"Cyclosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection.
| Descriptor ID |
D003524
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| MeSH Number(s) |
D04.345.566.235 D12.644.641.235
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Cyclosporins".
Below are MeSH descriptors whose meaning is more specific than "Cyclosporins".
This graph shows the total number of publications written about "Cyclosporins" by people in this website by year, and whether "Cyclosporins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cyclosporins" by people in Profiles.
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Manara MC, Perdichizzi S, Serra M, Pierini R, Benini S, Hattinger CM, Astolfi A, Bagnati R, D'Incalci M, Picci P, Scotlandi K. The molecular mechanisms responsible for resistance to ET-743 (Trabectidin; Yondelis) in the Ewing's sarcoma cell line, TC-71. Int J Oncol. 2005 Dec; 27(6):1605-16.
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Ben-Maimon CS, Burke JF, Besarab A, Jarrell BE, Francos GC, Moyer SS. Evidence against chronic progressive cyclosporine nephrotoxicity. Transplant Proc. 1991 Feb; 23(1 Pt 2):1260-2.
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Teixido M, Kron TK, Plainse M. Head and neck sequelae of cardiac transplantation. Laryngoscope. 1990 Mar; 100(3):231-6.
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Michael HJ, Francos GC, Burke JF, Besarab A, Moritz M, Gillum D, Jarrell B. A comparison of the effects of cyclosporine versus antilymphocyte globulin on delayed graft function in cadaver renal transplant recipients. Transplantation. 1989 Nov; 48(5):805-8.
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Kaiser BA, Lawless ST, Palmer JM, Dunn SP, Polinsky MS, Baluarte HJ. Safe conversion from cyclosporine to azathioprine with improved renal function in pediatric renal transplantation. Pediatr Nephrol. 1989 Oct; 3(4):401-5.
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Conti JA, Kramer N, Rosenstein ED. Cytophagic panniculitis and lupus panniculitis versus Weber-Christian disease. Am J Med. 1989 Jul; 87(1):3-4.
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McGregor RS, Zitelli BJ, Urbach AH, Malatack JJ, Gartner JC. Varicella in pediatric orthotopic liver transplant recipients. Pediatrics. 1989 Feb; 83(2):256-61.
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Bielory L, Holland C, Gascon P, Frohman L. Uveitis, cutaneous and neurosarcoid: treatment with low-dose cyclosporine A. Transplant Proc. 1988 Jun; 20(3 Suppl 4):144-8.
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Besarab A, Jarrell BE, Burke JF, Francos G, Caro J, Mallon E. "Erythrocytosis" in renal transplantation patients treated with cyclosporine. Transplant Proc. 1988 Jun; 20(3 Suppl 3):945-7.
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Harris DT, Kozumbo WJ, Cerutti PA, Cerottini JC. Mechanism of cyclosporin A-induced immunosuppression. Cyclosporin A inhibits receptor-mediated and non-receptor-mediated lymphokine production as well as interleukin-2-induced proliferation in cloned T lymphocytes. Cell Immunol. 1987 Oct 01; 109(1):104-14.