hunting down the dominating subclone of cancer stem cells as a potential new therapeutic target in multiple myeloma: An artificial intelligence perspective. World J Stem Cells. 2020 Aug 26; 12(8):706-720. PMID: 32952853.
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    21. Li SC, Kabeer MH. Autologous Splenocyte Reinfusion Improves Antibody-Mediated Immune Response to the 23-Valent Pneumococcal Polysaccharide-Based Vaccine in Splenectomized Mice. Biomolecules. 2020 05 01; 10(5). PMID: 32369978.
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    22. Xiang LX, Ran Q, Chen L, Xiang Y, Li FJ, Zhang XM, Xiao YN, Zou LY, Zhong JF, Li SC, Li ZJ. CR6-interacting factor-1 contributes to osteoclastogenesis by inducing receptor activator of nuclear factor ?B ligand after radiation. World J Stem Cells. 2020 Mar 26; 12(3):222-240. PMID: 32266053.
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    23. Li SC, Sparks KJ, Sender LS. Implementation and Validation of the Roche Light Cycler 480 96-Well Plate Platform as a Real-Time PCR Assay for the Quantitative Detection of Cytomegalovirus (CMV) in Clinical Specimens Using the Luminex MultiCode ASRs System. Med Sci (Basel). 2020 Mar 11; 8(1). PMID: 32168800.
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    24. Wang X, Zhou Y, Liu L, Ma J, Wu H, Zhao L, Chen W, Li SC, Ran Q, Li Z. Coronavirus disease 2019 (COVID-19): diagnosis and prognosis. Blood Genom. 2020; 4(2):96-107. PMID: 33768219.
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    25. Zhang J, Su Q, Loudon WG, Lee KL, Luo J, Dethlefs BA, Li SC. Breathing Signature as Vitality Score Index Created by Exercises of Qigong: Implications of Artificial Intelligence Tools Used in Traditional Chinese Medicine. J Funct Morphol Kinesiol. 2019 Dec; 4(4). PMID: 31853512.
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    26. Ran Q, Jin F, Xiang Y, Xiang L, Wang Q, Li F, Chen L, Zhang Y, Wu C, Zhou L, Xiao Y, Chen L, Wu J, Zhong JF, Li SC, Li Z. CRIF1 as a potential target to improve the radiosensitivity of osteosarcoma. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20511-20516. PMID: 31548420.
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    27. Li SC, Rangel AD, Kabeer MH. Precision Technique for Splenectomy Limits Mouse Stress Responses for Accurate and Realistic Measurements for Investigating Inflammation and Immunity. Bio Protoc. 2019 Aug 05; 9(15). PMID: 31497622.
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    28. Li SC, Luo J, Lee KL. Cancer Niche as a Garbage Disposal Machine: Implications of TCM-Mediated Balance of Body-Disease for Treatment of Cancer. Online J Complement Altern Med. 2019; 1(3). PMID: 31453571.
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    29. Miao Y, Chen Z, Li SC. Functional endoscopy techniques for tracking stem cell fate. Quant Imaging Med Surg. 2019 Mar; 9(3):510-520. PMID: 31032197.
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    30. Li SC, Ge NN. Cancer Subclones Derived from the Patient's Head and Neck Squamous Cell Carcinoma Tumor Stem Cells for the Screening of Personalized Antitumor Immunotherapy and Chemotherapy. Stem Cell Res Ther (Walnut). 2018; 3(1):116-121. PMID: 30972376.
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    31. Li SC, Stucky A, Chen X, Kabeer MH, Loudon WG, Plant AS, Torno L, Nangia CS, Cai J, Zhang G, Zhong JF. Single-cell transcriptomes reveal the mechanism for a breast cancer prognostic gene panel. Oncotarget. 2018 Sep 07; 9(70):33290-33301. PMID: 30279960.
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    32. Chen X, Wen Q, Stucky A, Zeng Y, Gao S, Loudon WG, Ho HW, Kabeer MH, Li SC, Zhang X, Zhong JF. Relapse pathway of glioblastoma revealed by single-cell molecular analysis. Carcinogenesis. 2018 07 03; 39(7):931-936. PMID: 29718126.
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    33. Wu J, Zhang W, Ran Q, Xiang Y, Zhong JF, Li SC, Li Z. The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. Stem Cells Int. 2018; 2018:1540148. PMID: 29765406.
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    34. Li SC, Kabeer MH. Spatiotemporal switching signals for cancer stem cell activation in pediatric origins of adulthood cancer: Towards a watch-and-wait lifetime strategy for cancer treatment. World J Stem Cells. 2018 Feb 26; 10(2):15-22. PMID: 29531638.
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    35. Li SC, Vu LT, Luo JJ, Zhong JF, Li Z, Dethlefs BA, Loudon WG, Kabeer MH. Tissue Elasticity Bridges Cancer Stem Cells to the Tumor Microenvironment Through microRNAs: Implications for a "Watch-and-Wait" Approach to Cancer. Curr Stem Cell Res Ther. 2017; 12(6):455-470. PMID: 28270089.
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    36. Vu LT, Keschrumrus V, Zhang X, Zhong JF, Su Q, Kabeer MH, Loudon WG, Li SC. Correction: Tissue elasticity regulated tumor gene expression: implication for diagnostic biomarkers of primitive neuroectodermal tumor. PLoS One. 2015; 10(5):e0128504. PMID: 25992612.
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    37. Vu LT, Keschrumrus V, Zhang X, Zhong JF, Su Q, Kabeer MH, Loudon WG, Li SC. Tissue elasticity regulated tumor gene expression: implication for diagnostic biomarkers of primitive neuroectodermal tumor. PLoS One. 2015; 10(3):e0120336. PMID: 25774514.
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    38. Li SC, Tachiki LM, Kabeer MH, Dethlefs BA, Anthony MJ, Loudon WG. Cancer genomic research at the crossroads: realizing the changing genetic landscape as intratumoral spatial and temporal heterogeneity becomes a confounding factor. Cancer Cell Int. 2014; 14(1):115. PMID: 25411563.
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    39. Yuan JM, He BL, Yang LY, Guo CJ, Weng SP, Li SC, He JG. Interaction of infectious spleen and kidney necrosis virus ORF119L with PINCH leads to dominant-negative inhibition of integrin-linked kinase and cardiovascular defects in zebrafish. J Virol. 2015 Jan; 89(1):763-75. PMID: 25355883.
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    40. Li SC, Kabeer MH, Vu LT, Keschrumrus V, Yin HZ, Dethlefs BA, Zhong JF, Weiss JH, Loudon WG. Training stem cells for treatment of malignant brain tumors. World J Stem Cells. 2014 Sep 26; 6(4):432-40. PMID: 25258664.
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    41. Jia KT, Wu YY, Liu ZY, Mi S, Zheng YW, He J, Weng SP, Li SC, He JG, Guo CJ. Mandarin fish caveolin 1 interaction with major capsid protein of infectious spleen and kidney necrosis virus and its role in early stages of infection. J Virol. 2013 Mar; 87(6):3027-38. PMID: 23283951.
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    42. Li SC, Yin HZ, Loudon WG, Weiss JH. Cultivating stem cells for treating amyotrophic lateral sclerosis. World J Stem Cells. 2012 Dec 26; 4(12):117-9. PMID: 23516096.
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    43. Li SC, Vu LT, Ho HW, Yin HZ, Keschrumrus V, Lu Q, Wang J, Zhang H, Ma Z, Stover A, Weiss JH, Schwartz PH, Loudon WG. Cancer stem cells from a rare form of glioblastoma multiforme involving the neurogenic ventricular wall. Cancer Cell Int. 2012 Sep 20; 12(1):41. PMID: 22995409.
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    44. Li SC, Acevedo J, Wang L, Jiang H, Luo J, Pestell RG, Loudon WG, Chang AC. Mechanisms for progenitor cell-mediated repair for ischemic heart injury. Curr Stem Cell Res Ther. 2012 Jan; 7(1):2-14. PMID: 21466480.
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    45. Li SC, Lee KL, Luo J. Control dominating subclones for managing cancer progression and posttreatment recurrence by subclonal switchboard signal: implication for new therapies. Stem Cells Dev. 2012 Mar 01; 21(4):503-6. PMID: 21933025.
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    46. Li SC, Lee KL, Luo J, Zhong JF, Loudon WG. Convergence of normal stem cell and cancer stem cell developmental stage: Implication for differential therapies. World J Stem Cells. 2011 Sep 26; 3(9):83-8. PMID: 22007273.
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    47. Li SC, Jin Y, Loudon WG, Song Y, Ma Z, Weiner LP, Zhong JF. Increase developmental plasticity of human keratinocytes with gene suppression. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12793-8. PMID: 21768375.
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    48. Li SC, Han YP, Dethlefs BA, Loudon WG. Therapeutic window, a critical developmental stage for stem cell therapies. Curr Stem Cell Res Ther. 2010 Dec; 5(4):297-3. PMID: 20528752.
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    49. Li SC, Tachiki LM, Luo J, Dethlefs BA, Chen Z, Loudon WG. A biological global positioning system: considerations for tracking stem cell behaviors in the whole body. Stem Cell Rev Rep. 2010 Jun; 6(2):317-33. PMID: 20237964.
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    50. Li SC, Zhong JF. Twisting immune responses for allogeneic stem cell therapy. World J Stem Cells. 2009 Dec 31; 1(1):30-5. PMID: 20975985.
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    51. Li SC, Wang L, Jiang H, Acevedo J, Chang AC, Loudon WG. Stem cell engineering for treatment of heart diseases: potentials and challenges. Cell Biol Int. 2009 Mar; 33(3):255-67. PMID: 19084605.
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    52. Li SC, Loudon WG. A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors. Cancer Cell Int. 2008 May 22; 8:9. PMID: 18498656.
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