Capsid

"Capsid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The outer protein protective shell of a virus, which protects the viral nucleic acid.

Descriptor ID	D002213
MeSH Number(s)	A21.249.500.250 B04.950.500.250
Concept/Terms	Capsid Capsid Capsids

Below are MeSH descriptors whose meaning is more general than "Capsid".

Anatomy [A]
Viral Structures [A21]
Virion [A21.249]
Nucleocapsid [A21.249.500]
Capsid [A21.249.500.250]
Organisms [B]
Viruses [B04]
Virion [B04.950]
Nucleocapsid [B04.950.500]
Capsid [B04.950.500.250]

Below are MeSH descriptors whose meaning is related to "Capsid".

Below are MeSH descriptors whose meaning is more specific than "Capsid".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Capsid" by people in this website by year, and whether "Capsid" was a major or minor topic of these publications.

Bar chart showing 31 publications over 18 distinct years, with a maximum of 4 publications in 2017 and 2018

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1997	0	2	2
1998	1	0	1
1999	1	0	1
2000	0	1	1
2002	0	1	1
2004	0	1	1
2005	0	1	1
2015	2	0	2
2016	1	1	2
2017	3	1	4
2018	2	2	4
2019	1	0	1
2020	2	1	3
2021	0	1	1
2022	1	1	2
2023	0	2	2
2024	0	1	1

Below are the most recent publications written about "Capsid" by people in Profiles.

Lokareddy RK, Hou CD, Forti F, Iglesias SM, Li F, Pavlenok M, Horner DS, Niederweis M, Briani F, Cingolani G. Integrative structural analysis of Pseudomonas phage DEV reveals a genome ejection motor. Nat Commun. 2024 10 01; 15(1):8482.

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Fu Q, Lee YS, Green EA, Wang Y, Park SY, Polanco A, Lee KH, Betenbaugh M, McNally D, Yoon S. Design space determination to optimize DNA complexation and full capsid formation in transient rAAV manufacturing. Biotechnol Bioeng. 2023 11; 120(11):3148-3162.

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Sarkar S, Zadrozny KK, Zadorozhnyi R, Russell RW, Quinn CM, Kleinpeter A, Ablan S, Meshkin H, Perilla JR, Freed EO, Ganser-Pornillos BK, Pornillos O, Gronenborn AM, Polenova T. Structural basis of HIV-1 maturation inhibitor binding and activity. Nat Commun. 2023 03 04; 14(1):1237.

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Burdette D, Hyrina A, Song Z, Beran RK, Cheung T, Gilmore S, Kobayashi T, Li L, Liu Y, Niedziela-Majka A, Medley J, Mehra U, Morganelli P, Novikov N, Niu C, Tam D, Tang J, Wang J, Yue Q, Fletcher SP, Holdorf MM, Delaney WE, Feierbach B, Lazerwith S. Characterization of a Novel Capsid Assembly Modulator for the Treatment of Chronic Hepatitis B Virus Infection. Antimicrob Agents Chemother. 2023 01 24; 67(1):e0134822.

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David Hou CF, Swanson NA, Li F, Yang R, Lokareddy RK, Cingolani G. Cryo-EM Structure of a Kinetically Trapped Dodecameric Portal Protein from the Pseudomonas-phage PaP3. J Mol Biol. 2022 05 15; 434(9):167537.

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Perilla JR, Hadden-Perilla JA, Gronenborn AM, Polenova T. Integrative structural biology of HIV-1 capsid protein assemblies: combining experiment and computation. Curr Opin Virol. 2021 06; 48:57-64.

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Xu C, Fischer DK, Rankovic S, Li W, Dick RA, Runge B, Zadorozhnyi R, Ahn J, Aiken C, Polenova T, Engelman AN, Ambrose Z, Rousso I, Perilla JR. Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis. PLoS Biol. 2020 12; 18(12):e3001015.

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Lu M, Russell RW, Bryer AJ, Quinn CM, Hou G, Zhang H, Schwieters CD, Perilla JR, Gronenborn AM, Polenova T. Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nat Struct Mol Biol. 2020 09; 27(9):863-869.

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Piechnik M, Sawamoto K, Ohnishi H, Kawamoto N, Ago Y, Tomatsu S. Evading the AAV Immune Response in Mucopolysaccharidoses. Int J Mol Sci. 2020 May 13; 21(10).

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Dedeo CL, Cingolani G, Teschke CM. Portal Protein: The Orchestrator of Capsid Assembly for the dsDNA Tailed Bacteriophages and Herpesviruses. Annu Rev Virol. 2019 09 29; 6(1):141-160.

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