"Bromodeoxyuridine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A nucleoside that substitutes for thymidine in DNA and thus acts as an antimetabolite. It causes breaks in chromosomes and has been proposed as an antiviral and antineoplastic agent. It has been given orphan drug status for use in the treatment of primary brain tumors.
| Descriptor ID |
D001973
|
| MeSH Number(s) |
D03.383.742.680.852.300.150 D13.570.230.430.196 D13.570.685.852.300.150
|
| Concept/Terms |
Bromodeoxyuridine- Bromodeoxyuridine
- Bromouracil Deoxyriboside
- Deoxyriboside, Bromouracil
- 5-Bromo-2'-deoxyuridine
- 5 Bromo 2' deoxyuridine
- BrdU
- BUdR
- 5-Bromodeoxyuridine
- 5 Bromodeoxyuridine
- Broxuridine
|
Below are MeSH descriptors whose meaning is more general than "Bromodeoxyuridine".
Below are MeSH descriptors whose meaning is more specific than "Bromodeoxyuridine".
This graph shows the total number of publications written about "Bromodeoxyuridine" by people in this website by year, and whether "Bromodeoxyuridine" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 3 | 3 |
| 2005 | 0 | 3 | 3 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Bromodeoxyuridine" by people in Profiles.
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Fenstermaker TK, Sun G, Mazo A, Petruk S. A Proximity Ligation-Based Method to Detect RNA-DNA Association. Methods Mol Biol. 2019; 2008:121-129.
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Yeung J, Ha TJ, Swanson DJ, Goldowitz D. A Novel and Multivalent Role of Pax6 in Cerebellar Development. J Neurosci. 2016 08 31; 36(35):9057-69.
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Tong Y, Ha TJ, Liu L, Nishimoto A, Reiner A, Goldowitz D. Spatial and temporal requirements for huntingtin (Htt) in neuronal migration and survival during brain development. J Neurosci. 2011 Oct 12; 31(41):14794-9.
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Ward KN, Coleman JL, Clinnin K, Fahrbach S, Rueppell O. Age, caste, and behavior determine the replicative activity of intestinal stem cells in honeybees (Apis mellifera L.). Exp Gerontol. 2008 Jun; 43(6):530-7.
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Butchbach ME, Edwards JD, Schussler KR, Burghes AH. A novel method for oral delivery of drug compounds to the neonatal SMNDelta7 mouse model of spinal muscular atrophy. J Neurosci Methods. 2007 Apr 15; 161(2):285-90.
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Swanson DJ, Tong Y, Goldowitz D. Disruption of cerebellar granule cell development in the Pax6 mutant, Sey mouse. Brain Res Dev Brain Res. 2005 Dec 07; 160(2):176-93.
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Smeyne M, Jiao Y, Shepherd KR, Smeyne RJ. Glia cell number modulates sensitivity to MPTP in mice. Glia. 2005 Nov 01; 52(2):144-52.
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Schneider JS, Anderson DW, Wade TV, Smith MG, Leibrandt P, Zuck L, Lidsky TI. Inhibition of progenitor cell proliferation in the dentate gyrus of rats following post-weaning lead exposure. Neurotoxicology. 2005 Jan; 26(1):141-5.
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Wen PH, Hof PR, Chen X, Gluck K, Austin G, Younkin SG, Younkin LH, DeGasperi R, Gama Sosa MA, Robakis NK, Haroutunian V, Elder GA. The presenilin-1 familial Alzheimer disease mutant P117L impairs neurogenesis in the hippocampus of adult mice. Exp Neurol. 2004 Aug; 188(2):224-37.
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Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP. Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15; 270(2):393-410.