An experimental animal model for central nervous system demyelinating disease. Inoculation with a white matter emulsion combined with FREUND'S ADJUVANT, myelin basic protein, or purified central myelin triggers a T cell-mediated immune response directed towards central myelin. The pathologic features are similar to MULTIPLE SCLEROSIS, including perivascular and periventricular foci of inflammation and demyelination. Subpial demyelination underlying meningeal infiltrations also occurs, which is also a feature of ENCEPHALOMYELITIS, ACUTE DISSEMINATED. Passive immunization with T-cells from an afflicted animal to a normal animal also induces this condition. (From Immunol Res 1998;17(1-2):217-27; Raine CS, Textbook of Neuropathology, 2nd ed, p604-5)

Descriptor ID	D004681
MeSH Number(s)	C10.114.703.300 C10.228.140.695.562.250 C10.314.350.250 C20.111.258.625.300 E05.598.500.500.500
Concept/Terms	Encephalomyelitis, Autoimmune, Experimental Encephalomyelitis, Autoimmune, Experimental Allergic Encephalomyelitis, Experimental Encephalomyelitis, Experimental Allergic Experimental Allergic Encephalomyelitides Autoimmune Encephalomyelitis, Experimental Experimental Autoimmune Encephalomyelitis Encephalomyelitis, Allergic Encephalomyelitis, Experimental Autoimmune Experimental Allergic Encephalomyelitis Allergic Encephalomyelitis Autoimmune Experimental Encephalomyelitis Encephalomyelitis, Autoimmune Experimental Experimental Encephalomyelitis, Autoimmune

Below are MeSH descriptors whose meaning is more general than "Encephalomyelitis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is related to "Encephalomyelitis, Autoimmune, Experimental".

Below are MeSH descriptors whose meaning is more specific than "Encephalomyelitis, Autoimmune, Experimental".