Anti-Inflammatory Agents, Non-Steroidal

"Anti-Inflammatory Agents, Non-Steroidal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Anti-inflammatory agents that are non-steroidal in nature. In addition to anti-inflammatory actions, they have analgesic, antipyretic, and platelet-inhibitory actions.They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins. Inhibition of prostaglandin synthesis accounts for their analgesic, antipyretic, and platelet-inhibitory actions; other mechanisms may contribute to their anti-inflammatory effects.

Descriptor ID	D000894
MeSH Number(s)	D27.505.696.663.850.014.040.500 D27.505.954.158.030 D27.505.954.329.030
Concept/Terms	Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal Antiinflammatory Agents, Non Steroidal NSAIDs Non-Steroidal Anti-Inflammatory Agents Non Steroidal Anti Inflammatory Agents Nonsteroidal Anti-Inflammatory Agents Nonsteroidal Anti Inflammatory Agents Anti Inflammatory Agents, Nonsteroidal Antiinflammatory Agents, Nonsteroidal Nonsteroidal Antiinflammatory Agents Analgesics, Anti-Inflammatory Analgesics, Anti-Inflammatory Anti-Inflammatory Analgesics Aspirin-Like Agents Aspirin-Like Agents Aspirin Like Agents

Below are MeSH descriptors whose meaning is more general than "Anti-Inflammatory Agents, Non-Steroidal".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Peripheral Nervous System Agents [D27.505.696.663]
Sensory System Agents [D27.505.696.663.850]
Analgesics [D27.505.696.663.850.014]
Analgesics, Non-Narcotic [D27.505.696.663.850.014.040]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.696.663.850.014.040.500]
Therapeutic Uses [D27.505.954]
Anti-Inflammatory Agents [D27.505.954.158]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.158.030]
Antirheumatic Agents [D27.505.954.329]
Anti-Inflammatory Agents, Non-Steroidal [D27.505.954.329.030]

Below are MeSH descriptors whose meaning is related to "Anti-Inflammatory Agents, Non-Steroidal".

Below are MeSH descriptors whose meaning is more specific than "Anti-Inflammatory Agents, Non-Steroidal".

Anti-Inflammatory Agents, Non-Steroidal
Cyclooxygenase Inhibitors

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in this website by year, and whether "Anti-Inflammatory Agents, Non-Steroidal" was a major or minor topic of these publications.

Bar chart showing 257 publications over 30 distinct years, with a maximum of 19 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	2	1	3
1997	4	2	6
1998	1	2	3
1999	2	4	6
2000	3	1	4
2001	2	2	4
2002	5	4	9
2003	6	5	11
2004	3	1	4
2005	2	8	10
2006	4	8	12
2007	4	7	11
2008	9	10	19
2009	10	5	15
2010	4	6	10
2011	6	5	11
2012	9	5	14
2013	7	7	14
2014	2	8	10
2015	8	7	15
2016	4	2	6
2017	7	6	13
2018	7	3	10
2019	2	3	5
2020	4	4	8
2021	5	6	11
2022	1	2	3
2023	1	4	5
2024	1	0	1
2025	1	3	4

Below are the most recent publications written about "Anti-Inflammatory Agents, Non-Steroidal" by people in Profiles.

Hanselman EC, Harmon CP, Deng D, Sywanycz SM, Caronia L, Jiang P, Breslin PAS. Ibuprofen inhibits human sweet taste and glucose detection implicating an additional mechanism of metabolic disease risk reduction. Br J Pharmacol. 2025 Jun; 182(12):2682-2693.

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Paruchuri SS, Mahmoudzadeh R, Wheeler S, Randolph J. Prevention and management of postcataract cystoid macular edema. Curr Opin Ophthalmol. 2025 May 01; 36(3):182-188.

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Kumchai H, Taub DI, Tomlinson RE. Randomized, Placebo-Controlled Pilot Study of Naproxen During Dental Implant Osseointegration. Clin Exp Dent Res. 2025 02; 11(1):e70065.

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John G H, Joseph Albert A, Chen AF, Ilyas AM. Reducing Opioid Use in Orthopaedic Surgery. Instr Course Lect. 2025; 74:313-322.

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Lambrechts MJ, D'Antonio ND, Heard JC, Yalla G, Karamian BA, Markova DZ, Kepler CK. The Inhibitory Effect of NSAIDs and Opioids on Spinal Fusion: An Animal Model. Spine (Phila Pa 1976). 2024 Jun 15; 49(12):821-828.

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Chiang CC, Fang X, Horvath Z, Cadiou F, Urani A, Poh W, Narimatsu H, Cheng Y, Dodick DW. Simultaneous Comparisons of 25 Acute Migraine Medications Based on 10 Million Users' Self-Reported Records From a Smartphone Application. Neurology. 2023 12 12; 101(24):e2560-e2570.

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Merola JF, Parish LC, Guenther L, Lynde C, Lacour JP, Staubach P, Cheng S, Paris M, Picard H, Deignan C, Jardon S, Chen M, Papp KA. Efficacy and safety of apremilast in patients with moderate-to-severe genital psoriasis: Results from DISCREET, a phase 3 randomized, double-blind, placebo-controlled trial. J Am Acad Dermatol. 2024 03; 90(3):485-493.

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Bachert C, Laidlaw TM, Cho SH, Mullol J, Swanson BN, Naimi S, Classe M, Harel S, Jagerschmidt A, Laws E, Ruddy M, Praestgaard A, Amin N, Mannent LP. Effect of Dupilumab on Type 2 Biomarkers in Chronic Rhinosinusitis With Nasal Polyps: SINUS-52 Study Results. Ann Otol Rhinol Laryngol. 2023 Dec; 132(12):1649-1661.

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Kachooei A, Hester W, Gaston T, Corr D, Winters B, Raikin S, Daniel J. Effect of Postoperative Ketorolac Administration on the Union Rate Following First Metatarsophalangeal Joint Arthrodesis. Foot Ankle Spec. 2025 Aug; 18(4):381-388.

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Giordano T, Durkin A, Simi A, Shannon M, Dailey J, Facey H, Ballester L, Wetmore RF, Germiller JA. High-Dose Celecoxib for Pain After Pediatric Tonsillectomy: A Randomized Controlled Trial. Otolaryngol Head Neck Surg. 2023 02; 168(2):218-226.

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