"Captopril" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A potent and specific inhibitor of PEPTIDYL-DIPEPTIDASE A. It blocks the conversion of ANGIOTENSIN I to ANGIOTENSIN II, a vasoconstrictor and important regulator of arterial blood pressure. Captopril acts to suppress the RENIN-ANGIOTENSIN SYSTEM and inhibits pressure responses to exogenous angiotensin.
| Descriptor ID |
D002216
|
| MeSH Number(s) |
D12.125.072.401.623.270
|
| Concept/Terms |
Captopril- Captopril
- (S)-1-(3-Mercapto-2-methyl-1-oxopropyl)-L-proline
SQ-14,534- SQ-14,534
- SQ 14,534
- SQ14,534
- SQ-14534
- SQ 14534
- SQ14534
SQ-14,225- SQ-14,225
- SQ 14,225
- SQ14,225
- SQ-14225
- SQ 14225
- SQ14225
|
Below are MeSH descriptors whose meaning is more general than "Captopril".
Below are MeSH descriptors whose meaning is more specific than "Captopril".
This graph shows the total number of publications written about "Captopril" by people in this website by year, and whether "Captopril" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 1 | 0 | 1 |
| 1998 | 2 | 0 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 1 | 0 | 1 |
| 2015 | 1 | 0 | 1 |
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Below are the most recent publications written about "Captopril" by people in Profiles.
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Sasongko TH, Nagalla S, Ballas SK. Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease. Cochrane Database Syst Rev. 2015 Jun 04; (6):CD009191.
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Sasongko TH, Nagalla S, Ballas SK. Angiotensin-converting enzyme (ACE) inhibitors for proteinuria and microalbuminuria in people with sickle cell disease. Cochrane Database Syst Rev. 2013 Mar 28; (3):CD009191.
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Patel NP, Pugh ME, Goldberg S, Eiger G. Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report. Am J Crit Care. 2007 Sep; 16(5):520, 518-9.
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De Godoy MA, Rattan S. Angiotensin-converting enzyme and angiotensin II receptor subtype 1 inhibitors restitute hypertensive internal anal sphincter in the spontaneously hypertensive rats. J Pharmacol Exp Ther. 2006 Aug; 318(2):725-34.
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De Godoy MA, Rattan S. Autocrine regulation of internal anal sphincter tone by renin-angiotensin system: comparison with phasic smooth muscle. Am J Physiol Gastrointest Liver Physiol. 2005 Dec; 289(6):G1164-75.
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Metser U, Friedman Z, Even-Sapir E, Samuels D, Kessler A, Graif M. Renal multigated spectral Doppler imaging before and after captopril challenge. Invest Radiol. 2001 Apr; 36(4):234-9.
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Xu X, Rials SJ, Wu Y, Liu T, Marinchak RA, Kowey PR. Effects of captopril treatment of renovascular hypertension on beta-adrenergic modulation of L-type Ca(2+) current. J Pharmacol Exp Ther. 2000 Jan; 292(1):196-200.
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Sacchetti A, Ramoska E, Moakes ME, McDermott P, Moyer V. Effect of ED management on ICU use in acute pulmonary edema. Am J Emerg Med. 1999 Oct; 17(6):571-4.
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Su JZ, Chen DG, Wu KG, Chen SC, Hu WY, Wang XY, Rui HB, Wang HJ, Xu CS. Inhibitory effects of captopril on c-myc expression during left ventricular hypertrophy. Zhongguo Yao Li Xue Bao. 1998 Nov; 19(6):535-40.
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Rials SJ, Xu X, Wu Y, Marinchak RA, Kowey PR. Regression of LV hypertrophy with captopril normalizes membrane currents in rabbits. Am J Physiol. 1998 10; 275(4):H1216-24.