Crohn Disease

"Crohn Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.

Descriptor ID	D003424
MeSH Number(s)	C06.405.205.731.500 C06.405.469.432.500
Concept/Terms	Crohn Disease Crohn Disease Crohn's Enteritis Regional Enteritis Crohn's Disease Crohns Disease Inflammatory Bowel Disease 1 Enteritis, Granulomatous Enteritis, Granulomatous Granulomatous Enteritis Enteritis, Regional Ileocolitis Ileocolitis Colitis, Granulomatous Colitis, Granulomatous Granulomatous Colitis Ileitis, Terminal Ileitis, Terminal Terminal Ileitis Ileitis, Regional Regional Ileitides Regional Ileitis

Below are MeSH descriptors whose meaning is more general than "Crohn Disease".

Diseases [C]
Digestive System Diseases [C06]
Gastrointestinal Diseases [C06.405]
Gastroenteritis [C06.405.205]
Inflammatory Bowel Diseases [C06.405.205.731]
Crohn Disease [C06.405.205.731.500]
Intestinal Diseases [C06.405.469]
Inflammatory Bowel Diseases [C06.405.469.432]
Crohn Disease [C06.405.469.432.500]

Below are MeSH descriptors whose meaning is related to "Crohn Disease".

Below are MeSH descriptors whose meaning is more specific than "Crohn Disease".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Crohn Disease" by people in this website by year, and whether "Crohn Disease" was a major or minor topic of these publications.

Bar chart showing 84 publications over 27 distinct years, with a maximum of 7 publications in 2013

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	2	0	2
1999	1	0	1
2000	1	0	1
2001	1	0	1
2003	0	2	2
2004	1	0	1
2005	2	1	3
2006	2	2	4
2008	1	1	2
2009	1	0	1
2010	2	2	4
2011	1	1	2
2012	5	0	5
2013	4	3	7
2014	1	0	1
2015	6	0	6
2016	5	0	5
2017	3	0	3
2018	2	1	3
2019	1	1	2
2020	4	0	4
2021	4	1	5
2022	6	0	6
2023	4	1	5
2024	4	1	5
2025	1	0	1

Below are the most recent publications written about "Crohn Disease" by people in Profiles.

Moses J, Adler J, Saeed SA, Firestine AM, Galanko JA, Ammoury RF, Bass DM, Bass JA, Bastidas M, Benkov KJ, Bousvaros A, Cabrera JM, Chun KY, Dorsey JM, Ebach DR, Gulati AS, Herfarth HH, Ivanova A, Jester TW, Kaplan JL, Kusek ME, Leibowitz IH, Linville TM, Margolis PA, Minar P, Molle-Rios Z, Niklinska-Schirtz BJ, Olano KK, Osaba L, Palomo PJ, Pashankar DS, Pitch L, Samson CM, Sandberg KC, Steiner SJ, Strople JA, Sullivan JS, Tung J, Wali P, Wohl DA, Zikry M, Boyle BM, Kappelman MD. Low Anti-Tumor Necrosis Factor Levels During Maintenance Phase Are Associated With Treatment Failure in Children With Crohn's Disease. Inflamm Bowel Dis. 2025 Jul 07; 31(7):1841-1850.

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Alsoudi AF, Wai KM, Koo E, McConnell RA, Pham NH, Do BK, Ludwig CA, Kossler AL, Mruthyunjaya P, Rahimy E. Risk of Intestinal Complications, Extraintestinal Morbidity, and Mortality in Patients with Crohn's Disease and Ocular Involvement. Ocul Immunol Inflamm. 2024 Dec; 32(10):2486-2493.

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Ghodasara SK, Hauser KM, Oldewurtel KM, Rolandelli RH, Nemeth ZH. A Comparison of Clinical Outcomes of Colectomies for Pediatric and Adult Patients With Inflammatory Bowel Disease. Am Surg. 2024 Nov; 90(11):2921-2929.

View in: PubMed
Sehgal P, Su S, Zech J, Nobel Y, Luk L, Economou I, Shen B, Lewis JD, Freedberg DE. Visceral Adiposity Independently Predicts Time to Flare in Inflammatory Bowel Disease but Body Mass Index Does Not. Inflamm Bowel Dis. 2024 04 03; 30(4):594-601.

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Godoy-Brewer G, Salem G, Limketkai B, Selaru FM, Grossen A, Policarpo T, Haq Z, Parian AM. Use of Biologics for the Treatment of Inflammatory Conditions of the Pouch: A Systematic Review. J Clin Gastroenterol. 2024 02 01; 58(2):183-194.

View in: PubMed
Ghodasara SK, Roskam JS, Uretsky M, Chang GC, Rolandelli RH, Nemeth ZH. Effects of the COVID-19 Pandemic on Colectomy Outcomes for Inflammatory Bowel Disease. South Med J. 2024 02; 117(2):88-92.

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Haliyur R, Kim JS, Mohan S, Iskowitz S, Bommakanti N, Bapuraj JR, Adler J, Elner VM, Demirci H. Orbital biopsy findings consistent with granulomatosis polyangiitis in a 14-year-old boy with Crohn's disease. Orbit. 2024 Dec; 43(6):762-765.

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Sherban A, Keller M. Recurrence of Metastatic Crohn's Disease after Surgical Resection. Skinmed. 2023; 21(5):366-369.

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Kappelman MD, Wohl DA, Herfarth HH, Firestine AM, Adler J, Ammoury RF, Aronow JE, Bass DM, Bass JA, Benkov K, Tobi CB, Boccieri ME, Boyle BM, Brinkman WB, Cabera JM, Chun K, Colletti RB, Dodds CM, Dorsey JM, Ebach DR, Entrena E, Forrest CB, Galanko JA, Grunow JE, Gulati AS, Ivanova A, Jester TW, Kaplan JL, Kugathasan S, Kusek ME, Leibowitz IH, Linville TM, Lipstein EA, Margolis PA, Minar P, Molle-Rios Z, Moses J, Olano KK, Osaba L, Palomo PJ, Pappa H, Park KT, Pashankar DS, Pitch L, Robinson M, Samson CM, Sandberg KC, Schuchard JR, Seid M, Shelly KA, Steiner SJ, Strople JA, Sullivan JS, Tung J, Wali P, Zikry M, Weinberger M, Saeed SA, Bousvaros A. Comparative Effectiveness of Anti-TNF in Combination With Low-Dose Methotrexate vs Anti-TNF Monotherapy in Pediatric Crohn's Disease: A Pragmatic Randomized Trial. Gastroenterology. 2023 07; 165(1):149-161.e7.

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Manski SA, Schlachterman A. Bypass of a Duodenal Stricture in Crohn's Disease Using a Lumen Opposing Metal Stent (LAMS): A Case Report. Inflamm Bowel Dis. 2023 01 05; 29(1):177-178.

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