Administration, Topical

"Administration, Topical" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.

Descriptor ID	D000287
MeSH Number(s)	E02.319.267.120
Concept/Terms	Administration, Topical Administration, Topical Drug Administration, Topical Topical Drug Administration Topical Administration Administrations, Topical Topical Administrations Administration, Topical Drug Administrations, Topical Drug Drug Administrations, Topical Topical Drug Administrations

Below are MeSH descriptors whose meaning is more general than "Administration, Topical".

Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Therapeutics [E02]
Drug Therapy [E02.319]
Drug Administration Routes [E02.319.267]
Administration, Topical [E02.319.267.120]

Below are MeSH descriptors whose meaning is related to "Administration, Topical".

Below are MeSH descriptors whose meaning is more specific than "Administration, Topical".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Administration, Topical" by people in this website by year, and whether "Administration, Topical" was a major or minor topic of these publications.

Bar chart showing 96 publications over 26 distinct years, with a maximum of 7 publications in 2003 and 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	4	4
1997	0	6	6
1998	0	2	2
1999	0	2	2
2000	0	5	5
2001	0	1	1
2002	0	5	5
2003	0	7	7
2004	0	4	4
2005	0	3	3
2006	0	2	2
2008	0	2	2
2009	0	5	5
2010	0	5	5
2011	0	2	2
2012	0	6	6
2013	0	7	7
2014	0	3	3
2015	0	2	2
2016	0	4	4
2017	1	3	4
2018	0	1	1
2019	0	2	2
2020	0	4	4
2021	0	3	3
2024	0	5	5

Below are the most recent publications written about "Administration, Topical" by people in Profiles.

Mu W, Lizcano JD, Xu B, Li S, Zhang X, Parvizi J, Cao L. Dynamics of Synovial Fluid Markers Following Single-Stage Exchange and Debridement, Antibiotics, and Implant Retention Procedure With Topical Antibiotic Infusion in Treating Periprosthetic Joint Infection. J Arthroplasty. 2025 06; 40(6):1613-1621.

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Chu AWL, Rayner DG, Chu X, Chen L, Dong AYH, Waserman S, Baker DR, Sheikh J, Moellman J, Lang DM, Ben-Shoshan M, Mathur SK, Beck LA, Khan DA, Oliver ET, Asiniwasis RN, Chan J, Cole EF, Trayes KP, Frazier WT, Runyon L, Wheeler KE, Eftekhari S, Gardner DD, Winders T, Bernstein JA, Saini SS, Chu DK. Topical corticosteroids for hives and itch (urticaria): Systematic review and Bayesian meta-analysis of randomized trials. Ann Allergy Asthma Immunol. 2024 10; 133(4):437-444.e18.

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Flammer LJ, Ellis H, Rivers N, Caronia L, Ghidewon MY, Christensen CM, Jiang P, Breslin PAS, Tordoff MG. Topical application of a P2X2/P2X3 purine receptor inhibitor suppresses the bitter taste of medicines and other taste qualities. Br J Pharmacol. 2024 Sep; 181(17):3282-3299.

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Duffy A, Naimi B, Garvey E, Hunter S, Kumar A, Kahn C, Farquhar D, D'Souza G, Rawson N, Dalton P, Toskala E, Rabinowitz M, Rosen M, Nyquist G, Rosen D. Topical platelet-rich plasma as a possible treatment for olfactory dysfunction-A randomized controlled trial. Int Forum Allergy Rhinol. 2024 09; 14(9):1455-1464.

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Leventer I, Singh H, Pashaee B, Raimondo CD, Khakh CK, Martin JL, Acharya B, Zhang Q, Lally SE, Shields CL. Topical 5-fluorouracil 1% for moderate to extensive ocular surface squamous neoplasia in 73 consecutive patients: Primary versus secondary treatment. Asia Pac J Ophthalmol (Phila). 2024 Mar-Apr; 13(2):100052.

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Shields CL, Paulose SA, Yaghy A, Dalvin LA, Constantinescu AB, Lally SE, Shields JA. Ocular Surface Squamous Neoplasia Managed With Primary Interferon a2b: A Comparative Analysis of 212 Tumors in Smokers Versus Nonsmokers. Cornea. 2021 Nov 01; 40(11):1387-1394.

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Kim HJ, Alluri R, Stein D, Lebl D, Huang R, Lafage R, Bennett T, Lafage V, Albert T. Effect of Topical Steroid on Swallowing Following ACDF: Results of a Prospective Double-Blind Randomized Control Trial. Spine (Phila Pa 1976). 2021 Apr 01; 46(7):413-420.

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Shields CL, Constantinescu AB, Paulose SA, Yaghy A, Dalvin LA, Shields JA, Lally SE. Primary treatment of ocular surface squamous neoplasia with topical interferon alpha-2b: Comparative analysis of outcomes based on original tumor configuration. Indian J Ophthalmol. 2021 03; 69(3):563-567.

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Bielory L, Tabliago NRA. Flavonoid and cannabinoid impact on the ocular surface. Curr Opin Allergy Clin Immunol. 2020 10; 20(5):482-492.

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Cullifer RM, Makai G, Pacis M, Huynh T. Topical hemostatic and tissue-sealing agents in gynecologic surgery. Curr Opin Obstet Gynecol. 2020 08; 32(4):285-291.

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