Disease Models, Animal

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"Disease Models, Animal" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Descriptor ID	D004195
MeSH Number(s)	C22.232 E05.598.500 E05.599.395.080
Concept/Terms	Disease Models, Animal Disease Models, Animal Animal Disease Model Animal Disease Models Disease Model, Animal

Below are MeSH descriptors whose meaning is more general than "Disease Models, Animal".

Diseases [C]
Animal Diseases [C22]
Disease Models, Animal [C22.232]
Analytical, Diagnostic and Therapeutic Techniques and Equipment [E]
Investigative Techniques [E05]
Models, Animal [E05.598]
Disease Models, Animal [E05.598.500]
Models, Theoretical [E05.599]
Models, Biological [E05.599.395]
Disease Models, Animal [E05.599.395.080]

Below are MeSH descriptors whose meaning is related to "Disease Models, Animal".

Below are MeSH descriptors whose meaning is more specific than "Disease Models, Animal".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Disease Models, Animal" by people in this website by year, and whether "Disease Models, Animal" was a major or minor topic of these publications.

Bar chart showing 1361 publications over 31 distinct years, with a maximum of 93 publications in 2011

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	12	13
1996	1	8	9
1997	3	24	27
1998	0	16	16
1999	2	9	11
2000	6	19	25
2001	0	22	22
2002	5	52	57
2003	4	28	32
2004	9	38	47
2005	10	51	61
2006	6	57	63
2007	17	62	79
2008	8	74	82
2009	10	75	85
2010	12	66	78
2011	9	84	93
2012	8	48	56
2013	8	50	58
2014	6	57	63
2015	1	44	45
2016	5	50	55
2017	1	54	55
2018	3	34	37
2019	3	33	36
2020	7	33	40
2021	1	51	52
2022	0	16	16
2023	1	10	11
2024	10	22	32
2025	2	3	5

Below are the most recent publications written about "Disease Models, Animal" by people in Profiles.

Khalife MR, Villarin C, Ruiz JM, McClelland SA, Rabbo KA, Matthew Mahoney J, Scott RC, Hernan AE. Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins after Early Life Seizures. eNeuro. 2025 Mar; 12(3).

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Wang J, Poskitt LE, Gallagher J, Puffenberger EG, Wynn RM, Shishodia G, Chuang DT, Beever J, Hardin DL, Brigatti KW, Baker WC, Gately R, Bertrand S, Rodrigues A, Benatti HR, Taghian T, Hall E, Prestigiacomo R, Liang J, Chen G, Zhou X, Ren L, Liu N, He R, Su Q, Xie J, Jiang Z, Gruntman A, Gray-Edwards H, Gao G, Strauss KA, Wang D. BCKDHA-BCKDHB digenic gene therapy restores metabolic homeostasis in two mouse models and a calf with classic maple syrup urine disease. Sci Transl Med. 2025 Feb 26; 17(787):eads0539.

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Navratilova E, Kopruszinski CM, Oyarzo J, Barber KR, Anderson T, Dodick DW, Schwedt TJ, Porreca F. Sex differences in effectiveness of CGRP receptor antagonism for treatment of acute and persistent headache-like pain in a mouse model of mild traumatic brain injury. Cephalalgia. 2025 Feb; 45(2):3331024251321087.

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Rosenblum JS, Cole Y, Dang D, Lookian PP, Alkaissi H, Patel M, Cappadona AJ, Jha A, Edwards N, Donahue DR, Munasinghe J, Wang H, Knutsen RH, Pappo AS, Lechan RM, Kozel BA, Smirniotopoulos JG, Kim HJ, Vortmeyer A, Miettinen M, Heiss JD, Zhuang Z, Pacak K. Head and neck paraganglioma in Pacak-Zhuang syndrome. JNCI Cancer Spectr. 2025 Jan 03; 9(1).

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Hao H, Yin T, Li T, Zhou X, Ren H, Liu M, Huang H, Qi C, Xiu Y, Qiu W, Wang D, Shi M, Wang X, Dumont AS, Liu Q. Inhibition of Bruton's tyrosine kinase restricts neuroinflammation following intracerebral hemorrhage. Theranostics. 2025; 15(2):494-508.

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Jiang C, Li Y, Duan K, Zhan T, Chen Z, Wang Y, Zhao R, Ma C, Guo Y, Liu C. [Parkin deletion affects PINK1/Parkin-mediated mitochondrial autophagy to exacerbate neuroinflammation and accelerate progression of Parkinson's disease in mice]. Nan Fang Yi Ke Da Xue Xue Bao. 2024 Dec 20; 44(12):2359-2366.

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Khan M, Farooqi S, Mitchell KL, Chowdhury SKR, Cabrera-Ayala M, Huang J, Wallace DC, Weiss SL. Effect of sodium butyrate on kidney and liver mitochondrial dysfunction in a lipopolysaccharide mouse?model. FASEB J. 2024 Dec 15; 38(23):e70228.

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McCord JL, Han JYS, Staudt RE, Philp NJ, Snyder CM. Immune responses drive chorioretinitis and retinal pathology after neonatal CMV infection. Sci Adv. 2024 Nov 22; 10(47):eadn6379.

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Gomez-Galvez Y, Gupta M, Kaur M, Fusco S, Podda MV, Grassi C, Srivastava AK, Iacovitti L, Blanco-Suarez E. Recovery after human bone marrow mesenchymal stem cells (hBM-MSCs)-derived extracellular vesicles (EVs) treatment in post-MCAO rats requires repeated handling. PLoS One. 2024; 19(10):e0312298.

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Lemanski EA, Collins BA, Ebenezer AT, Anilkumar S, Langdon VA, Zheng Q, Ding S, Franke KR, Schwarz JM, Wright-Jin EC. A Novel Non-Invasive Murine Model of Neonatal Hypoxic-Ischemic Encephalopathy Demonstrates Developmental Delay and Motor Deficits with Activation of Inflammatory Pathways in Monocytes. Cells. 2024 Sep 14; 13(18).

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