"Chromosome Fragility" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Susceptibility of chromosomes to breakage leading to translocation; CHROMOSOME INVERSION; SEQUENCE DELETION; or other CHROMOSOME BREAKAGE related aberrations.
| Descriptor ID |
D002873
|
| MeSH Number(s) |
C23.550.210.110.180 C23.550.362.180.180 G05.365.590.175.165.180 G05.370.180.180
|
| Concept/Terms |
Chromosome Fragility- Chromosome Fragility
- Fragility, Chromosome
- Chromosomal Fragility
- Fragility, Chromosomal
|
Below are MeSH descriptors whose meaning is more general than "Chromosome Fragility".
Below are MeSH descriptors whose meaning is more specific than "Chromosome Fragility".
This graph shows the total number of publications written about "Chromosome Fragility" by people in this website by year, and whether "Chromosome Fragility" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 0 | 1 | 1 |
| 1998 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chromosome Fragility" by people in Profiles.
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Vahidnezhad H, Youssefian L, Saeidian AH, Uitto J. Phenotypic Spectrum of Epidermolysis Bullosa: The Paradigm of Syndromic versus Non-Syndromic Skin Fragility Disorders. J Invest Dermatol. 2019 03; 139(3):522-527.
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Iliopoulos D, Guler G, Han SY, Johnston D, Druck T, McCorkell KA, Palazzo J, McCue PA, Baffa R, Huebner K. Fragile genes as biomarkers: epigenetic control of WWOX and FHIT in lung, breast and bladder cancer. Oncogene. 2005 Feb 24; 24(9):1625-33.
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Huebner K, Druck T, Siprashvili Z, Croce CM, Kovatich A, McCue PA. The role of deletions at the FRA3B/FHIT locus in carcinogenesis. Recent Results Cancer Res. 1998; 154:200-15.
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Siprashvili Z, Sozzi G, Barnes LD, McCue P, Robinson AK, Eryomin V, Sard L, Tagliabue E, Greco A, Fusetti L, Schwartz G, Pierotti MA, Croce CM, Huebner K. Replacement of Fhit in cancer cells suppresses tumorigenicity. Proc Natl Acad Sci U S A. 1997 Dec 09; 94(25):13771-6.
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Ohta M, Inoue H, Cotticelli MG, Kastury K, Baffa R, Palazzo J, Siprashvili Z, Mori M, McCue P, Druck T, Croce CM, Huebner K. The FHIT gene, spanning the chromosome 3p14.2 fragile site and renal carcinoma-associated t(3;8) breakpoint, is abnormal in digestive tract cancers. Cell. 1996 Feb 23; 84(4):587-97.
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Balaban-Malenbaum G, Gilbert F, Nichols WW, Hill R, Shields J, Meadows AT. A deleted chromosome no. 13 in human retinoblastoma cells: relevance to tumorigenesis. Cancer Genet Cytogenet. 1981 Apr; 3(3):243-50.