Cefazolin

"Cefazolin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A semisynthetic cephalosporin analog with broad-spectrum antibiotic action due to inhibition of bacterial cell wall synthesis. It attains high serum levels and is excreted quickly via the urine.

Descriptor ID	D002437
MeSH Number(s)	D02.065.589.099.249.160 D02.886.665.074.160 D03.633.100.300.249.160
Concept/Terms	Cefazolin Cefazolin Cephazolin Cefamedin Cefamedin Cefamezine Cefamezine Cephamezine Gramaxin Gramaxin Kefzol Kefzol Totacef Totacef Ancef Ancef Cefazolin Sodium Cefazolin Sodium Sodium, Cefazolin Sodium Cephazolin Cephazolin, Sodium Cephazolin Sodium Sodium, Cephazolin

Below are MeSH descriptors whose meaning is more general than "Cefazolin".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Amides [D02.065]
Lactams [D02.065.589]
beta-Lactams [D02.065.589.099]
Cephalosporins [D02.065.589.099.249]
Cefazolin [D02.065.589.099.249.160]
Sulfur Compounds [D02.886]
Thiazines [D02.886.665]
Cephalosporins [D02.886.665.074]
Cefazolin [D02.886.665.074.160]
Heterocyclic Compounds [D03]
Heterocyclic Compounds, Fused-Ring [D03.633]
Heterocyclic Compounds, 2-Ring [D03.633.100]
beta-Lactams [D03.633.100.300]
Cephalosporins [D03.633.100.300.249]
Cefazolin [D03.633.100.300.249.160]

Below are MeSH descriptors whose meaning is related to "Cefazolin".

Below are MeSH descriptors whose meaning is more specific than "Cefazolin".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Cefazolin" by people in this website by year, and whether "Cefazolin" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 2 publications in 2000 and 2001 and 2013 and 2015 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
2000	1	1	2
2001	1	1	2
2008	0	1	1
2013	1	1	2
2015	2	0	2
2017	1	0	1
2018	1	0	1
2019	1	1	2
2020	0	1	1
2021	1	0	1
2022	1	0	1
2024	1	0	1

Below are the most recent publications written about "Cefazolin" by people in Profiles.

Carter M, Narayanan R, Toci G, Huang R, Dalton J, Tomlak A, Lee Y, Mumtaz S, Sabitsky M, Pasha A, Vanichkachorn A, Kim A, Syal A, Kurd M, Kaye ID, Canseco J, Hilibrand A, Vaccaro A, Schroeder G, Kepler C. Lumbar Fusion Surgical Prophylaxis Using Cefazolin Versus Vancomycin in the Penicillin-Allergic Patient. Spine (Phila Pa 1976). 2025 Sep 15; 50(18):1267-1272.

View in: PubMed
Karamian BA, Toci GR, Lambrechts MJ, Siegel N, Sherman M, Canseco JA, Hilibrand AS, Kepler CK, Vaccaro AR, Schroeder GD. Cefazolin prophylaxis in spine surgery: patients are frequently underdosed and at increased risk for infection. Spine J. 2022 09; 22(9):1442-1450.

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Mraovic B, Timko NJ, Simurina T. Dual Allergy to Penicillin and Cefazolin-Does Anaphylaxis Matter? JAMA Surg. 2021 12 01; 156(12):1184.

View in: PubMed
Durrani AF, Atta S, Bhat AK, Mammen A, Dhaliwal D, Kowalski RP, Jhanji V. Methicillin-Resistant Staphylococcus aureus Keratitis: Initial Treatment, Risk Factors, Clinical Features, and Treatment Outcomes. Am J Ophthalmol. 2020 06; 214:119-126.

View in: PubMed
Godfrey J, Choi PD, Shabtai L, Nossov SB, Williams A, Lindberg AW, Silva S, Caird MS, Schur MD, Arkader A. Management of Pediatric Type I Open Fractures in the Emergency Department or Operating Room: A Multicenter Perspective. J Pediatr Orthop. 2019 Aug; 39(7):372-376.

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Tan TL, Shohat N, Rondon AJ, Foltz C, Goswami K, Ryan SP, Seyler TM, Parvizi J. Perioperative Antibiotic Prophylaxis in Total Joint Arthroplasty: A Single Dose Is as Effective as Multiple Doses. J Bone Joint Surg Am. 2019 Mar 06; 101(5):429-437.

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Rondon AJ, Kheir MM, Tan TL, Shohat N, Greenky MR, Parvizi J. Cefazolin Prophylaxis for Total Joint Arthroplasty: Obese Patients Are Frequently Underdosed and at Increased Risk of Periprosthetic Joint Infection. J Arthroplasty. 2018 11; 33(11):3551-3554.

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Kheir MM, Tan TL, Azboy I, Tan DD, Parvizi J. Vancomycin Prophylaxis for Total Joint Arthroplasty: Incorrectly Dosed and Has a Higher Rate of Periprosthetic Infection Than Cefazolin. Clin Orthop Relat Res. 2017 Jul; 475(7):1767-1774.

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Courtney PM, Melnic CM, Zimmer Z, Anari J, Lee GC. Addition of Vancomycin to Cefazolin Prophylaxis Is Associated With Acute Kidney Injury After Primary Joint Arthroplasty. Clin Orthop Relat Res. 2015 Jul; 473(7):2197-203.

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Dastgheyb SS, Hammoud S, Ketonis C, Liu AY, Fitzgerald K, Parvizi J, Purtill J, Ciccotti M, Shapiro IM, Otto M, Hickok NJ. Staphylococcal persistence due to biofilm formation in synovial fluid containing prophylactic cefazolin. Antimicrob Agents Chemother. 2015 Apr; 59(4):2122-8.

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