"Enoyl-CoA Hydratase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme that catalyzes reversibly the hydration of unsaturated fatty acyl-CoA to yield beta-hydroxyacyl-CoA. It plays a role in the oxidation of fatty acids and in mitochondrial fatty acid synthesis, has broad specificity, and is most active with crotonyl-CoA. EC 4.2.1.17.
| Descriptor ID |
D004746
|
| MeSH Number(s) |
D08.811.520.241.300.250
|
| Concept/Terms |
Enoyl-CoA Hydratase- Enoyl-CoA Hydratase
- Enoyl CoA Hydratase
- Hydratase, Enoyl-CoA
- 3-Hydroxyacyl Dehydratases
- 3 Hydroxyacyl Dehydratases
- Dehydratases, 3-Hydroxyacyl
- beta-Hydroxyacyl Dehydratases
- Dehydratases, beta-Hydroxyacyl
- beta Hydroxyacyl Dehydratases
- beta-Hydroxyacyl-CoA Dehydrases
- Dehydrases, beta-Hydroxyacyl-CoA
- beta Hydroxyacyl CoA Dehydrases
- trans-2-Enoyl-Coenzyme A Hydratase
- Hydratase, trans-2-Enoyl-Coenzyme A
- trans 2 Enoyl Coenzyme A Hydratase
- Enoyl CoA Hydratases
- CoA Hydratases, Enoyl
- Hydratases, Enoyl CoA
- Enoyl Hydrase
- Hydrase, Enoyl
- 3-Hydroxyacyl CoA Hydrolyases
- 3 Hydroxyacyl CoA Hydrolyases
- CoA Hydrolyases, 3-Hydroxyacyl
- Hydrolyases, 3-Hydroxyacyl CoA
- Crotonase
|
Below are MeSH descriptors whose meaning is more general than "Enoyl-CoA Hydratase".
Below are MeSH descriptors whose meaning is more specific than "Enoyl-CoA Hydratase".
This graph shows the total number of publications written about "Enoyl-CoA Hydratase" by people in this website by year, and whether "Enoyl-CoA Hydratase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 1 | 0 | 1 |
| 2002 | 2 | 0 | 2 |
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Below are the most recent publications written about "Enoyl-CoA Hydratase" by people in Profiles.
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D'Ordine RL, Pawlak J, Bahnson BJ, Anderson VE. Polarization of cinnamoyl-CoA substrates bound to enoyl-CoA hydratase: correlation of (13)C NMR with quantum mechanical calculations and calculation of electronic strain energy. Biochemistry. 2002 Feb 26; 41(8):2630-40.
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Bahnson BJ, Anderson VE, Petsko GA. Structural mechanism of enoyl-CoA hydratase: three atoms from a single water are added in either an E1cb stepwise or concerted fashion. Biochemistry. 2002 Feb 26; 41(8):2621-9.
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D'Ordine RL, Bahnson BJ, Tonge PJ, Anderson VE. Enoyl-coenzyme A hydratase-catalyzed exchange of the alpha-protons of coenzyme A thiol esters: a model for an enolized intermediate in the enzyme-catalyzed elimination? Biochemistry. 1994 Dec 13; 33(49):14733-42.
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Bahnson BJ, Anderson VE. Crotonase-catalyzed beta-elimination is concerted: a double isotope effect study. Biochemistry. 1991 Jun 18; 30(24):5894-906.
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Bahnson BJ, Anderson VE. Isotope effects on the crotonase reaction. Biochemistry. 1989 May 16; 28(10):4173-81.