"Deoxycholic Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
| Descriptor ID |
D003840
|
| MeSH Number(s) |
D04.210.500.105.225.272 D04.210.500.221.430.342
|
| Concept/Terms |
Deoxycholic Acid- Deoxycholic Acid
- Acid, Deoxycholic
- Desoxycholic Acid
- Acid, Desoxycholic
- Dihydroxycholanoic Acid
- Acid, Dihydroxycholanoic
|
Below are MeSH descriptors whose meaning is more general than "Deoxycholic Acid".
Below are MeSH descriptors whose meaning is more specific than "Deoxycholic Acid".
This graph shows the total number of publications written about "Deoxycholic Acid" by people in this website by year, and whether "Deoxycholic Acid" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Deoxycholic Acid" by people in Profiles.
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Eilers SE, Torbeck R, Krishnasamy S, Khorasani H. Safe and Successful Administration of Deoxycholic Acid in a Patient With Chronic Active Liver Disease. Dermatol Surg. 2020 09; 46(9):1240-1242.
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Katragkou A, McCarthy M, Meletiadis J, Petraitis V, Moradi PW, Strauss GE, Fouant MM, Kovanda LL, Petraitiene R, Roilides E, Walsh TJ. In vitro combination of isavuconazole with micafungin or amphotericin B deoxycholate against medically important molds. Antimicrob Agents Chemother. 2014 Nov; 58(11):6934-7.
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Gong L, Debruyne PR, Witek M, Nielsen K, Snook A, Lin JE, Bombonati A, Palazzo J, Schulz S, Waldman SA. Bile acids initiate lineage-addicted gastroesophageal tumorigenesis by suppressing the EGF receptor-AKT axis. Clin Transl Sci. 2009 Aug; 2(4):286-93.
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Debruyne PR, Witek M, Gong L, Birbe R, Chervoneva I, Jin T, Domon-Cell C, Palazzo JP, Freund JN, Li P, Pitari GM, Schulz S, Waldman SA. Bile acids induce ectopic expression of intestinal guanylyl cyclase C Through nuclear factor-kappaB and Cdx2 in human esophageal cells. Gastroenterology. 2006 Apr; 130(4):1191-206.
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Herbert DR, Nolan TJ, Schad GA, Lustigman S, Abraham D. Immunoaffinity-isolated antigens induce protective immunity against larval Strongyloides stercoralis in mice. Exp Parasitol. 2002 Feb; 100(2):112-20.
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Bhamra R, Sa'ad A, Bolcsak LE, Janoff AS, Swenson CE. Behavior of amphotericin B lipid complex in plasma in vitro and in the circulation of rats. Antimicrob Agents Chemother. 1997 May; 41(5):886-92.
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Flynn PM, Shenep JL, Stokes DC, Fairclough D, Hildner WK. Polymyxin B moderates acidosis and hypotension in established, experimental gram-negative septicemia. J Infect Dis. 1987 Nov; 156(5):706-12.