Carbamates

"Carbamates" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Derivatives of carbamic acid, H2NC(=O)OH. Included under this heading are N-substituted and O-substituted carbamic acids. In general carbamate esters are referred to as urethanes, and polymers that include repeating units of carbamate are referred to as POLYURETHANES. Note however that polyurethanes are derived from the polymerization of ISOCYANATES and the singular term URETHANE refers to the ethyl ester of carbamic acid.

Descriptor ID	D002219
MeSH Number(s)	D02.241.081.251
Concept/Terms	Carbamates Carbamates Carbamic Acids Carbamic Acids Acids, Carbamic Aminoformic Acids Acids, Aminoformic

Below are MeSH descriptors whose meaning is more general than "Carbamates".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Carbamates [D02.241.081.251]

Below are MeSH descriptors whose meaning is related to "Carbamates".

Below are MeSH descriptors whose meaning is more specific than "Carbamates".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Carbamates" by people in this website by year, and whether "Carbamates" was a major or minor topic of these publications.

Bar chart showing 27 publications over 16 distinct years, with a maximum of 3 publications in 2015 and 2021 and 2023

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	0	1	1
2009	2	0	2
2010	2	0	2
2012	1	1	2
2013	2	0	2
2014	1	0	1
2015	3	0	3
2017	0	1	1
2018	1	0	1
2020	2	0	2
2021	1	2	3
2022	0	1	1
2023	0	3	3
2024	1	0	1
2025	1	0	1

Below are the most recent publications written about "Carbamates" by people in Profiles.

Loushy I, Goldstein L, Devlin K, Volski A, Fletman E, Alcala-Zermeno JL, Porreca L, Sperling MR. Real-world use of cenobamate in adults: Efficacy and predictors of treatment response. Epilepsia. 2025 May; 66(5):1492-1504.

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Tartaglia G, Fuentes I, Patel N, Varughese A, Israel LE, Park PH, Alexander MH, Poojan S, Cao Q, Solomon B, Padron ZM, Dyer JA, Mellerio JE, McGrath JA, Palisson F, Salas-Alanis J, Han L, South AP. Antiviral drugs prolong survival in murine recessive dystrophic epidermolysis bullosa. EMBO Mol Med. 2024 04; 16(4):870-884.

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Rosenfeld WE, Ferrari L, Kerr WT, Sperling MR. Sudden unexpected death in epilepsy during cenobamate clinical development. Epilepsia. 2023 08; 64(8):2108-2115.

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Klein P, Krauss GL, Steinhoff BJ, Devinsky O, Sperling MR. Failure to use new breakthrough treatments for epilepsy. Epilepsia. 2023 06; 64(6):1458-1465.

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Kotani K, Enomoto M, Uchida-Kobayashi S, Tamori A, Yukawa-Muto Y, Odagiri N, Motoyama H, Kozuka R, Kawamura E, Hagihara A, Fujii H, Kageyama K, Yamamoto A, Yoshida A, Higashiyama S, Kawabe J, Kawada N. Short-term hepatocyte function and portal hypertension outcomes of sofosbuvir/velpatasvir for decompensated hepatitis C-related cirrhosis. J Gastroenterol. 2023 04; 58(4):394-404.

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Abou-Khalil B, Aboumatar S, Klein P, Krauss GL, Sperling MR, Rosenfeld WE. Efficacy of cenobamate for uncontrolled focal seizures in patients with previous epilepsy-related surgery: Post hoc analysis of a phase 3, multicenter, open-label study. Epilepsy Res. 2022 08; 184:106952.

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Rosenfeld WE, Abou-Khalil B, Aboumatar S, Bhatia P, Biton V, Krauss GL, Sperling MR, Vossler DG, Klein P, Wechsler R. Post hoc analysis of a phase 3, multicenter, open-label study of cenobamate for treatment of uncontrolled focal seizures: Effects of dose adjustments of concomitant antiseizure medications. Epilepsia. 2021 12; 62(12):3016-3028.

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Sperling MR, Abou-Khalil B, Aboumatar S, Bhatia P, Biton V, Klein P, Krauss GL, Vossler DG, Wechsler R, Ferrari L, Grall M, Rosenfeld WE. Efficacy of cenobamate for uncontrolled focal seizures: Post hoc analysis of a Phase 3, multicenter, open-label study. Epilepsia. 2021 12; 62(12):3005-3015.

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French JA, Chung SS, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Kamin M. Long-term safety of adjunctive cenobamate in patients with uncontrolled focal seizures: Open-label extension of a randomized clinical study. Epilepsia. 2021 09; 62(9):2142-2150.

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Chung SS, French JA, Kowalski J, Krauss GL, Lee SK, Maciejowski M, Rosenfeld WE, Sperling MR, Mizne S, Kamin M. Randomized phase 2 study of adjunctive cenobamate in patients with uncontrolled focal seizures. Neurology. 2020 06 02; 94(22):e2311-e2322.

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