"Benzo(a)pyrene" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.
| Descriptor ID |
D001564
|
| MeSH Number(s) |
D02.455.426.559.847.799.306.300 D04.615.799.306.300
|
| Concept/Terms |
Benzo(a)pyrene- Benzo(a)pyrene
- 3,4-Benzpyrene
- 3,4 Benzpyrene
- 3,4-Benzopyrene
- 3,4 Benzopyrene
|
Below are MeSH descriptors whose meaning is more general than "Benzo(a)pyrene".
Below are MeSH descriptors whose meaning is more specific than "Benzo(a)pyrene".
This graph shows the total number of publications written about "Benzo(a)pyrene" by people in this website by year, and whether "Benzo(a)pyrene" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 1 | 2 |
| 2007 | 0 | 1 | 1 |
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Below are the most recent publications written about "Benzo(a)pyrene" by people in Profiles.
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Bassi DE, Klein-Szanto AJ. Carcinogen-induced animal models of head and neck squamous cell carcinoma. Curr Protoc Pharmacol. 2007 Jun; Chapter 14:Unit 14.2.
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Zhang SY, Liu SC, Goodrow T, Morris R, Klein-Szanto AJ. Increased expression of G1 cyclins and cyclin-dependent kinases during tumor progression of chemically induced mouse skin neoplasms. Mol Carcinog. 1997 Mar; 18(3):142-52.
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Mitsunaga S, Clapper M, Litwin S, Watts P, Bauer B, Klein-Szanto AJ. Chemopreventive effect of difluoromethylornithine (DFMO) on mouse skin squamous cell carcinomas induced by benzo(a)pyrene. J Cell Biochem Suppl. 1997; 28-29:81-9.
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Mitsunaga SI, Zhang SY, Ruggeri BA, Gimenez-Conti I, Robles AI, Conti CJ, Klein-Szanto AJ. Positive immunohistochemical staining of p53 and cyclin D in advanced mouse skin tumors, but not in precancerous lesions produced by benzo[a]pyrene. Carcinogenesis. 1995 Jul; 16(7):1629-35.
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Zhang SY, Bauer B, Mitsunaga S, Goodrow TL, Klein-Szanto AJ. Lack of concordant p53 mutations in some paired primary and metastatic mouse squamous cell carcinomas induced by chemical carcinogenesis. Mol Carcinog. 1995 Feb; 12(2):77-81.
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Ruggeri BA, Bauer B, Zhang SY, Klein-Szanto AJ. Murine squamous cell carcinoma cell lines produced by a complete carcinogenesis protocol with benzo[a]pyrene exhibit characteristic p53 mutations and the absence of H-ras and cyl 1/cyclin D1 abnormalities. Carcinogenesis. 1994 Aug; 15(8):1613-9.
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Ruggeri B, DiRado M, Zhang SY, Bauer B, Goodrow T, Klein-Szanto AJ. Benzo[a]pyrene-induced murine skin tumors exhibit frequent and characteristic G to T mutations in the p53 gene. Proc Natl Acad Sci U S A. 1993 Feb 01; 90(3):1013-7.
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Klein-Szanto AJ, Ura H, Momiki S, Bonfil D, Litwin S. Effects of formaldehyde on xenotransplanted human respiratory epithelium. Res Rep Health Eff Inst. 1992 Jul; (51):1-17; discussion 19-27.