3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester
"3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A dihydropyridine derivative, which, in contrast to NIFEDIPINE, functions as a calcium channel agonist. The compound facilitates Ca2+ influx through partially activated voltage-dependent Ca2+ channels, thereby causing vasoconstrictor and positive inotropic effects. It is used primarily as a research tool.
| Descriptor ID |
D001498
|
| MeSH Number(s) |
D03.383.725.203.600 D03.383.725.547.900
|
| Concept/Terms |
Bay-R-5417- Bay-R-5417
- Bay R 5417
- BayR5417
- Bay R5417
- R5417, Bay
Bay-K-8644- Bay-K-8644
- Bay K 8644
- BayK8644
- Bay-K8644
- Bay K8644
- BK-8644
- BK 8644
- BK8644
|
Below are MeSH descriptors whose meaning is more general than "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester".
Below are MeSH descriptors whose meaning is more specific than "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester".
This graph shows the total number of publications written about "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" by people in this website by year, and whether "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester" by people in Profiles.
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Sicouri S, Timothy KW, Zygmunt AC, Glass A, Goodrow RJ, Belardinelli L, Antzelevitch C. Cellular basis for the electrocardiographic and arrhythmic manifestations of Timothy syndrome: effects of ranolazine. Heart Rhythm. 2007 May; 4(5):638-47.
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Garcia MC, Sanchez JA, Sharma VK, Sheu SS. Extracellular heparin inhibits Ca2+ transients and contraction in mammalian cardiac myocytes. Pflugers Arch. 1995 Nov; 431(1):84-90.
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Sicouri S, Antzelevitch C. Afterdepolarizations and triggered activity develop in a select population of cells (M cells) in canine ventricular myocardium: the effects of acetylstrophanthidin and Bay K 8644. Pacing Clin Electrophysiol. 1991 Nov; 14(11 Pt 2):1714-20.
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Enyeart JJ, Sheu SS, Hinkle PM. Dihydropyridine modulators of voltage-sensitive Ca2+ channels specifically regulate prolactin production by GH4C1 pituitary tumor cells. J Biol Chem. 1987 Mar 05; 262(7):3154-9.