"Cysteamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mercaptoethylamine compound that is endogenously derived from the COENZYME A degradative pathway. The fact that cysteamine is readily transported into LYSOSOMES where it reacts with CYSTINE to form cysteine-cysteamine disulfide and CYSTEINE has led to its use in CYSTINE DEPLETING AGENTS for the treatment of CYSTINOSIS.
| Descriptor ID |
D003543
|
| MeSH Number(s) |
D02.092.471.562.369 D02.886.489.472.369
|
| Concept/Terms |
Cysteamine- Cysteamine
- beta-Mercaptoethylamine
- beta Mercaptoethylamine
- Mercaptoethylamine
- Mercamine
- Mercaptamine
- 2-Aminoethanethiol
- 2 Aminoethanethiol
- Cysteinamine
Cysteamine Bitartrate- Cysteamine Bitartrate
- Bitartrate, Cysteamine
- Cysteamine Tartrate (1:1)
- Cysteamine Tartrate
- Tartrate, Cysteamine
|
Below are MeSH descriptors whose meaning is more general than "Cysteamine".
Below are MeSH descriptors whose meaning is more specific than "Cysteamine".
This graph shows the total number of publications written about "Cysteamine" by people in this website by year, and whether "Cysteamine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cysteamine" by people in Profiles.
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Rossi S, Herrine SK, Navarro VJ. Cystinosis as a cause of noncirrhotic portal hypertension. Dig Dis Sci. 2005 Jul; 50(7):1372-5.
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Berruyer C, Martin FM, Castellano R, Macone A, Malergue F, Garrido-Urbani S, Millet V, Imbert J, Dupr? S, Pitari G, Naquet P, Galland F. Vanin-1-/- mice exhibit a glutathione-mediated tissue resistance to oxidative stress. Mol Cell Biol. 2004 Aug; 24(16):7214-24.
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Pitari G, Malergue F, Martin F, Philippe JM, Massucci MT, Chabret C, Maras B, Dupr? S, Naquet P, Galland F. Pantetheinase activity of membrane-bound Vanin-1: lack of free cysteamine in tissues of Vanin-1 deficient mice. FEBS Lett. 2000 Oct 20; 483(2-3):149-54.
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Assadi FK, McCue P, Jefferis S, Shi M, Beckman DA. Effects of pre- and postnatal cysteamine exposure on renal function in the rat. Pediatr Nephrol. 1999 Nov; 13(9):812-5.
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Gahl WA, Charnas L, Markello TC, Bernardini I, Ishak KG, Dalakas MC. Parenchymal organ cystine depletion with long-term cysteamine therapy. Biochem Med Metab Biol. 1992 Dec; 48(3):275-85.
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Pitari G, Maurizi G, Flati V, Ursini CL, Spera L, Dupr? S, Cavallini D. Enzymatic synthesis of S-aminoethyl-L-cysteine from pantetheine. Biochim Biophys Acta. 1992 Mar 05; 1116(1):27-33.
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Gahl WA, Bernardini I, Dalakas M, Rizzo WB, Harper GS, Hoeg JM, Hurko O, Bernar J. Oral carnitine therapy in children with cystinosis and renal Fanconi syndrome. J Clin Invest. 1988 Feb; 81(2):549-60.
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Szabo S, Haith LR, Reynolds ES. Pathogenesis of duodenal ulceration produced by cysteamine or propionitrile: influence of vagotomy, sympathectomy, histamine depletion, H-2 receptor antagonists and hormones. Dig Dis Sci. 1979 Jun; 24(6):471-7.
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Szabo S, Reynolds ES, Lictenberger LM, Haith LR, Dzau VJ. Pathogenesis of duodenal ulcer. Gastric hyperacidity caused by propionitrile and cysteamine in rats. Res Commun Chem Pathol Pharmacol. 1977 Feb; 16(2):311-23.