"Crigler-Najjar Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A familial form of congenital hyperbilirubinemia transmitted as an autosomal recessive trait. It is characterized by icterus and brain damage caused by a glucuronyl transferase deficiency in the liver and faulty bilirubin conjugation.
| Descriptor ID |
D003414
|
| MeSH Number(s) |
C16.320.565.300.281 C18.452.648.300.281
|
| Concept/Terms |
Crigler-Najjar Syndrome- Crigler-Najjar Syndrome
- Crigler Najjar Syndrome, Type 1
- Crigler-Najar Syndrome
- Crigler Najar Syndrome
- Familial Nonhemolytic Unconjugated Hyperbilirubinemia
- Hereditary Unconjugated Hyperbilirubinemia
- Crigler Najjar Syndrome
- Crigler-Najjar Syndrome, Type I
- Crigler Najjar Syndrome, Type I
|
Below are MeSH descriptors whose meaning is more general than "Crigler-Najjar Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Crigler-Najjar Syndrome".
This graph shows the total number of publications written about "Crigler-Najjar Syndrome" by people in this website by year, and whether "Crigler-Najjar Syndrome" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2020 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Crigler-Najjar Syndrome" by people in Profiles.
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Aronson SJ, Junge N, Trabelsi M, Kelmemi W, Hubert A, Brigatti KW, Fox MD, de Knegt RJ, Escher JC, Ginocchio VM, Iorio R, Zhu Y, ?z?ay F, Rahim F, El-Shabrawi MHF, Shteyer E, Di Giorgio A, D'Antiga L, Mingozzi F, Brunetti-Pierri N, Strauss KA, Labrune P, Mrad R, Baumann U, Beuers U, Bosma PJ. Disease burden and management of Crigler-Najjar syndrome: Report of a world registry. Liver Int. 2022 07; 42(7):1593-1604.
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Strauss KA, Ahlfors CE, Soltys K, Mazareigos GV, Young M, Bowser LE, Fox MD, Squires JE, McKiernan P, Brigatti KW, Puffenberger EG, Carson VJ, Vreman HJ. Crigler-Najjar Syndrome Type 1: Pathophysiology, Natural History, and Therapeutic Frontier. Hepatology. 2020 06; 71(6):1923-1939.