"Amantadine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An antiviral that is used in the prophylactic or symptomatic treatment of influenza A. It is also used as an antiparkinsonian agent, to treat extrapyramidal reactions, and for postherpetic neuralgia. The mechanisms of its effects in movement disorders are not well understood but probably reflect an increase in synthesis and release of dopamine, with perhaps some inhibition of dopamine uptake.
| Descriptor ID |
D000547
|
| MeSH Number(s) |
D02.455.426.100.050.035
|
| Concept/Terms |
Amantadine- Amantadine
- 1-Aminoadamantane
- 1 Aminoadamantane
- Adamantylamine
Amanta-Sulfate-AZU- Amanta-Sulfate-AZU
- Amanta Sulfate AZU
- AmantaSulfateAZU
- Amantadin AZU
- AZU, Amantadin
|
Below are MeSH descriptors whose meaning is more general than "Amantadine".
Below are MeSH descriptors whose meaning is more specific than "Amantadine".
This graph shows the total number of publications written about "Amantadine" by people in this website by year, and whether "Amantadine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 2 | 2 |
| 2007 | 2 | 2 | 4 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Amantadine" by people in Profiles.
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Hauser RA, Kremens DE, Elmer LW, Kreitzman DL, Walsh RR, Johnson R, Howard R, Nguyen JT, Patni R. Prevalence of Dyskinesia and OFF by 30-Minute Intervals Through the Day and Assessment of Daily Episodes of Dyskinesia and OFF: Novel Analyses of Diary Data from Gocovri Pivotal Trials. J Parkinsons Dis. 2019; 9(3):591-600.
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El-Shesheny R, Bagato O, Kandeil A, Mostafa A, Mahmoud SH, Hassanneen HM, Webby RJ, Ali MA, Kayali G. Re-emergence of amantadine-resistant variants among highly pathogenic avian influenza H5N1 viruses in Egypt. Infect Genet Evol. 2016 12; 46:102-109.
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Manzotti G, Parenti S, Ferrari-Amorotti G, Soliera AR, Cattelani S, Montanari M, Cavalli D, Ertel A, Grande A, Calabretta B. Monocyte-macrophage differentiation of acute myeloid leukemia cell lines by small molecules identified through interrogation of the Connectivity Map database. Cell Cycle. 2015; 14(16):2578-89.
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Whyte J, Nordenbo AM, Kalmar K, Merges B, Bagiella E, Chang H, Yablon S, Cho S, Hammond F, Khademi A, Giacino J. Medical complications during inpatient rehabilitation among patients with traumatic disorders of consciousness. Arch Phys Med Rehabil. 2013 Oct; 94(10):1877-83.
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Giacino JT, Whyte J, Bagiella E, Kalmar K, Childs N, Khademi A, Eifert B, Long D, Katz DI, Cho S, Yablon SA, Luther M, Hammond FM, Nordenbo A, Novak P, Mercer W, Maurer-Karattup P, Sherer M. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med. 2012 Mar 01; 366(9):819-26.
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Manini AF, Raspberry D, Hoffman RS, Nelson LS. QT prolongation and Torsades de Pointes following overdose of ziprasidone and amantadine. J Med Toxicol. 2007 Dec; 3(4):178-81.
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Buxbaum LJ, Ferraro M, Whyte J, Gershkoff A, Coslett HB. Amantadine treatment of hemispatial neglect: a double-blind, placebo-controlled study. Am J Phys Med Rehabil. 2007 Jul; 86(7):527-37.
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Whyte J. Treatments to enhance recovery from the vegetative and minimally conscious states: ethical issues surrounding efficacy studies. Am J Phys Med Rehabil. 2007 Feb; 86(2):86-92.
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Axelrod S, Bielory L. Beta2-agonists and paresthesias in multiple sclerosis. Ann Allergy Asthma Immunol. 2007 Jan; 98(1):100.
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Herrine SK, Brown RS, Bernstein DE, Ondovik MS, Lentz E, Te H. Peginterferon alpha-2a combination therapies in chronic hepatitis C patients who relapsed after or had a viral breakthrough on therapy with standard interferon alpha-2b plus ribavirin: a pilot study of efficacy and safety. Dig Dis Sci. 2005 Apr; 50(4):719-26.