Central Nervous System Depressants

"Central Nervous System Depressants" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A very loosely defined group of drugs that tend to reduce the activity of the central nervous system. The major groups included here are ethyl alcohol, anesthetics, hypnotics and sedatives, narcotics, and tranquilizing agents (antipsychotics and antianxiety agents).

Descriptor ID	D002492
MeSH Number(s)	D27.505.696.277 D27.505.954.427.210
Concept/Terms	Central Nervous System Depressants Central Nervous System Depressants CNS Depressants Depressants, CNS

Below are MeSH descriptors whose meaning is more general than "Central Nervous System Depressants".

Chemicals and Drugs [D]
Chemical Actions and Uses [D27]
Pharmacologic Actions [D27.505]
Physiological Effects of Drugs [D27.505.696]
Central Nervous System Depressants [D27.505.696.277]
Therapeutic Uses [D27.505.954]
Central Nervous System Agents [D27.505.954.427]
Central Nervous System Depressants [D27.505.954.427.210]

Below are MeSH descriptors whose meaning is related to "Central Nervous System Depressants".

Below are MeSH descriptors whose meaning is more specific than "Central Nervous System Depressants".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Central Nervous System Depressants" by people in this website by year, and whether "Central Nervous System Depressants" was a major or minor topic of these publications.

Bar chart showing 19 publications over 12 distinct years, with a maximum of 3 publications in 2010

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	1	0	1
1999	1	0	1
2001	1	1	2
2003	1	0	1
2004	1	0	1
2006	1	0	1
2008	1	0	1
2010	1	2	3
2011	1	1	2
2013	0	2	2
2015	1	1	2
2017	2	0	2

Below are the most recent publications written about "Central Nervous System Depressants" by people in Profiles.

Ezquer F, Quintanilla ME, Morales P, Ezquer M, Lespay-Rebolledo C, Herrera-Marschitz M, Israel Y. Activated mesenchymal stem cell administration inhibits chronic alcohol drinking and suppresses relapse-like drinking in high-alcohol drinker rats. Addict Biol. 2019 01; 24(1):17-27.

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Aimino MA, Coker CR, Silberman Y. Acute ethanol modulation of neurocircuit function in the nucleus of the tractus solitarius. Brain Res Bull. 2018 04; 138:5-11.

View in: PubMed
Hartman RL, Brown TL, Milavetz G, Spurgin A, Gorelick DA, Gaffney G, Huestis MA. Controlled vaporized cannabis, with and without alcohol: subjective effects and oral fluid-blood cannabinoid relationships. Drug Test Anal. 2016 Jul; 8(7):690-701.

View in: PubMed
Kwako LE, Spagnolo PA, Schwandt ML, Thorsell A, George DT, Momenan R, Rio DE, Huestis M, Anizan S, Concheiro M, Sinha R, Heilig M. The corticotropin releasing hormone-1 (CRH1) receptor antagonist pexacerfont in alcohol dependence: a randomized controlled experimental medicine study. Neuropsychopharmacology. 2015 Mar 13; 40(5):1053-63.

View in: PubMed
Bennett DS, Mohamed FB, Carmody DP, Malik M, Faro SH, Lewis M. Prenatal tobacco exposure predicts differential brain function during working memory in early adolescence: a preliminary investigation. Brain Imaging Behav. 2013 Mar; 7(1):49-59.

View in: PubMed
DuBose CS, Chesler EJ, Goldowitz D, Hamre KM. Use of the expanded panel of BXD mice narrow QTL regions in ethanol-induced locomotor activation and motor incoordination. Alcohol Clin Exp Res. 2013 Jan; 37(1):170-83.

View in: PubMed
Addolorato G, Leggio L, Ferrulli A, Cardone S, Bedogni G, Caputo F, Gasbarrini G, Landolfi R. Dose-response effect of baclofen in reducing daily alcohol intake in alcohol dependence: secondary analysis of a randomized, double-blind, placebo-controlled trial. Alcohol Alcohol. 2011 May-Jun; 46(3):312-7.

View in: PubMed
Karahanian E, Quintanilla ME, Tampier L, Rivera-Meza M, Bustamante D, Gonzalez-Lira V, Morales P, Herrera-Marschitz M, Israel Y. Ethanol as a prodrug: brain metabolism of ethanol mediates its reinforcing effects. Alcohol Clin Exp Res. 2011 Apr; 35(4):606-12.

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Jedema HP, Carter MD, Dugan BP, Gurnsey K, Olsen AS, Bradberry CW. The acute impact of ethanol on cognitive performance in rhesus macaques. Cereb Cortex. 2011 Aug; 21(8):1783-91.

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Keegan J, Parva M, Finnegan M, Gerson A, Belden M. Addiction in pregnancy. J Addict Dis. 2010 Apr; 29(2):175-91.

View in: PubMed

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