"Antifibrinolytic Agents" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Agents that prevent fibrinolysis or lysis of a blood clot or thrombus. Several endogenous antiplasmins are known. The drugs are used to control massive hemorrhage and in other coagulation disorders.
| Descriptor ID |
D000933
|
| MeSH Number(s) |
D27.505.519.421.500 D27.505.954.502.270.463.091
|
| Concept/Terms |
Plasmin Inhibitors- Plasmin Inhibitors
- Inhibitors, Plasmin
- Antiplasmins
- Plasmin Inhibitor
- Inhibitor, Plasmin
|
Below are MeSH descriptors whose meaning is more general than "Antifibrinolytic Agents".
Below are MeSH descriptors whose meaning is more specific than "Antifibrinolytic Agents".
This graph shows the total number of publications written about "Antifibrinolytic Agents" by people in this website by year, and whether "Antifibrinolytic Agents" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2017 | 2 | 0 | 2 |
| 2018 | 6 | 0 | 6 |
| 2019 | 1 | 2 | 3 |
| 2020 | 3 | 0 | 3 |
| 2021 | 2 | 0 | 2 |
| 2023 | 1 | 0 | 1 |
| 2024 | 6 | 1 | 7 |
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Below are the most recent publications written about "Antifibrinolytic Agents" by people in Profiles.
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Leal J, Kugelman DN, Ward SA, Wixted CM, Lajam CM, Schwarzkopf R, Seyler TM. Total hip arthroplasty was found to be safe in Jehovah's Witness patients: a multi-centered matched study. Arch Orthop Trauma Surg. 2024 Dec 31; 145(1):103.
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Hohmann AL, Wilson AE, Schulte DM, Casambre FD, Della Valle CJ, Lonner JH, Fillingham YA. Fragility Index Analysis of the 2018 Clinical Practice Guidelines on Tranexamic Acid Use in Total Joint Arthroplasty. J Arthroplasty. 2025 03; 40(3):573-577.e3.
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Leal J, Kugelman DN, Ward SA, Wixted CM, Lajam CM, Seyler TM, Schwarzkopf R. Tranexamic Acid Led to Improved Safety of Total Knee Arthroplasty in Jehovah's Witness Patients: A Multicentered Matched Study. J Arthroplasty. 2025 02; 40(2):409-415.
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Marous CL, Wladis EJ. Reply Re: "Effects of Preoperative Intravenous Versus Subcutaneous Tranexamic Acid on Postoperative Periorbital Ecchymosis and Edema Following Upper Eyelid Blepharoplasty: A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Comparative Study". Ophthalmic Plast Reconstr Surg. 2024 Jul-Aug 01; 40(4):471.
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Meghpara M, Goh GS, Fillingham YA. Response to Letter to the Editor on "Does the Use of Tranexamic Acid in Patients Who Have Preoperative Coagulopathy Undergoing Total Joint Arthroplasty Normalize Their Risk of Complications? A Matched Equivalence Analysis". J Arthroplasty. 2024 06; 39(6):e44-e45.
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Marous CL, Farhat OJ, Cefalu M, Rothschild MI, Alapati S, Wladis EJ. Effects of Preoperative Intravenous Versus Subcutaneous Tranexamic Acid on Postoperative Periorbital Ecchymosis and Edema Following Upper Eyelid Blepharoplasty: A Prospective, Randomized, Double-Blinded, Placebo-Controlled, Comparative Study. Ophthalmic Plast Reconstr Surg. 2024 Sep-Oct 01; 40(5):523-532.
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Musmar B, Orscelik A, Salim H, Adeeb N, Spellicy S, Abdelgadir J, Azar J, Cuellar-Saenz HH, Guthikonda B, Jabbour P, Hasan D. Efficacy and safety of tranexamic acid in the management of chronic subdural hematoma: a systematic review and meta-analysis. J Neurosurg. 2024 10 01; 141(4):945-954.
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Meghpara MM, Goh GS, Ciesielka KA, Fillingham YA. Does the Use of Tranexamic Acid in Patients Who Have Preoperative Coagulopathy Undergoing Total Joint Arthroplasty Normalize Their Risk of Complications? A Matched Equivalence Analysis. J Arthroplasty. 2023 11; 38(11):2264-2268.
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Goh GS, D'Amore T, Lonner JH, Fillingham YA. Tranexamic Acid is Associated With Decreasing the Risk of Complications in Patients Undergoing Arthroplasty With Preoperative Coagulopathy. J Arthroplasty. 2021 12; 36(12):3864-3869.e1.
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Martinez Manzano JM, Lo KB, Patarroyo-Aponte G, Azmaiparashvili Z. The use of intravenous tranexamic acid for patients with angiotensin-converting enzyme inhibitor-induced angioedema: A case series. Ann Allergy Asthma Immunol. 2021 06; 126(6):725-726.